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I show the assumed Bilayer structure of cell membranes is Topologically falsified by known aminophospholipid dynamics in metabolically-active, Far from Equilibrium cells. The sensitivity of lipid and cytoplasmic flows to temperature,…

生物物理 · 物理学 2011-11-09 J. T. Lofthouse

We present the design for a thermodynamic computer that can perform arbitrary nonlinear calculations in or out of equilibrium. Simple thermodynamic circuits, fluctuating degrees of freedom in contact with a thermal bath and confined by a…

统计力学 · 物理学 2026-01-08 Stephen Whitelam , Corneel Casert

Topological and geometrical properties and the associated topological defects find a rapidly growing interest in studying the interplay between mechanics and the collective behavior of cells on the tissue level. We here test if well studied…

软凝聚态物质 · 物理学 2023-09-06 Dennis Wenzel , Simon Praetorius , Axel Voigt

Living systems are capable of locomotion, reconfiguration, and replication. To perform these tasks, cells spatiotemporally coordinate the interactions of force-generating, "active" molecules that create and manipulate non-equilibrium…

软凝聚态物质 · 物理学 2019-08-28 Tyler D. Ross , Heun Jin Lee , Zijie Qu , Rachel A. Banks , Rob Phillips , Matt Thomson

Living cells use readout molecules to record the state of receptor proteins, similar to measurements or copies in typical computational devices. But is this analogy rigorous? Can cells be optimally efficient, and if not, why? We show that,…

分子网络 · 定量生物学 2017-04-12 Thomas E. Ouldridge , Christopher C. Govern , Pieter Rein ten Wolde

This paper studies fault-tolerant quantum computation with gapped boundaries. We first introduce gapped boundaries of Kitaev's quantum double models for Dijkgraaf-Witten theories using their Hamiltonian realizations. We classify the…

量子物理 · 物理学 2016-10-18 Iris Cong , Meng Cheng , Zhenghan Wang

Uncovering the rules governing the nonequilibrium dynamics of the membranes that define biological cells is of central importance to understanding the physics of living systems. We theoretically and computationally investigate the behavior…

System and synthetic biology are rapidly evolving systems, but both lack tools such as those used in engineering environments to shift the their focus from the design of parts (details) to the design of systems (behaviors); to aggravate,…

新兴技术 · 计算机科学 2015-07-29 Ricardo Henrique Gracini Guiraldelli , Vincenzo Manca

A scalable quantum computer could be built by networking together many simple processor cells, thus avoiding the need to create a single complex structure. The difficulty is that realistic quantum links are very error prone. A solution is…

量子物理 · 物理学 2013-04-26 Naomi H. Nickerson , Ying Li , Simon C. Benjamin

Collective cell migration governs a range of physiological and pathological processes, from tissue morphogenesis to cancer invasion, in which topological defects arise as an inevitable consequence of frequent cellular rearrangement and…

软凝聚态物质 · 物理学 2026-04-01 Jiusi Zhang , Chung Wing Chan , Bo Li , Rui Zhang

Thermo-osmotic flows, generated by applying a thermal gradient along a liquid-solid interface, could be harnessed to convert waste heat into electricity. While this phenomenon has been known for almost a century, there is a crucial need to…

软凝聚态物质 · 物理学 2024-07-15 Mehdi Ouadfel , Samy Merabia , Yasutaka Yamaguchi , Laurent Joly

Unlike macroscopic engines, the molecular machinery of living cells is strongly affected by fluctuations. Stochastic Thermodynamics uses Markovian jump processes to model the random transitions between the chemical and configurational…

统计力学 · 物理学 2015-10-19 Bernhard Altaner , Artur Wachtel , Jürgen Vollmer

Engineering synthetic materials that mimic the remarkable complexity of living organisms is a fundamental challenge in science and technology. We study the spatiotemporal patterns that emerge when an active nematicfilm of microtubules and…

Cells control fluid flows with a spatial and temporal precision that far exceeds the capabilities of current microfluidic technologies. Cells achieve this superior spatio-temporal control by harnessing dynamic networks of cytoskeleton and…

软凝聚态物质 · 物理学 2025-05-26 Fan Yang , Shichen Liu , Heun Jin Lee , Rob Phillips , Matt Thomson

This is a comprehensive review on fault-tolerant topological quantum computation with the surface codes. The basic concepts and useful tools underlying fault-tolerant quantum computation, such as universal quantum computation, stabilizer…

量子物理 · 物理学 2015-04-08 Keisuke Fujii

The energetically most efficient way how a deformed red blood cell regains equilibrium is mathematically described by the gradient flow of the Canham-Helfrich functional, including a spontaneous curvature and the conservation of surface…

偏微分方程分析 · 数学 2024-08-15 Fabian Rupp , Christian Scharrer , Manuel Schlierf

Many-body topological quantum states host exotic quantum phenomena and lie at the forefront of developing next-generation quantum technologies. Recently emerged neural network wavefunction methods have established themselves as a powerful…

强关联电子 · 物理学 2026-04-13 Haoxiang Chen , Yubing Qian , Weiluo Ren , Xiang Li , Ji Chen

The mechanical behaviour and symmetry-breaking shape deformation of red blood cells subjected to shear flows is used to demonstrate that far from being random fluids, both the membrane and cytoplasm of every biological cell undergo…

综合物理 · 物理学 2007-05-23 Juanita Lofthouse

Lipid bilayer membranes are the fundamental biological barriers that permit life. The bilayer dynamics largely participates in orchestrating cellular workings and is characterized by substantial stability together with extreme plasticity…

软凝聚态物质 · 物理学 2022-12-05 Matteo Bottacchiari , Mirko Gallo , Marco Bussoletti , Carlo Massimo Casciola

Molecular transport maintains cellular structures and functions. For example, lipid and protein diffusion sculpts the dynamic shapes and structures on the cell membrane that perform essential cellular functions, such as cell signaling.…

软凝聚态物质 · 物理学 2024-04-17 Saurav G. Varma , Argha Mitra , Sumantra Sarkar
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