相关论文: Short-term Synaptic Depression Improves Error-corr…

Neurons and networks in the cerebral cortex must operate reliably despite multiple sources of noise. To evaluate the impact of both input and output noise, we determine the robustness of single-neuron stimulus selective responses, as well…

Neuronal spikes directly drive muscles and endow animals with agile movements, but applying the spike-based control signals to actuators in artificial sensor-motor systems inevitably causes a collapse of learning. We developed a system that…

Low-dimensional descriptions of neural network dynamics are an effective tool for bridging different scales of organization of brain structure and function. Recent advances in deriving mean-field descriptions for networks of coupled…

It is well known that a sparsely coded network in which the activity level is extremely low has intriguing equilibrium properties. In the present work, we study the dynamical properties of a neural network designed to store sparsely coded…

The problem of the transformation of microscopic information to the macroscopic level is an intriguing challenge in computational neuroscience, but also of general mathematical importance. Here, a phenomenological mathematical model is…

Diluted neural networks with continuous neurons and nonmonotonic transfer function are studied, with both fixed and dynamic synapses. A noisy stimulus with periodic variance results in a mechanism for controlling chaos in neural systems…

We introduce a weight update formula that is expressed only in terms of firing rates and their derivatives and that results in changes consistent with those associated with spike-timing dependent plasticity (STDP) rules and biological…

Deep learning has seen remarkable developments over the last years, many of them inspired by neuroscience. However, the main learning mechanism behind these advances - error backpropagation - appears to be at odds with neurobiology. Here,…

Anatomical studies demonstrate that brain reformats input information to generate reliable responses for performing computations. However, it remains unclear how neural circuits encode complex spatio-temporal patterns. We show that neural…

The interplay between excitatory and inhibitory neurons imparts rich functions of the brain. To understand the underlying synaptic mechanisms, a fundamental approach is to study the dynamics of excitatory and inhibitory conductances of each…

Short-term synaptic plasticity (STSP) affects the efficiency of synaptic transmission for persistent presynaptic activities. We consider attractor neural networks, for which the attractors are given, in the absence of STSP, by cell…

Synchronized oscillations in networks of inhibitory and excitatory coupled bursting neurons are common in a variety of neural systems from central pattern generators to human brain circuits. One example of the latter is the subcortical…

The studies described in this dissertation have attempted to address the cellular mechanisms of information storage by the brain. My work has focused primarily on the postsynaptic events that occur during and after induction of long-term…

Minimization of cortical prediction errors has been considered a key computational goal of the cerebral cortex underlying perception, action and learning. However, it is still unclear how the cortex should form and use information about…

Spiking neurons can perform spatiotemporal feature detection by nonlinear synaptic and dendritic integration of presynaptic spike patterns. Multicompartment models of non-linear dendrites and related neuromorphic circuit designs enable…

We consider a noise driven network of integrate-and-fire neurons. The network evolves as result of the activities of the neurons following spike-timing-dependent plasticity rules. We apply a self-consistent mean-field theory to the system…

It is shown that long term behavior of two connected Integrate- and- Fire neurons with excitatory synapses is determined by some fixed-points. In the case of equal synaptic weights four different dynamic phases are found. Between these…

In the mammalian brain newly acquired memories depend on the hippocampus for maintenance and recall, but over time these functions are taken over by the neocortex through a process called systems consolidation. However, reactivation of a…

The ability to effectively control brain dynamics holds great promise for the enhancement of cognitive function in humans, and the betterment of their quality of life. Yet, successfully controlling dynamics in neural systems is challenging,…

Epilepsy is a common neurological disorder characterized by abrupt seizures. Although seizures may appear random, they are often preceded by early warning signs in neural signals, notably, critical slowing down, a phenomenon in which the…