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Spatio-temporal reasoning is a remarkable capability of Vision Language Models (VLMs), but the underlying mechanisms of such abilities remain largely opaque. We postulate that visual/geometrical and textual representations of spatial…

计算机视觉与模式识别 · 计算机科学 2026-01-21 Raphi Kang , Hongqiao Chen , Georgia Gkioxari , Pietro Perona

Most cortical inhibitory cell types exclusively express one of three genes, parvalbumin, somatostatin and 5HT3a. The visual responses of cortical neurons are affected not only by local cues, but also by visual context. As the inhibitory…

神经元与认知 · 定量生物学 2018-06-18 Jung H. Lee , Christof Koch , Stefan Mihalas

We consider a model of basic inner retinal connectivity where bipolar and amacrine cells interconnect, and both cell types project onto ganglion cells, modulating their response output to the brain visual areas. We derive an analytical…

神经元与认知 · 定量生物学 2024-01-10 Evgenia Kartsaki , Gerrit Hilgen , Evelyne Sernagor , Bruno Cessac

Cortical neurons exhibit a hierarchy of timescales across brain regions in response to input stimuli, which is thought to be crucial for information processing of different temporal scales. Modeling studies suggest that both intra-regional…

神经元与认知 · 定量生物学 2024-12-24 Yang Qi , Jiexiang Wang , Weiyang Ding , Gustavo Deco , Viktor Jirsa , Wenlian Lu , Jianfeng Feng

Vagus nerve stimulation (VNS) has emerged as a promising therapeutic intervention across various neurological and psychiatric conditions, including epilepsy, depression, and stroke rehabilitation; however, its mechanisms of action on neural…

神经元与认知 · 定量生物学 2025-02-03 Shinichi Kumagai , Tomoyo Isoguchi Shiramatsu , Kensuke Kawai , Hirokazu Takahashi

The brain exhibits capabilities of fast incremental learning from few noisy examples, as well as the ability to associate similar memories in autonomously-created categories and to combine contextual hints with sensory perceptions. Together…

In this paper we first recall the definition of geometical model of the visual cortex, focusing in particular on the geometrical properties of horizontal cortical connectivity. Then we recognize that histograms of edges - co-occurrences are…

计算机视觉与模式识别 · 计算机科学 2019-06-11 Giovanna Citti , Alessandro Sarti

Learning and interpreting the structure of the environment is an innate feature of biological systems, and is integral to guiding flexible behaviours for evolutionary viability. The concept of a cognitive map has emerged as one of the…

神经元与认知 · 定量生物学 2022-02-04 James C. R. Whittington , David McCaffary , Jacob J. W. Bakermans , Timothy E. J. Behrens

Convolutional neural networks (CNNs) have been shown to be state-of-the-art models for visual cortical neurons. Cortical neurons in the primary visual cortex are sensitive to contextual information mediated by extensive horizontal and…

计算机视觉与模式识别 · 计算机科学 2025-03-03 Isaac Lin , Tianye Wang , Shang Gao , Shiming Tang , Tai Sing Lee

Memory for the past makes use of a record of what happened when---a function over past time. Time cells in the hippocampus and temporal context cells in the entorhinal cortex both code for events as a function of past time, but with very…

神经元与认知 · 定量生物学 2020-03-27 Marc W. Howard , Michael E. Hasselmo

We typically think of cells as responding to external signals independently by regulating their gene expression levels, yet they often locally exchange information and coordinate. Can such spatial coupling be of benefit for conveying…

分子网络 · 定量生物学 2015-01-19 Thomas R. Sokolowski , Gašper Tkačik

Cells contain elaborate and interconnected networks of protein polymers which make up the cytoskeleton. The cytoskeleton governs the internal positioning and movement of vesicles and organelles, and controls dynamic changes in cell…

生物物理 · 物理学 2017-01-24 Lishibanya Mohapatra , Bruce L. Goode , Predrag Jelenkovic , Rob Phillips , Jane Kondev

Brain state regulates sensory processing and motor control for adaptive behavior. Internal mechanisms of brain state control are well studied, but the role of external modulation from the environment is not well understood. Here, we…

In the mammalian brain, newly acquired memories depend on the hippocampus for maintenance and recall, but over time the neocortex takes over these functions, rendering memories hippocampus-independent. The process responsible for this…

神经元与认知 · 定量生物学 2021-07-02 Peter Helfer , Thomas R. Shultz

Hippocampal formation (HF) can rapidly adapt to varied environments and build flexible working memory (WM). To mirror the HF's mechanism on generalization and WM, we propose a model named Generalization and Associative Temporary Encoding…

神经元与认知 · 定量生物学 2025-01-23 Yuechen Liu , Zishun Wang , Chen Qiao , Zongben Xu

Correlated fluctuations in the activity of neural populations reflect the network's dynamics and connectivity. The temporal and spatial dimensions of neural correlations are interdependent. However, prior theoretical work mainly analyzed…

神经元与认知 · 定量生物学 2022-07-19 Yan-Liang Shi , Roxana Zeraati , Anna Levina , Tatiana A. Engel

Many neurons in the visual cortex are orientation-selective, increase their firing rate with contrast and are modulated by attention. What is the cortical circuit that underlies these computations? We examine how synchrony can be modulated…

神经元与认知 · 定量生物学 2007-05-23 Paul H. E. Tiesinga , Calin I. Buia

The visual system is hierarchically organized to process visual information in successive stages. Neural representations vary drastically across the first stages of visual processing: at the output of the retina, ganglion cell receptive…

神经元与认知 · 定量生物学 2019-01-07 Jack Lindsey , Samuel A. Ocko , Surya Ganguli , Stephane Deny

Brain stimulation is a powerful tool for understanding cortical function and holds promise for therapeutic interventions in neuropsychiatric disorders. Initial visual prosthetics apply electric microstimulation to early visual cortex which…

神经元与认知 · 定量生物学 2025-10-07 Johannes Mehrer , Ben Lonnqvist , Anna Mitola , Abdulkadir Gokce , Paolo Papale , Martin Schrimpf

We investigate theoretically the effect of spatial attention on the contrast-response function (CRF) and orientation-tuning curves in early visual areas.We look at a model of a hypercolumn developed recently (Persi et al., 2008), that…

神经元与认知 · 定量生物学 2008-06-26 Erez Persi