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Plasma proteins such as fibrinogen induce the aggregation of red blood cells (RBC) into rouleaux, which are responsible for the pronounced shear thinning behavior of blood, control the erythro- cyte sedimentation rate (ESR) a common…

Red blood cells (RBCs) sustain mechanical stresses associated with microcirculatory flow through ATP-driven plasma membrane flickering. This is an active phenomenon driven by motor proteins that regulate interactions between the spectrin…

Osmotic conditions play an important role in the cell properties of human red blood cells (RBCs), which are crucial for the pathological analysis of some blood diseases such as malaria. Over the past decades, numerous efforts have mainly…

Red blood cells possess unique biomechanical ability to squeeze through capillaries smaller than their size to enable gas and ion exchange. A key signature of their active biomechanics is the out-of-equilibrium fluctuation of the plasma…

Many types of bacteria swim by rotating a bundle of helical filaments also called flagella. Each filament is driven by a rotary motor and a very flexible hook transmits the motor torque to the filament. We model it by discretizing…

生物物理 · 物理学 2012-01-04 Reinhard Vogel , Holger Stark

It is known from the wave-like motion of microtubules in motility assays that the piconewton forces that motors produce can be sufficient to bend the filaments. In cellular phenomena such as cytosplasmic streaming, molecular motors…

软凝聚态物质 · 物理学 2017-07-11 Gabriele De Canio , Eric Lauga , Raymond E. Goldstein

The twisting and writhing of a cell body and associated mechanical stresses is an underappreciated constraint on microbial self-propulsion. Multi-flagellated bacteria can even buckle and writhe under their own activity as they swim through…

软凝聚态物质 · 物理学 2023-09-25 Wilson Lough , Douglas B. Weibel , Saverio E. Spagnolie

In this paper, we analyze the inverse dynamics and control of a bacteria-inspired uniflagellar robot in a fluid medium at low Reynolds number. Inspired by the mechanism behind the locomotion of flagellated bacteria, we consider a robot…

机器人学 · 计算机科学 2020-12-22 Mojtaba Forghani , Weicheng Huang , M. Khalid Jawed

The dynamics of red blood cells (RBCs) in simple shear flow was studied using a theoretical approach based on three variables: a shape parameter, the inclination angle $\theta$, and phase angle $\phi$ of the membrane rotation. At high shear…

软凝聚态物质 · 物理学 2009-08-07 Hiroshi Noguchi

Light-actuated motors, vehicles, and even space sails have drawn tremendous attention for basic science and applications in space, biomedical, and sensing domains. Optical bound states in the continuum (BIC) are topological singularities of…

光学 · 物理学 2022-04-06 Haoye Qin , Walid Redjem , Boubacar Kante

The ability of cells to undergo reversible shape changes is often crucial to their survival. For Red Blood Cells (RBCs), irreversible alteration of the cell shape and flexibility often causes anemia. Here we show theoretically that RBCs may…

细胞行为 · 定量生物学 2015-06-03 Maria Zeitz , Pierre Sens

We present a numerical analysis of the lateral movement and equilibrium radial positions of red blood cells (RBCs) with major diameter of 8 $\mu$m under a Newtonian fluid in a circular channel with 50-$\mu$m diameter. Each RBC, modelled as…

Red Blood Cells (RBCs) are the simplest cell types with complex dynamical and viscoelastic phenomenology. While the mechanical rigidity and the flickering noise of RBCs have been extensively investigated, an accurate determination of the…

生物物理 · 物理学 2023-08-25 M. Gironella-Torrent , G. Bergamaschi , R. Sorkin , G. Wuite , F. Ritort

E. coli bacteria swim following a run and tumble pattern. In the run state all flagella join in a single helical bundle that propels the cell body along approximately straight paths. When one or more flagellar motors reverse direction the…

软凝聚态物质 · 物理学 2015-07-01 S. Bianchi , F. Saglimbeni , A. Lepore , R. Di Leonardo

We investigate the dynamics of the Red Blood Cell (RBC) in microfluidic channels under oscillatory flows. The simulations employ a hybrid continuum-particle approach, in which the cell membrane and cytosol fluid are modeled using…

流体动力学 · 物理学 2023-07-18 Lahcen Akerkouch , Trung Bao Le

In growing plant cells, parallel ordering of microtubules (MTs) along the inner surface of the cell membrane influences the direction of cell expansion and thereby plant morphology. For correct expansion of organs that primarily grow by…

生物物理 · 物理学 2019-09-05 Sven Bachmann , Richard Froese , Eric N Cytrynbaum

We consider the motion of red blood cells and other non-spherical microcapsules dilutely suspended in a simple shear flow. Our analysis indicates that depending on the viscosity, membrane elasticity, geometry and shear rate, the particle…

软凝聚态物质 · 物理学 2015-06-25 J. M. Skotheim , T. W. Secomb

The influence of the internal structure of a biological cell (e.g., a leukocyte) on its dynamics and rheology is not yet fully understood. By using 2D numerical simulations of a bilamellar vesicle (BLV) consisting of two vesicles as a cell…

软凝聚态物质 · 物理学 2014-07-08 Badr Kaoui , Timm Krüger , Jens Harting

Ultra-cold RbCs molecules in high-lying vibrational levels of the a$^3\Sigma^+$ ground electronic state are confined in an optical trap. Inelastic collision rates of these molecules with both Rb and Cs atoms are determined for individual…

Driven or active suspensions can display fascinating collective behavior, where coherent motions or structures arise on a scale much larger than that of the constituent particles. Here, we report experiments and numerical simulations…

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