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Cancer is a complex disease that is characterized by uncontrolled growth and division of cells. It involves a complex interplay between genetic and environmental factors that lead to the initiation and progression of tumors. Recent advances…

生物大分子 · 定量生物学 2025-02-07 Reza Bozorgpour

Molecular dynamics computer simulations are used to investigate thedynamics of a binary mixture of charged (Yukawa) particles with a size-ratio of 1:5. We find that the system undergoes a phase transition where the large particles…

无序系统与神经网络 · 物理学 2015-06-25 Norio Kikuchi , Juergen Horbach

Explicit simulations of fluid mixtures of highly size-dispersed particles are constrained by numerical challenges associated with identifying pair-interaction neighbors. Recent algorithmic developments have ameliorated these difficulties to…

软凝聚态物质 · 物理学 2022-12-07 Joseph M. Monti , Gary S. Grest

Much of our mechanistic understanding of the functions of biological macromolecules is based on static structural experiments, which can be modelled either as single structures or conformational ensembles. While these provide us with…

生物大分子 · 定量生物学 2025-10-02 Daria Gusew , Carl G. Henning Hansen , Kresten Lindorff-Larsen

Molecular dynamics (MD) simulations are used in biochemistry, physics, and other fields to study the motions, thermodynamic properties, and the interactions between molecules. Computational limitations and the complexity of these problems,…

数值分析 · 数学 2018-01-17 F. Grogan , M. Holst , L. Lindblom , R. Amaro

We propose a new model for the description of complex granular particles and their interaction in molecular dynamics simulations of granular material in two dimensions. The grains are composed of triangles which are connected by deformable…

材料科学 · 物理学 2007-05-23 Thorsten Poeschel , Volkhard Buchholtz

Molecular dynamics simulations are an important tool for describing the evolution of a chemical system with time. However, these simulations are inherently held back either by the prohibitive cost of accurate electronic structure theory…

化学物理 · 物理学 2018-12-20 Michael Gastegger , Philipp Marquetand

We propose a new model for the description of complex granular particles and their interaction in molecular dynamics simulations of granular material in two dimensions. The grains are composed of triangles which are connected by deformable…

adap-org · 物理学 2012-08-29 Thorsten Poeschel , Volkhard Buchholtz

A probabilistic discrete model for 2D protein crystal growth is presented. This model takes into account the available space and can describe growing processes of different nature due to the versatility of its parameters which gives the…

生物物理 · 物理学 2019-02-20 V. J. Bolós , R. Benítez , A. Eleta-López , J. L. Toca-Herrera

Molecular dynamics simulations use statistical mechanics at the atomistic scale to enable both the elucidation of fundamental mechanisms and the engineering of matter for desired tasks. The behavior of molecular systems at the microscale is…

计算物理 · 物理学 2020-12-25 Wujie Wang , Simon Axelrod , Rafael Gómez-Bombarelli

Along with recent progress in structural biology and genome biology, structural dynamics of molecular systems including nucleic acids has attracted attention in the context of gene regulation. Structure-function relationship is an important…

生物大分子 · 定量生物学 2021-11-23 Takeru Kameda , Akinori Awazu , Yuichi Togashi

We investigate the flow of granular material in a rotating cylinder numerically using molecular dynamics in two dimensions. The particles are described by a new model which allows to simulate geometrically complicated shaped grains. The…

材料科学 · 物理学 2015-06-24 Volkhard Buchholtz , Thorsten Poeschel , Hans-Juergen Tillemans

Molecular dynamics simulations have the potential to provide atomic-level detail and insight to important questions in chemical physics that cannot be observed in typical experiments. However, simply generating a long trajectory is…

化学物理 · 物理学 2015-06-22 Christian R. Schwantes , Robert T. McGibbon , Vijay S. Pande

Molecular Dynamics studies of chemical processes in solution are of great value in a wide spectrum of applications, which range from nano-technology to pharmaceutical chemistry. However, these calculations are affected by severe finite-size…

化学物理 · 物理学 2015-04-20 Claudio Perego , Matteo Salvalaglio , Michele Parrinello

An important aspect of astrophysical MHD turbulence research is developing diagnostics to connect simulations with the observable universe. Turbulent systems are by definition structurally complex in all fluid variables (density, velocity,…

天体物理学 · 物理学 2007-05-23 Eve C. Ostriker

Molecular Dynamics simulations are becoming a powerful tool for examining and predicting atomic and molecular processes in various environment. The present review shows how, in the fields of plasma physics, chemistry and interactions with…

等离子体物理 · 物理学 2023-12-14 Pascal Brault

We propose a simple microscopic model of molecular dynamics simulation to study orientational glass in three dimensions. We present simulation results for mixtures of mildly anisotropic particles and spherical impurities. We realize fcc…

软凝聚态物质 · 物理学 2012-10-29 Kyohei Takae , Akira Onuki

The nucleation of crystals in liquids is one of nature's most ubiquitous phenomena, playing an important role in areas such as climate change and the production of drugs. As the early stages of nucleation involve exceedingly small time and…

Molecular dynamics simulations are used to study structure formation in simple model polymer chains that are subject to excluded volume and torsional interactions. The changing conformations exhibited by chains of different lengths under…

软凝聚态物质 · 物理学 2009-11-07 D. C. Rapaport

We extend the phase field crystal model to accommodate exact atomic configurations and vacancies by requiring the order parameter to be non-negative. The resulting theory dictates the number of atoms and describes the motion of each of…

计算物理 · 物理学 2009-02-10 Pak Yuen Chan , Nigel Goldenfeld , Jon Dantzig
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