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Control problem in a biological system is the problem of finding an interventional policy for changing the state of the biological system from an undesirable state, e.g. disease, into a desirable healthy state. Boolean networks are utilized…

分子网络 · 定量生物学 2016-09-07 Mohammad Moradi , Sama Goliaei

Boolean networks are a popular modeling framework in computational biology to capture the dynamics of molecular networks, such as gene regulatory networks. It has been observed that many published models of such networks are defined by…

分子网络 · 定量生物学 2019-12-06 Elijah Paul , Gleb Pogudin , William Qin , Reinhard Laubenbacher

Percolation is an emblematic model to assess the robustness of interconnected systems when some of their components are corrupted. It is usually investigated in simple scenarios, such as the removal of the system's units in random order, or…

统计力学 · 物理学 2021-05-03 Oriol Artime , Manlio De Domenico

Recently, it has been claimed that some complex networks are self-similar under a convenient renormalization procedure. We present a general method to study renormalization flows in graphs. We find that the behavior of some variables under…

物理与社会 · 物理学 2009-11-13 Filippo Radicchi , José Javier Ramasco , Alain Barrat , Santo Fortunato

Datalog$^\neg$ is a central formalism used in a variety of domains ranging from deductive databases and abstract argumentation frameworks to answer set programming. Its model theory is the finite counterpart of the logical semantics…

计算机科学中的逻辑 · 计算机科学 2025-05-21 Van-Giang Trinh , Belaid Benhamou , Sylvain Soliman , François Fages

Percolation theory can be used to describe the structural properties of complex networks using the generating function formulation. This mapping assumes that the network is locally tree-like and does not contain short-range loops between…

物理与社会 · 物理学 2021-02-03 Peter Mann , V. Anne Smith , John B. O. Mitchell , Simon Dobson

Human decisional processes result from the employment of selected quantities of relevant information, generally synthesized from environmental incoming data and stored memories. Their main goal is the production of an appropriate and…

人工智能 · 计算机科学 2016-09-08 Graziano Barnabei , Franco Bagnoli , Ciro Conversano , Elena Lensi

Boolean networks are an important class of computational models for molecular interaction networks. Boolean canalization, a type of hierarchical clustering of the inputs of a Boolean function, has been extensively studied in the context of…

分子网络 · 定量生物学 2024-07-09 David Murrugarra , Elena S. Dimitrova

In previous works, we introduced the notion of dominant vertices in the context of dynamical systems on networks. This is a set of nodes in the underlying network whose evolution determines the whole network's dynamics after a transient…

动力系统 · 数学 2026-03-05 Andrea España , William Funez , Edgardo Ugalde

The co-evolution of network topology and dynamics is studied in an evolutionary Boolean network model that is a simple model of gene regulatory network. We find that a critical state emerges spontaneously resulting from interplay between…

统计力学 · 物理学 2007-05-23 Min Liu , Kevin E. Bassler

Boolean networks have been used successfully in modeling biological networks and provide a good framework for theoretical analysis. However, the analysis of large networks is not trivial. In order to simplify the analysis of such networks,…

分子网络 · 定量生物学 2013-11-29 Alan Veliz-Cuba , Reinhard Laubenbacher , Boris Aguilar

In this work, several random Boolean networks (RBN) are generated and analyzed from two characteristics: their time evolution diagram and their transition diagram. For this purpose, its randomness is estimated using three measures, of which…

信息论 · 计算机科学 2024-09-04 Manuel de J. Luevano , Alejandro Puga

I hypothesize that re-occurring prior experience of complex systems mobilizes a fast response, whose attractor is encoded by their strongly connected network core. In contrast, responses to novel stimuli are often slow and require the…

分子网络 · 定量生物学 2018-02-26 Peter Csermely

Floating-point neural networks dominate modern machine learning but incur substantial inference costs, motivating emerging interest in Boolean networks for resource-constrained deployments. Since Boolean networks use only Boolean…

人工智能 · 计算机科学 2026-05-13 Shengpu Wang , Yuhao Mao , Yani Zhang , Martin Vechev

One major open problem in network coding is to characterize the capacity region of a general multi-source multi-demand network. There are some existing computational tools for bounding the capacity of general networks, but their…

信息论 · 计算机科学 2015-03-17 Michelle Effros , Tracey Ho , Shirin Jalali

We study the phase diagram and the algorithmic hardness of the random `locked' constraint satisfaction problems, and compare them to the commonly studied 'non-locked' problems like satisfiability of boolean formulas or graph coloring. The…

无序系统与神经网络 · 物理学 2008-12-09 Lenka Zdeborová , Marc Mézard

Boolean networks are dynamical models of disease development in which the activation levels of genes are represented by binary variables. Given a Boolean network, controls represent mutations or medical treatments that fix the activation…

最优化与控制 · 数学 2026-04-02 Kyungduk Moon , Kangbok Lee , Loïc Paulevé

A reflection of our ultimate understanding of a complex system is our ability to control its behavior. Typically, control has multiple prerequisites: It requires an accurate map of the network that governs the interactions between the…

系统与控制 · 计算机科学 2016-09-21 Yang-Yu Liu , Albert-Laszló Barabási

We investigate the expressive power of neural networks from the point of view of descriptive complexity. We study neural networks that use floating-point numbers and piecewise polynomial activation functions from two perspectives: 1) the…

计算复杂性 · 计算机科学 2025-05-12 Veeti Ahvonen , Damian Heiman , Antti Kuusisto

Complex networks are a powerful paradigm to model complex systems. Specific network models, e.g., multilayer networks, temporal networks, and signed networks, enrich the standard network representation with additional information to better…

数据结构与算法 · 计算机科学 2019-06-05 Edoardo Galimberti