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Machine Learning methods have of late made significant efforts to solving multidisciplinary problems in the field of cancer classification using microarray gene expression data. Feature subset selection methods can play an important role in…

计算工程、金融与科学 · 计算机科学 2013-03-04 G. Prat , Ll. Belanche

We propose new, optimal methods for analyzing randomized trials, when it is suspected that treatment effects may differ in two predefined subpopulations. Such sub-populations could be defined by a biomarker or risk factor measured at…

统计方法学 · 统计学 2016-11-26 Michael Rosenblum , Han Liu , and En-Hsu Yen

We are concerned with the problem of designing large families of subsets over a common labeled ground set that have small pairwise intersections and the property that the maximum discrepancy of the label values within each of the sets is…

信息论 · 计算机科学 2019-01-18 R. Gabrys , H. S. Dau , C. J. Colbourn , O. Milenkovic

We introduce Deep Adaptive Design (DAD), a method for amortizing the cost of adaptive Bayesian experimental design that allows experiments to be run in real-time. Traditional sequential Bayesian optimal experimental design approaches…

机器学习 · 统计学 2021-06-14 Adam Foster , Desi R. Ivanova , Ilyas Malik , Tom Rainforth

Diversification in a set of solutions has become a hot research topic in the evolutionary computation community. It has been proven beneficial for optimisation problems in several ways, such as computing a diverse set of high-quality…

神经与进化计算 · 计算机科学 2022-07-29 Adel Nikfarjam , Amirhossein Moosavi , Aneta Neumann , Frank Neumann

The paper provides global optimization algorithms for two particularly difficult nonconvex problems raised by hybrid system identification: switching linear regression and bounded-error estimation. While most works focus on local…

机器学习 · 计算机科学 2017-11-27 Fabien Lauer

The problem of column subset selection has recently attracted a large body of research, with feature selection serving as one obvious and important application. Among the techniques that have been applied to solve this problem, the greedy…

数据结构与算法 · 计算机科学 2021-11-16 Jason Altschuler , Aditya Bhaskara , Gang Fu , Vahab Mirrokni , Afshin Rostamizadeh , Morteza Zadimoghaddam

Combinatorial optimization algorithm is essential in computer-aided drug design by progressively exploring chemical space to design lead compounds with high affinity to target protein. However current methods face inherent challenges in…

生物大分子 · 定量生物学 2025-07-23 Hao Tuo , Yan Li , Xuanning Hu , Haishi Zhao , Xueyan Liu , Bo Yang

The problem of multi-objective design of sparse MIMO arrays for better multitarget detection capabilities is considered. A novel approach for efficient utilization of the antenna design resources; namely, the number of available array…

信号处理 · 电气工程与系统科学 2022-10-24 Suleyman Gokhun Tanyer , Paul Dent , Murtaza Ali , Curtis Davis , SenthinelKumar Rajagopal , Peter Driessen

In this paper, we propose a new framework for designing fast parallel algorithms for fundamental statistical subset selection tasks that include feature selection and experimental design. Such tasks are known to be weakly submodular and are…

机器学习 · 计算机科学 2021-04-02 Sharon Qian , Yaron Singer

Genetic Algorithms (GAs) are used to solve search and optimization problems in which an optimal solution can be found using an iterative process with probabilistic and non-deterministic transitions. However, depending on the problem's…

分布式、并行与集群计算 · 计算机科学 2019-01-23 Matheus F. Torquato , Marcelo A. C. Fernandes

Decision trees have been a very popular class of predictive models for decades due to their interpretability and good performance on categorical features. However, they are not always robust and tend to overfit the data. Additionally, if…

机器学习 · 计算机科学 2019-08-14 Oktay Gunluk , Jayant Kalagnanam , Minhan Li , Matt Menickelly , Katya Scheinberg

The rapid advances in the field of optimization methods in many pure and applied science pose the difficulty of keeping track of the developments as well as selecting an appropriate technique that best suits the problem in-hand. From a…

神经与进化计算 · 计算机科学 2011-12-30 Loris Serafino

Classification in the dissimilarity space has become a very active research area since it provides a possibility to learn from data given in the form of pairwise non-metric dissimilarities, which otherwise would be difficult to cope with.…

Gradient porous structured materials possess significant potential of being applied in many engineering fields. To accelerate the design process of infill graded microstructures, a novel asymptotic homogenisation topology optimisation…

计算工程、金融与科学 · 计算机科学 2019-12-18 Dingchuan Xue , Yichao Zhu , Shaoshuai Li , Chang Liu , Weisheng Zhang , Xu Guo

Quantum optimal control plays a crucial role in the development of quantum technologies, particularly in the design and implementation of fast and accurate gates for quantum computing. Here, we present a method to synthesize gates using the…

In this work, we deal with the problem of computing a comprehensive front of efficient solutions in multi-objective portfolio optimization problems in presence of sparsity constraints. We start the discussion pointing out some weaknesses of…

最优化与控制 · 数学 2025-09-23 Arturo Annunziata , Matteo Lapucci , Pieluigi Mansueto , Davide Pucci

Many modern multiclass and multilabel problems are characterized by increasingly large output spaces. For these problems, label embeddings have been shown to be a useful primitive that can improve computational and statistical efficiency.…

机器学习 · 计算机科学 2015-07-07 Paul Mineiro , Nikos Karampatziakis

We consider the projected gradient algorithm for the nonconvex best subset selection problem that minimizes a given empirical loss function under an $\ell_0$-norm constraint. Through decomposing the feasible set of the given sparsity…

最优化与控制 · 数学 2026-02-13 Jan Harold Alcantara , Ching-pei Lee

This contribution examines optimization problems that involve stochastic dominance constraints. These problems have uncountably many constraints. We develop methods to solve the optimization problem by reducing the constraints to a finite…

最优化与控制 · 数学 2025-02-27 Rajmadan Lakshmanan , Alois Pichler , Miloš Kopa