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相关论文: On the Benjamini--Hochberg method

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We address a common problem in large-scale data analysis, and especially the field of genetics, the huge-scale testing problem, where millions to billions of hypotheses are tested together creating a computational challenge to perform…

统计方法学 · 统计学 2015-01-22 Vered Madar , Sandra Batista

The Bonferroni multiple testing procedure is commonly perceived as being overly conservative in large-scale simultaneous testing situations such as those that arise in microarray data analysis. The objective of the present study is to show…

应用统计 · 统计学 2009-09-29 Alexander Gordon , Galina Glazko , Xing Qiu , Andrei Yakovlev

We consider the problem of comparing a reference distribution with several other distributions. Given a sample from both the reference and the comparison groups, we aim to identify the comparison groups whose distributions differ from that…

统计方法学 · 统计学 2025-11-26 Yonghoon Lee , Edgar Dobriban , Eric Tchetgen Tchetgen

False discovery rate (FDR) is a commonly used criterion in multiple testing and the Benjamini-Hochberg (BH) procedure is arguably the most popular approach with FDR guarantee. To improve power, the adaptive BH procedure has been proposed by…

统计方法学 · 统计学 2023-10-11 Zijun Gao

Consider a set of order statistics that arise from sorting samples from two different populations, each with their own, possibly different distribution function. The probability that these order statistics fall in disjoint, ordered…

统计计算 · 统计学 2007-06-26 Deborah H. Glueck , Anis Karimpour-Fard , Jan Mandel , Keith E. Muller

Tests of equality of copulas between two samples are introduced and studied using the empirical Bernstein copula process. Three statistics are proposed and their asymptotic properties are established. Besides, a subsampling Bernstein…

统计理论 · 数学 2023-12-19 Guanjie Lyu , Mohamed Belalia

The knockoff-based multiple testing setup of Barber & Candes (2015) for variable selection in multiple regression where sample size is as large as the number of explanatory variables is considered. The method of Benjamini & Hochberg (1995)…

统计方法学 · 统计学 2021-08-20 Sanat K. Sarkar , Cheng Yong Tang

In this paper, we focus on testing multivariate normality using the BHEP test with data that are missing completely at random. Our objective is twofold: first, to gain insight into the asymptotic behavior of BHEP test statistics under two…

统计方法学 · 统计学 2024-04-11 Danijel Aleksić , Bojana Milošević

We consider large-scale studies in which thousands of significance tests are performed simultaneously. In some of these studies, the multiple testing procedure can be severely biased by latent confounding factors such as batch effects and…

统计方法学 · 统计学 2016-06-21 Jingshu Wang , Qingyuan Zhao , Trevor Hastie , Art B. Owen

Modern data analysis frequently involves large-scale hypothesis testing, which naturally gives rise to the problem of maintaining control of a suitable type I error rate, such as the false discovery rate (FDR). In many biomedical and…

统计方法学 · 统计学 2023-07-25 David S. Robertson , James M. S. Wason , Aaditya Ramdas

The Benjamini-Hochberg (BH) procedure remains widely popular despite having limited theoretical guarantees in the commonly encountered scenario of correlated test statistics. Of particular concern is the possibility that the method could…

统计理论 · 数学 2023-11-14 Dan M. Kluger , Art B. Owen

To find interesting items in genome-wide association studies or next generation sequencing data, a crucial point is to design powerful false discovery rate (FDR) controlling procedures that suitably combine discrete tests (typically…

统计理论 · 数学 2017-09-18 Sebastian Döhler , Guillermo Durand , Etienne Roquain

The present paper establishes new multiple procedures for simultaneous testing of a large number of hypotheses under dependence. Special attention is devoted to experiments with rare false hypotheses. This sparsity assumption is typically…

统计理论 · 数学 2019-10-01 Marc Ditzhaus , Arnold Janssen

Consider the problem of testing $s$ hypotheses simultaneously. The usual approach restricts attention to procedures that control the probability of even one false rejection, the familywise error rate (FWER). If $s$ is large, one might be…

统计理论 · 数学 2007-11-06 Joseph P. Romano , Michael Wolf

Recently, Sturma, Drton, and Leung proposed a general-purpose stochastic method for hypothesis testing in models defined by polynomial equality and inequality constraints. Notably, the method remains theoretically valid even near irregular…

种群与进化 · 定量生物学 2025-07-21 David Barnhill , Marina Garrote-López , Elizabeth Gross , Max Hill , Bryson Kagy , John A. Rhodes , Joy Z. Zhang

We introduce a new class of methods for finite-sample false discovery rate (FDR) control in multiple testing problems with dependent test statistics where the dependence is fully or partially known. Our approach separately calibrates a…

统计方法学 · 统计学 2020-07-22 William Fithian , Lihua Lei

In this article, we propose a one-sample test to check whether the support of the unknown distribution generating the data is homologically equivalent to the support of some specified distribution or not OR using the corresponding…

统计方法学 · 统计学 2023-12-01 Satish Kumar , Subhra Sankar Dhar

Consider the problem of simultaneously testing null hypotheses H_1,...,H_s. The usual approach to dealing with the multiplicity problem is to restrict attention to procedures that control the familywise error rate (FWER), the probability of…

统计理论 · 数学 2007-06-13 E. L. Lehmann , Joseph P. Romano

Considering the knockoff-based multiple testing framework of Barber and Cand\`es [2015], we revisit the method of Sarkar and Tang [2022] and identify it as a specific case of an un-normalized e-value weighted Benjamini-Hochberg procedure.…

统计方法学 · 统计学 2026-02-13 Aniket Biswas , Aaditya Ramdas

We study an online multiple testing problem where the hypotheses arrive sequentially in a stream. The test statistics are independent and assumed to have the same distribution under their respective null hypotheses. We investigate two…

统计理论 · 数学 2017-05-30 Shiyun Chen , Ery Arias-Castro