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相关论文: A Fixed-Length Coding Algorithm for DNA Sequence C…

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The process of DNA-based data storage (DNA storage for short) can be mathematically modelled as a communication channel, termed DNA storage channel, whose inputs and outputs are sets of unordered sequences. To design error correcting codes…

信息论 · 计算机科学 2020-06-11 Wentu Song , Kui Cai , Kees A. Schouhamer Immink

Motivation The Burrows-Wheeler transform (BWT) is the foundation of many algorithms for compression and indexing of text data, but the cost of computing the BWT of very large string collections has prevented these techniques from being…

数据结构与算法 · 计算机科学 2015-03-20 Anthony J. Cox , Markus J. Bauer , Tobias Jakobi , Giovanna Rosone

The efficient storage of digital data is becoming very challenging over the years due to the exponential increase in the generation of data which can't compete with the existing storage resources. Furthermore, the infrequently accessed data…

新兴技术 · 计算机科学 2021-03-18 Melpomeni Dimopoulou , Eva Gil San Antonio , Marc Antonini

Motivation: Data volumes generated by next-generation sequencing technolo- gies is now a major concern, both for storage and transmission. This triggered the need for more efficient methods than general purpose compression tools, such as…

数据结构与算法 · 计算机科学 2014-12-19 Gaëtan Benoit , Claire Lemaitre , Dominique Lavenier , Guillaume Rizk

Most DNA sequencing technologies are based on the shotgun paradigm: many short reads are obtained from random unknown locations in the DNA sequence. A fundamental question, studied in arXiv:1203.6233, is what read length and coverage depth…

信息论 · 计算机科学 2022-02-09 Aditya Narayan Ravi , Alireza Vahid , Ilan Shomorony

The biggest challenge when using DNA as a storage medium is maintaining its stability. The relative occurrence of Guanine (G) and Cytosine (C) is essential for the longevity of DNA. In addition to that, reverse complementary base pairs…

信息论 · 计算机科学 2023-08-03 NallappaBhavithran G , Selvakumar R

This paper describes a new method of data encoding which may be used in various modern digital, computer and telecommunication systems and devices. The method permits the compression of data for storage or transmission, allowing the exact…

信息论 · 计算机科学 2012-01-27 Igor Nesiolovskiy , Artem Nesiolovskiy

Being able to store and transmit human genome sequences is an important part in genomic research and industrial applications. The complete human genome has 3.1 billion base pairs (haploid), and storing the entire genome naively takes about…

基因组学 · 定量生物学 2020-10-07 Anirduddha Laud , Gaurav Menghani , Madhava Keralapura

Error-correcting codes over sets, with applications to DNA storage, are studied. The DNA-storage channel receives a set of sequences, and produces a corrupted version of the set, including sequence loss, symbol substitution, symbol…

信息论 · 计算机科学 2021-07-12 Hengjia Wei , Moshe Schwartz

Due to their sequential nature, traditional DNA synthesis methods are expensive in terms of time and resources. They also fabricate multiple copies of the same strand, introducing redundancy. This redundancy can be leveraged to enhance the…

信息论 · 计算机科学 2025-10-29 Frederik Walter , Yonatan Yehezkeally

This paper introduces a new solution to DNA storage that integrates all three steps of retrieval, namely clustering, reconstruction, and error correction. DNA-correcting codes are presented as a unique solution to the problem of ensuring…

信息论 · 计算机科学 2024-07-02 Avital Boruchovsky , Daniella Bar-Lev , Eitan Yaakobi

Over the past years, the ever-growing trend on data storage demand, more specifically for "cold" data (rarely accessed data), has motivated research for alternative systems of data storage. Because of its biochemical characteristics,…

图像与视频处理 · 电气工程与系统科学 2023-06-23 Xavier Pic , Eva Gil San Antonio , Melpomeni Dimopoulou , Marc Antonini

In a distributed information application an encoder compresses an arbitrary vector while a similar reference vector is available to the decoder as side information. For the Hamming-distance similarity measure, and when guaranteed perfect…

信息论 · 计算机科学 2020-09-08 Yuval Cassuto , Jacob Ziv

DNA storage systems face significant challenges, including insertion, deletion, and substitution (IDS) errors. Therefore, designing effective synchronization codes, i.e., codes capable of correcting IDS errors, is essential for DNA storage…

信息论 · 计算机科学 2025-05-23 Javad Haghighat , Tolga M. Duman

We consider the problem of efficiently designing sets (codes) of equal-length DNA strings (words) that satisfy certain combinatorial constraints. This problem has numerous motivations including DNA computing and DNA self-assembly. Previous…

数据结构与算法 · 计算机科学 2007-05-23 Ming-Yang Kao , Manan Sanghi , Robert Schweller

Most of the attention in statistical compression is given to the space used by the compressed sequence, a problem completely solved with optimal prefix codes. However, in many applications, the storage space used to represent the prefix…

数据结构与算法 · 计算机科学 2015-06-30 Travis Gagie , Gonzalo Navarro , Yakov Nekrich , Alberto Ordóñez

In this paper, we present a novel design strategy of DNA codes with length $3n$ over the non-chain ring $R=\mathbb{Z}_4+u\mathbb{Z}_4+u^2\mathbb{Z}_4$ with $64$ elements and $u^3=1$, where $n$ denotes the length of a code over $R$. We first…

信息论 · 计算机科学 2022-11-28 Shibsankar Das , Krishna Gopal Benerjee , Adrish Banerjee

We study permutations over the set of $\ell$-grams, that are feasible in the sense that there is a sequence whose $\ell$-gram frequency has the same ranking as the permutation. Codes, which are sets of feasible permutations, protect…

信息论 · 计算机科学 2021-01-18 Niv Beeri , Moshe Schwartz

Although the expenses associated with DNA sequencing have been rapidly decreasing, the current cost of sequencing information stands at roughly $120/GB, which is dramatically more expensive than reading from existing archival storage…

离散数学 · 计算机科学 2023-11-30 Daniella Bar-Lev , Omer Sabary , Ryan Gabrys , Eitan Yaakobi

DNA as a data storage medium has several advantages, including far greater data density compared to electronic media. We propose that schemes for data storage in the DNA of living organisms may benefit from studying the reconstruction…

信息论 · 计算机科学 2019-09-10 Yonatan Yehezkeally , Moshe Schwartz