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A key process in the life of any multicellular organism is its development from a single egg into a full grown adult. The first step in this process often consists of forming a tissue layer out of randomly placed cells on the surface of the…

We present results from the first robust investigation of galaxy morphology as a function of environment at z>1.5. Our study is motivated by the fact that star-forming galaxies contained within a protocluster at z=2.3 in the HS1700+64 field…

Polymers with active segments constitute prospective future materials and are used as a model for some biological systems such as chromatin. The directions of the active forces are typically introduced with temporal or spatial correlations…

软凝聚态物质 · 物理学 2024-11-25 Adam H. T. P. Höfler , Iurii Chubak , Christos N. Likos , Jan Smrek

Topological defects provide a unifying language to describe how orientational order breaks down in active and living matter. Considering cells as elongated particles confluent, epithelial tissues can be interpreted as nematic fields and its…

The formation of new bone involves both the deposition of bone matrix, and the formation of a network of cells embedded within the bone matrix, called osteocytes. Osteocytes derive from bone-synthesising cells (osteoblasts) that become…

细胞行为 · 定量生物学 2014-12-15 Pascal R Buenzli

How multicellular life forms evolved out from unicellular ones constitutes a major problem in our understanding of the evolution of our biosphere. A recent set of experiments involving yeast cell populations has shown that selection for…

种群与进化 · 定量生物学 2015-11-10 Salva Duran-Nebreda , Ricard V. Solé

The erythrocyte sedimentation rate is one of the oldest medical diagnostic methods whose physical mechanisms remain debatable up to date. Using both light microscopy and mesoscale cell-level simulations, we show that erythrocytes form a…

In multicellular organisms, relations among parts and between parts and the whole are contextual and interdependent. These organisms and their cells are ontogenetically linked: an organism starts as a cell that divides producing…

其他定量生物学 · 定量生物学 2017-09-15 Maël Montévil , Lucia Speroni , Carlos Sonnenschein , Ana M. Soto

The asymptotic shape of randomly growing radial clusters is studied. We pose the problem in terms of the dynamics of stochastic partial differential equations. We concentrate on the properties of the realizations of the stochastic growth…

统计力学 · 物理学 2012-01-17 Carlos Escudero

Deformations of cell sheets during morphogenesis are driven by developmental processes such as cell division and cell shape changes. In morphoelastic shell theories of development, these processes appear as variations of the intrinsic…

软凝聚态物质 · 物理学 2021-03-03 Pierre A. Haas , Raymond E. Goldstein

Prestellar cores are generally spheroidal, some of which appear oblate while others appear prolate. Very few of them appear circular in projection. Little, however, is understood about the processes or the physical conditions under which…

星系天体物理 · 物理学 2022-04-13 S. Anathpindika , J. Di Francesco

The formation of pyramid-like structures in thin-film growth on substrates with a quadratic symmetry, e.g., {001} surfaces, is shown to exhibit anisotropic scaling as there exist two length scales with different time dependences. Analytical…

统计力学 · 物理学 2009-10-31 Martin Siegert

Mitsumatsu constructed leafwise symplectic structures of certain codimension one foliations of the 5-sphere. This inspired the present author to improve his result on convergence of contact structure to foliation. We describe convergence of…

几何拓扑 · 数学 2017-07-17 Atsuhide Mori

Cell fate decisions in multicellular organisms are precisely coordinated, leading to highly reproducible macroscopic outcomes of developmental processes. The origins of this reproducibility can be found at the molecular level during the…

分子网络 · 定量生物学 2013-09-25 Mariela D. Petkova , Feng Liu , Thomas Gregor

Engineering synthetic materials that mimic the remarkable complexity of living organisms is a fundamental challenge in science and technology. We study the spatiotemporal patterns that emerge when an active nematicfilm of microtubules and…

Organogenesis is a tightly regulated process that has been studied experimentally for decades. We are developing mechanistic models for the morphogenesis of limbs, lungs, and kidneys with a view to integrate available knowledge and to…

组织与器官 · 定量生物学 2012-10-03 Denis Menshykau , Dagmar Iber

This paper provides experimental and numerical evidence supporting the occurrence of liposome congregation at the floors of meteor craters on Early Earth. This work builds on our earlier research, which demonstrated that liposomes submerged…

地球与行星天体物理 · 物理学 2026-02-25 Vladimir M. Subbotin , Benjamin A. Turner , Brian A. Davies , Alric G. Lopez , Gennady Fiksel

We study the probabilities of evolution based on random mutations and natural selection. We conclude that evolution to multicellular eukaryots, or even prokaryots, is unlikely to be the result of only random mutations. Complex organisms…

种群与进化 · 定量生物学 2007-05-23 B. Hoeneisen , G. Trueba

One of the key findings of the Rosetta's mission to the Jupiter family comet 67P/Churyumov-Gerasimenko was its peculiar bilobed shape along with the apparent north/south dichotomy in large scale morphology. This has re-ignited scientific…

地球与行星天体物理 · 物理学 2020-02-19 Yuhui Zhao , Ladislav Rezac , Yuri Skorov , Jian-Yang Li

Experiments of in vitro formation of blood vessels show that cells randomly spread on a gel matrix autonomously organize to form a connected vascular network. We propose a simple model which reproduces many features of the biological…

统计力学 · 物理学 2009-11-10 A. Gamba , D. Ambrosi , A. Coniglio , A. de Candia , S. Di Talia , E. Giraudo , G. Serini , L. Preziosi , F. Bussolino