相关论文: A possible role of chemotaxis in germinal center f…
During germinal center reactions the appearance of two specific zones is observed: the dark and the light zone. Up to now, the origin and function of these zones are poorly understood. In the framework of a stochastic and discrete model…
The specific morphology of germinal centers is analyzed in the context of the optimization of the humoral immune response. The relevance of dark and light zones for the affinity maturation process is investigated in the framework of a…
This presentation examines the centre vortex structure of Monte-Carlo generated gauge-field configurations using modern visualisation techniques. This time, the manner in which light dynamical fermion degrees of freedom impact the…
We introduce a new model for the dynamics of centroblasts and centrocytes in a germinal center. The model reduces the germinal center reaction to the elements considered as essential and embeds proliferation of centroblasts, point mutations…
We study the effect of chemotactic signaling among mesenchymal cells. We show that the particular physiology of the mesenchymal cells allows one-dimensional collapse in contrast to the case of bacteria, and that the mesenchymal…
We study the formation of Dark Matter nuclei in scenarios where DM particles are baryons of a new confining gauge force. The dark nucleosynthesis is analogous to the formation of light elements in the SM and requires as a first step the…
We demonstrate that active rotations in chemically signalling particles, such as autochemotactic {\it E. coli} close to walls, create a route for pattern formation based on a nonlinear yet deterministic instability mechanism. For slow…
Successful biological development via spatial regulation of cell differentiation relies on action of multiple signaling molecules that are known as morphogens. It is now well established that signaling molecules create non-uniform…
We show that composite fermions with masses much smaller than the scale of confinement arise naturally in certain models which admit dynamical breakdown of chiral symmetry. The models are such that to leading order some of the fermions…
Chemotactic bacteria have been observed to congregate into highly regular patterns. When the bacteria are placed in the center of a dish, a wave of bacteria can travel outward, leaving a regular pattern of spots or stripes in its wake.…
The non-trivial ground-state vacuum fields of QCD form the foundation of matter. Here we examine the centre vortices identified within the ground-state fields of lattice QCD. We aim to understand the manner in which dynamical fermions in…
We discuss how the centres of galaxy clusters evolve in time, showing the results of a series of direct N-body simulations. In particular, we followed the evolution of a galaxy cluster with a mass $M_{clus} \simeq 10^{14} $M$_{\odot}$ in…
Based on flat Friedmann-Robertson Walker cold dark matter (CDM) type models driven by non-relativistic matter and an exotic fluid (quintessence) with an equation of state: $p_{Q}=w\rho_{Q}$ ($-1\le w<0$), we investigate whether or not the…
Three-dimensional cultures of cells are gaining popularity as an in vitro improvement over 2D Petri dishes. In many such experiments, cells have been found to organize in aggregates. We present new results of three-dimensional in vitro…
It has been proposed that during the early steps in the origin of life, small droplets could have formed via the segregation of molecules from complex mixtures by phase separation. These droplets could have provided chemical reaction…
Lymphocyte selection is a fundamental operation of adaptive immunity. In order to produce B-lymphocytes with a desired antigenic profile, a process of mutation-selection occurs in the germinal center, which is part of the lymph nodes. We…
Chemotaxis receptors in E. coli form clusters at the cell poles and also laterally along the cell body, and this clustering plays an important role in signal transduction. Recently, experiments using flourrescence imaging have shown that,…
Complex spatial patterns in biological systems often arise through self-organization without a central coordination, guided by local interactions and chemical signaling. In this study, we explore how motility-dependent chemical deposition…
A brief overview of recent advances in the study of star formation in the Galactic Center (GC) environment is presented. Particular attention is paid to new insights concerning the suppression of star formation in GC molecular clouds.…
Emergence of collective dynamical chirality (CDC) at mesoscopic scales plays a key role in many formation processes of chiral structures in nature, which may also provide possible routines for people to fabricate complex chiral…