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Thermodynamics constrains the flow of matter in a reaction network to occur through routes along which the Gibbs energy decreases, implying that viable steady-state flux patterns should be void of closed reaction cycles. Identifying and…

分子网络 · 定量生物学 2013-10-15 Daniele De Martino , Fabrizio Capuani , Matteo Mori , Andrea De Martino , Enzo Marinari

Chaotic dynamics have emerged as a versatile resource for neuromorphic and probabilistic computing, enabling high-dimensional nonlinear processing and classical analogues of quantum randomness. Exploiting chaos for computation requires…

混沌动力学 · 物理学 2026-05-20 Jungyoon Kim , Kyuho Kim , Kunwoo Park , Namkyoo Park , Sunkyu Yu

Life is characterized by a myriad of complex dynamic processes allowing organisms to grow, reproduce, and evolve. Physical approaches for describing systems out of thermodynamic equilibrium have been increasingly applied to living systems,…

生物物理 · 物理学 2020-12-16 Xiaona Fang , Karsten Kruse , Ting Lu , Jin Wang

The simulated self-assembly of molecular building blocks into functional complexes is a key area of study in computational biology and materials science. Self-assembly simulations of proteins using physically-motivated potentials for…

软凝聚态物质 · 物理学 2025-09-03 Ivan Spirandelli , Arnur Nigmetov , Dmitriy Morozov , Myfanwy E. Evans

We measure different contributions to entropy production in a living functional epithelial tissue. We do this by extracting the functional dynamics of development while at the same time quantifying fluctuations. Using the translucent…

软凝聚态物质 · 物理学 2023-01-25 Mark Olenik , Jake Turley , Stephen Cross , Helen Weavers , Paul Martin , Isaac Chenchiah , Tanniemola Liverpool

Kinetic proofreading mechanisms explain the extraordinary accuracy observed in central biological events in terms of the enhanced specificity of substrate selection networks under a nonequilibrium environment. The nonequilibrium steady…

适应与自组织系统 · 物理学 2022-06-29 Premashis Kumar , Kinshuk Banerjee , Gautam Gangopadhyay

The unique capability of quantum mechanics to evolve alternative possibilities in parallel is appealing and over the years a number of quantum algorithms have been developed offering great computational benefits. Systems coupled to the…

无序系统与神经网络 · 物理学 2013-11-20 Gabor Vattay , Stuart A. Kauffman

While there has been a keen interest in studying computation at the edge of chaos for dynamical systems undergoing a phase transition, this has come under question for cellular automata. We show that for continuously deformed cellular…

元胞自动机与格子气 · 物理学 2019-04-15 E. Estevez-Rams , D. Estevez-Moya , K. Garcia-Medina , R. Lora-Serrano

Biological cells can actively tune their intracellular architecture according to their overall shape. Here we explore the rheological implication of such coupling in a minimal model of a dense cellular material where each cell exerts an…

软凝聚态物质 · 物理学 2022-04-13 Shao-Zhen Lin , Matthias Merkel , Jean-François Rupprecht

Quantum computers are predicted to utilize quantum states to perform memory and to process tasks far faster than those of conventional classical computers. In this paper we show a new road towards building fault tolerance quantum computer…

量子物理 · 物理学 2008-06-10 Su-Peng Kou

We introduce a new framework for constructing topological quantum memories, by recasting error recovery as a dynamical process on a field generating cellular automaton. We envisage quantum systems controlled by a classical hardware composed…

量子物理 · 物理学 2015-10-28 Michael Herold , Earl T. Campbell , Jens Eisert , Michael J. Kastoryano

We study the dynamical process of equilibration of topological properties in quantum many-body systems undergoing a parameter quench between two topologically inequivalent Hamiltonians. This scenario is motivated by recent experiments on…

量子气体 · 物理学 2018-11-26 Andreas Kruckenhauser , Jan Carl Budich

We propose an innovative design for quantum batteries (QBs) that involves coupling two-level systems to a topological photonic waveguide. Employing the resolvent method, we analytically explore the thermodynamic performance of QBs. First,…

量子物理 · 物理学 2025-05-26 Zhi-Guang Lu , Guoqing Tian , Xin-You Lü , Cheng Shang

All living cells transport molecules and ions across membranes, often against concentration gradients. This active transport requires continual energy expenditure and is clearly a nonequilibrium process for which standard equilibrium…

亚细胞过程 · 定量生物学 2007-05-23 Robert W. Finkel

Biological membranes and vesicles play a central role in living systems, forming dynamic interfaces that regulate cellular organization and function. Classical descriptions of membrane mechanics that are rooted in equilibrium statistical…

软凝聚态物质 · 物理学 2026-02-24 Sreekanth Ramesh , Prashant K. Purohit , Yashashree Kulkarni

Spontaneous structural rearrangements play a central role in the organization and function of complex biomolecular systems. In principle, physics-based computer simulations like Molecular Dynamics (MD) enable us to investigate these…

量子物理 · 物理学 2026-03-19 Danial Ghamari , Philipp Hauke , Roberto Covino , Pietro Faccioli

Networks of biochemical reactions, like cellular metabolic networks, are kept in non-equilibrium steady states by the exchange fluxes connecting them to the environment. In most cases, feasible flux configurations can be derived from…

分子网络 · 定量生物学 2014-12-01 Daniele De Martino , Fabrizio Capuani , Andrea De Martino

The promise of chemical computation lies in controlling systems incompatible with traditional electronic micro-controllers, with applications in synthetic biology and nano-scale manufacturing. Computation is typically embedded in…

新兴技术 · 计算机科学 2019-02-11 Keenan Breik , Chris Thachuk , Marijn Heule , David Soloveichik

The modelling and analysis of biological systems has deep roots in Mathematics, specifically in the field of ordinary differential equations (ODEs). Alternative approaches based on formal calculi, often derived from process algebras or term…

Generating new molecules is fundamental to advancing critical applications such as drug discovery and material synthesis. Flows can generate molecules effectively by inverting the encoding process, however, existing flow models either…

机器学习 · 计算机科学 2022-10-14 Yogesh Verma , Samuel Kaski , Markus Heinonen , Vikas Garg