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The interplay of membrane proteins is vital for many biological processes, such as cellular transport, cell division, and signal transduction between nerve cells. Theoretical considerations have led to the idea that the membrane itself…

软凝聚态物质 · 物理学 2016-11-28 Casper van der Wel , Afshin Vahid , Anđela Šarić , Timon Idema , Doris Heinrich , Daniela J. Kraft

We investigate the strong curvature that appears at the boundaries of a thin crumpled elastic membrane. We account for these high-curvature regions in terms of the stretching-ridge singularity believed to dominate the structure of strongly…

软凝聚态物质 · 物理学 2008-11-23 T. A. Witten

Recent theoretical advances in elasticity of membranes following Helfrich's famous spontaneous curvature model are summarized in this review. The governing equations describing equilibrium configurations of lipid vesicles, lipid membranes…

软凝聚态物质 · 物理学 2017-07-27 Z. C. Tu , Z. C. Ou-Yang

A model describing cell membranes as optimal shapes with regard to the $L^2$-deficit of their mean curvature to a given constant called spontaneous curvature is considered. It is shown that the corresponding energy functional is lower…

微分几何 · 数学 2023-11-01 Christian Scharrer

An elastic membrane that is forced to reside in a container smaller than its natural size will deform and, upon further volume reduction, eventually crumple. The crumpled state is characterized by the localization of energy in a complex…

材料科学 · 物理学 2011-03-30 Paula Mellado , Shengfeng Cheng , Andres Concha

Using a combination of theory and experiments we study the interface between two immiscible domains in a colloidal membrane composed of rigid rods of different lengths. Geometric considerations of rigid rod packing imply that a domain of…

We investigate how an externally imposed curvature influences lipid segregation on two-phase-coexistent membranes. We show that the bending-modulus contrast of the two phases and the curvature act together to yield a reduced effective line…

软凝聚态物质 · 物理学 2018-06-21 Fangfu Ye , Robin L. B. Selinger , Jonathan V. Selinger

When a colloidal particle adheres to a fluid membrane, it induces elastic deformations in the membrane which oppose its own binding. The structural and energetic aspects of this balance are theoretically studied within the framework of a…

软凝聚态物质 · 物理学 2009-11-10 Markus Deserno

Cell-cell adhesion is established by specific binding of receptor and ligand proteins. The adhesion bonds attract each other and often aggregate into large clusters that are central to many biological processes. One possible origin of…

软凝聚态物质 · 物理学 2016-07-07 Nadiv Dharan , Oded Farago

A model of lipid bilayers made of a mixture of two lipids with different average compositions on both leaflets, is developed. A Landau hamiltonian describing the lipid-lipid interactions on each leaflet, with two lipidic fields $\psi_1$ and…

软凝聚态物质 · 物理学 2014-08-28 Guillaume Gueguen , Nicolas Destainville , Manoel Manghi

Common models for two-phase lipid bilayer membranes are based on an energy that consists of an elastic term for each lipid phase and a line energy at interfaces. Although such an energy controls only the length of interfaces, the membrane…

偏微分方程分析 · 数学 2016-03-10 Michael Helmers

Curvature in biological membranes can be generated by a variety of different molecular mechanisms such as protein scaffolding, lipid or protein asymmetry, cytoskeletal forces, etc. These mechanisms have the net effect of generating stresses…

The formation of microdomains, also called rafts, in biomembranes can be attributed to the surface tension of the membrane. In order to model this phenomenon, a model involving a coupling between the local composition and the local…

偏微分方程分析 · 数学 2016-06-29 Irene Fonseca , Gurgen Hayrapetyan , Giovanni Leoni , Barbara Zwicknagl

Adsorption of proteins onto membranes can alter the local membrane curvature. This phenomenon has been observed in biological processes such as endocytosis, tubulation and vesiculation. However, it is not clear how the local surface…

细胞行为 · 定量生物学 2016-04-28 Padmini Rangamani , Kranthi Kiran Mandadapu , George Oster

We study closed liquid membranes that segregate into three phases due to differences in the chemical and physical properties of its components. The shape and in-plane membrane arrangement of the phases are coupled through phase-specific…

软凝聚态物质 · 物理学 2012-08-17 Matthew F. Demers , Rastko Sknepnek , Monica Olvera de la Cruz

The electrostatic contribution to spontaneous membrane curvature is calculated within Poisson-Boltzmann theory under a variety of assumptions and emphasizing parameters in the physiological range. Asymmetric surface charges, either fixed…

凝聚态物理 · 物理学 2009-10-28 Tom Chou , Marko V. Jaric' , Eric D. Siggia

We theoretically study the elastic deformation of a fluid membrane induced by an adhering spherical colloidal particle within the framework of a Helfrich energy. Based on a full optimization of the membrane shape we find a continuous…

软凝聚态物质 · 物理学 2009-11-07 Markus Deserno , Thomas Bickel

Biological membranes are complex, dynamic structures essential for cellular compartmentalization, signaling, and mechanical integrity. The molecular organization of eukaryotic membranes has been extensively studied, including the lipid…

软凝聚态物质 · 物理学 2025-08-05 Nicolo Tormena , Teuta Pilizota , Kislon Voïtchovsky

We develop the elastic theory for inversion-asymmetric tethered membranes and use it to identify and study their possible phases. Asymmetry in a tethered membrane causes spontaneous curvature, which in general depends upon the local…

统计力学 · 物理学 2019-06-05 Tirthankar Banerjee , Niladri Sarkar , John Toner , Abhik Basu

A phenomenological Landau elasticity for the shape, dilation, and lipid-tilt of bilayer membranes is developed. The shape mode couples with the sum of the monolayers' tilt, while the dilation mode couples with the difference of the…

软凝聚态物质 · 物理学 2009-10-31 J. -B. Fournier
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