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Generative artificial intelligence models learn probability distributions from data and produce novel samples that capture the salient properties of their training sets. Proteins are particularly attractive for such approaches given their…

生物大分子 · 定量生物学 2026-02-27 Filippo Stocco , Michele Garibbo , Noelia Ferruz

Given a set of species whose evolution is represented by a species tree, a gene family is a group of genes having evolved from a single ancestral gene. A gene family evolves along the branches of a species tree through various mechanisms,…

组合数学 · 数学 2019-05-14 Cedric Chauve , Yann Ponty , Michael Wallner

Lots of bio-inspired research works have been conducted in self-adaptive software. They have focused on the external behavior of biological entities without their genetic material that causes this behavior and constitutes the challenge this…

软件工程 · 计算机科学 2019-04-30 Enas Nafar , Said Ghoul

Exploration of task mappings plays a crucial role in achieving high performance in heterogeneous multi-processor system-on-chip (MPSoC) platforms. The problem of optimally mapping a set of tasks onto a set of given heterogeneous processors…

性能 · 计算机科学 2014-07-01 Wei Quan , Andy D. Pimentel

Although optimization is the longstanding algorithmic backbone of machine learning, new models still require the time-consuming implementation of new solvers. As a result, there are thousands of implementations of optimization algorithms…

机器学习 · 计算机科学 2019-06-03 Sören Laue , Matthias Mitterreiter , Joachim Giesen

Predicting genetic perturbations enables the identification of potentially crucial genes prior to wet-lab experiments, significantly improving overall experimental efficiency. Since genes are the foundation of cellular life, building gene…

定量方法 · 定量生物学 2025-05-09 Changxi Chi , Jun Xia , Jingbo Zhou , Jiabei Cheng , Chang Yu , Stan Z. Li

In the near future, all the human genes will be identified. But understanding the functions coded in the genes is a much harder problem. For example, by using block entropy, one has that the DNA code is closer to a random code then written…

数值分析 · 数学 2007-07-13 Torbjörn Lundh

Motivation: ``Molecular signatures'' or ``gene-expression signatures'' are used to predict patients' characteristics using data from coexpressed genes. Signatures can enhance understanding about biological mechanisms and have diagnostic…

定量方法 · 定量生物学 2007-05-23 Ramon Diaz-Uriarte

This paper proposes Genetic Algorithm with Border Trades (GAB), a novel modification of the standard genetic algorithm that enhances exploration by incorporating new chromosome patterns in the breeding process. This approach significantly…

机器学习 · 计算机科学 2025-06-27 Qingchuan Lyu

This paper presents our computational methodology using Genetic Algorithms (GA) for exploring the nature of RNA editing. These models are constructed using several genetic editing characteristics that are gleaned from the RNA editing system…

神经与进化计算 · 计算机科学 2007-05-23 C. Huang , L. M. Rocha

Evolutionary algorithms are wildly used in unmanned aerial vehicle path planning for their flexibility and effectiveness. Nevertheless, they are so sensitive to the change of environment that can't adapt to all scenarios. Due to this…

神经与进化计算 · 计算机科学 2022-04-08 Jiabin Lou , Rong Ding , Wenjun Wu

There is growing consensus among neuroscientists that neural circuits critical for survival are the result of genomic decompression processes. We introduce SynaptoGen, a novel computational framework--member of the Connectome Models…

神经与进化计算 · 计算机科学 2025-09-09 Tommaso Boccato , Matteo Ferrante , Nicola Toschi

Neural network models of real-world systems, such as industrial processes, made from sensor data must often rely on incomplete data. System states may not all be known, sensor data may be biased or noisy, and it is not often known which…

神经与进化计算 · 计算机科学 2007-06-08 Donald A. Sofge , David L. Elliott

The renaissance of neural architecture search (NAS) has seen classical methods such as genetic algorithms (GA) and genetic programming (GP) being exploited for convolutional neural network (CNN) architectures. While recent work have…

计算机视觉与模式识别 · 计算机科学 2020-12-04 Clifford Broni-Bediako , Yuki Murata , Luiz Henrique Mormille , Masayasu Atsumi

Grammatical Evolution (GE) is one of the most popular Genetic Programming (GP) variants, and it has been used with success in several problem domains. Since the original proposal, many enhancements have been proposed to GE in order to…

神经与进化计算 · 计算机科学 2021-03-16 Jessica Mégane , Nuno Lourenço , Penousal Machado

Some genes can change their relative locations in a genome. Thus for different individuals of the same species, the orders of genes might be different. Such jumping genes are called transposons. A practical problem is to determine…

基因组学 · 定量生物学 2022-09-02 Yue Wang

Predictive coding is a message-passing framework initially developed to model information processing in the brain, and now also topic of research in machine learning due to some interesting properties. One of such properties is the natural…

机器学习 · 计算机科学 2022-12-12 Billy Byiringiro , Tommaso Salvatori , Thomas Lukasiewicz

The application of deep learning methods, particularly foundation models, in biological research has surged in recent years. These models can be text-based or trained on underlying biological data, especially omics data of various types.…

人工智能 · 计算机科学 2024-12-06 Yoav Kan-Tor , Michael Morris Danziger , Eden Zohar , Matan Ninio , Yishai Shimoni

This paper presents a new type of genetic algorithm for the set covering problem. It differs from previous evolutionary approaches first because it is an indirect algorithm, i.e. the actual solutions are found by an external decoder…

神经与进化计算 · 计算机科学 2010-07-05 Uwe Aickelin

GitHub Copilot, an extension for the Visual Studio Code development environment powered by the large-scale language model Codex, makes automatic program synthesis available for software developers. This model has been extensively studied in…

软件工程 · 计算机科学 2021-11-16 Dominik Sobania , Martin Briesch , Franz Rothlauf
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