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We have developed a coarse-grained formulation for modeling the dynamic behavior of cells quantitatively, based on stochasticity and heterogeneity, rather than on biochemical reactions. We treat each reaction as a continuous-time stochastic…

分子网络 · 定量生物学 2015-05-28 Shunsuke Teraguchi , Yutaro Kumagai , Alexis Vandenbon , Shizuo Akira , Daron M Standley

By means of molecular dynamics simulations we examine the aging process of a strong glass former, a silica melt modeled by the BKS potential. The system is quenched from a temperature above to one below the critical temperature, and the…

无序系统与神经网络 · 物理学 2007-05-23 H. Wahlen , H. Rieger

Unraveling the dynamical motions of biomolecules is essential for bridging their structure and function, yet it remains a major computational challenge. Molecular dynamics (MD) simulation provides a detailed depiction of biomolecular…

生物大分子 · 定量生物学 2025-09-17 Allan dos Santos Costa , Manvitha Ponnapati , Dana Rubin , Tess Smidt , Joseph Jacobson

We study the dynamical evolution of globular clusters using our 2D Monte Carlo code with the inclusion of primordial binary interactions for equal-mass stars. We use approximate analytical cross sections for energy generation from…

天体物理学 · 物理学 2009-11-07 J. M. Fregeau , M. A. Gurkan , K. J. Joshi , F. A. Rasio

The dynamical behavior of the column that made up binary granular beads is investigated systematically by tracking the displacement of particles in the collapse process. An experimental setup is first devised to control the quasi-static…

软凝聚态物质 · 物理学 2019-03-26 Hongwei Zhu , Yaodong Feng , Danfeng Lu , Yahya Sandali , Bin Li , Gang Sun , Ning Zheng , Qingfan Shi

We demonstrate the stencil growth of nanoscale patterns using molecular dynamic simulation. A comparison has been made to a film grown by identical conditions without a stencil. It is shown that in the case of nanoscale proximity between…

介观与纳米尺度物理 · 物理学 2020-12-07 Movaffaq Kateb

Quantum molecular dynamics is applied to study the ground state properties of nuclear matter at subsaturation densities. Clustering effects are observed as to soften the equation of state at these densities. The structure of nuclear matter…

Continuum models for the spatial dynamics of growing cell populations have been widely used to investigate the mechanisms underpinning tissue development and tumour invasion. These models consist of nonlinear partial differential equations…

组织与器官 · 定量生物学 2019-07-15 Mark AJ Chaplain , Tommaso Lorenzi , Fiona R Macfarlane

Droplets are essential for spatially controlling biomolecules in cells. To work properly, cells need to control the emergence and morphology of droplets. On the one hand, driven chemical reactions can affect droplets profoundly. For…

软凝聚态物质 · 物理学 2024-03-14 Noah Ziethen , David Zwicker

Pore forming toxins (PFTs) are virulent proteins released by several species, including many strains of bacteria, to attack and kill host cells. In this article, we focus on the utility of molecular dynamics (MD) simulations and the…

软凝聚态物质 · 物理学 2021-08-17 Rajat Desikan , Amit Behera , Prabal K. Maiti , K. Ganapathy Ayappa

The dynamics of glass formation in monatomic and binary liquids are studied numerically using a microscopic field theory for the evolution of the time-averaged atomic number density. A stochastic framework combining phase field crystal free…

材料科学 · 物理学 2015-05-27 Joel Berry , Martin Grant

Population dynamics and in particular microbial population dynamics, though they are complex but also intrinsically discrete and random, are conventionally represented as deterministic differential equations systems. We propose to revisit…

种群与进化 · 定量生物学 2014-06-02 Coralie Fritsch , Jérôme Harmand , Fabien Campillo

In this talk I discuss the general question of the portability of Molecular Dynamics codes for diffusive systems on parallel computers of the APE family. The intrinsic single precision arithmetics of the today available APE platforms does…

生物物理 · 物理学 2009-10-30 G. La Penna , S. Letardi , V. Minicozzi , S. Morante , G. C. Rossi , G. Salina

A variant of the Direct Simulation Monte Carlo method is used to study the behavior of a granular gas, in two and three dimensions, under varying density, restitution coefficient, and inelasticity regimes, for realistic vibrating wall…

介观与纳米尺度物理 · 物理学 2009-11-07 Welles A. M. Morgado , Eduardo R. Mucciolo

The study of granular crystals, metamaterials that consist of closely packed arrays of particles that interact elastically, is a vibrant area of research that combines ideas from disciplines such as materials science, nonlinear dynamics,…

斑图形成与孤子 · 物理学 2017-10-11 C. Chong , Mason A. Porter , P. G. Kevrekidis , C. Daraio

We have adapted classical molecular dynamics to study the structural and dynamical properties of amorphous silica surfaces. Concerning the structure, the density profile exhibits oscillations perpendicularly to the surface as observed in…

无序系统与神经网络 · 物理学 2009-11-07 M. Rarivomanantsoa , P. Jund , R. Jullien

Dynamic models are widely used to mathematically describe biological phenomena that evolve over time. One important area of application is leukaemia research, where leukaemia cells are genetically modified in preclinical studies to explore…

统计方法学 · 统计学 2026-02-02 Julian Wäsche , Romina Ludwig , Irmela Jeremias , Christiane Fuchs

We propose a novel computational strategy to study the glass transition of molecular fluids. Our approach combines the construction of simple yet realistic models with the development of Monte Carlo algorithms to accelerate equilibration…

统计力学 · 物理学 2026-03-31 Romain Simon , Jean-Louis Barrat , Ludovic Berthier

Event-driven molecular dynamics simulations are carried out on two rigid body systems which differ in the symmetry of their molecular mass distributions. First, simulations of methane in which the molecules interact via discontinuous…

The flow of granular material in a rotating cylinder was simulated by molecular dynamics in two dimensions using spherical as well as nonspherical grains. At very low but constant angular velocity we found that the flow varies irregularly…

凝聚态物理 · 物理学 2007-05-23 Thorsten Poeschel , Volkhard Buchholtz
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