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Although the survival rate of cancer patients has significantly increased due to advances in anti-cancer therapeutics, one of the major side effects of these therapies, particularly radiotherapy, is the potential manifestation of…

定量方法 · 定量生物学 2014-11-07 Kamran Kaveh , Venkata S. K. Manem , Mohammad Kohandel , Siv Sivaloganathan

Thin elastic sheets appear in systems ranging from graphene to biological membranes, where phenomena such as wrinkling, folding, and thermal fluctuations originate from geometric nonlinearities. These effects are treated within weakly…

软凝聚态物质 · 物理学 2025-12-04 Yael Cohen , Animesh Pandey , Yafei Zhang , Cy Maor , Michael Moshe

We survey the recent mathematical results about aging in certain simple disordered models. We start by the Bouchaud trap model. We then survey the results obtained for simple models of spin-glass dynamics, like the REM (the Random Energy…

概率论 · 数学 2007-05-23 Gérard Ben-Arous

Surfaces eroded by ion-sputtering are sometimes observed to develop morphologies which are either ripple (periodic), or rough (non-periodic). We introduce a discrete stochastic model that allows us to interpret these experimental…

凝聚态物理 · 物理学 2009-10-28 Rodolfo Cuerno , Hernan A. Makse , Silvina Tomassone , Stephen T. Harrington , H. E. Stanley

The theories of stochastic quantum mechanics and stochastic electrodynamics bring to light important aspects of the quantum dynamics that are concealed in the standard formalism. Here we take further previous work regarding the connection…

量子物理 · 物理学 2021-04-28 A. M. Cetto , L. de la Peña , A. Valdés-Hernández

The generation of entanglement produced by a local potential interaction in a bipartite system is investigated. The degree of entanglement is contrasted with the underlying classical dynamics for a Rydberg molecule (a charged particle…

量子物理 · 物理学 2007-05-23 M. Lombardi , A. Matzkin

The simulation of transmission electron microscopy (TEM) images or diffraction patterns is often required to interpret their contrast and extract specimen features. This is especially true for high-resolution phase-contrast imaging of…

材料科学 · 物理学 2021-03-30 Jacob Madsen , Timothy J. Pennycook , Toma Susi

We describe a new phenomenon in models of coalescence and fragmentation, that of gel-shatter cycles. These are dynamical, unforced, stochastic cycles in which slow, approximately deterministic coalescence up to and beyond gelation is…

动力系统 · 数学 2021-05-26 Brennen T. Fagan , Niall J. MacKay , Dmitri O. Pushkin , A. Jamie Wood

The paper presents a computational stochastic model of virtual cells irradiation, based on Quasi-Markov Chain Monte Carlo method and using biophysical input. The model is based on a stochastic tree of probabilities for each cell of the…

生物物理 · 物理学 2014-12-23 Krzysztof Wojciech Fornalski

In quantum many-body systems, measurements can induce qualitative new features, but their simulation is hindered by the exponential complexity involved in sampling the measurement results. We propose to use machine learning to assist the…

量子物理 · 物理学 2024-12-03 Yuchen Zhu , Molei Tao , Yuebo Jin , Xie Chen

Purpose of review: The epithelial-Mesenchymal Transition (EMT) and the generation of Cancer Stem Cells (CSC) are two fundamental aspects contributing to tumor growth, acquisition of resistance to therapy, formation of metastases, and tumor…

分子网络 · 定量生物学 2018-11-07 Federico Bocci , Herbert Levine , José Nelson Onuchic , Mohit Kumar Jolly

A stochastic genetic model for biological aging is introduced bridging the gap between the bit-string Penna model and the Pletcher-Neuhauser approach. The phenomenon of exponentially increasing mortality function at intermediate ages and…

统计力学 · 物理学 2007-05-23 Zhi-Feng Huang , Dietrich Stauffer

Single-cell gene expression measurements encode variability spanning molecular noise, cell-to-cell heterogeneity, and technical artifacts. Mechanistic stochastic models provide powerful approaches to disentangle these sources, yet inferring…

定量方法 · 定量生物学 2025-09-19 Christopher E. Miles

We study time continuous branching processes with exponentially distributed lifetimes, with two types of cells that proliferate according to binary fission. A range of possible system dynamics are considered, each of which is characterized…

概率论 · 数学 2022-04-27 Nam H Nguyen , Marek Kimmel

Pinning particles at random in supercooled liquids is a promising route to make substantial progress on the glass transition problem. Here we develop a mean-field theory by studying the equilibrium and non-equilibrium dynamics of the…

无序系统与神经网络 · 物理学 2012-12-18 Chiara Cammarota , Giulio Biroli

Under rapid undercooling, glass forming liquids freeze in an amorphous state that can equilibrate only on enormously long time-scales, This is the characteristic sign of aging, which has been observed in a wide range of systems. Brownian…

The concepts and methods used for the study of disordered systems have proven useful in the analysis of the evolution equations of quantum chromodynamics in the high-energy regime: Indeed, parton branching in the semi-classical…

高能物理 - 唯象学 · 物理学 2015-07-06 Stephane Munier

The mortality rate of many complex multicellular organisms increase with age, which suggests that net aging damage is accumulative, despite remodeling processes. But how exactly do little mishaps in the cellular level accumulate and spread…

组织与器官 · 定量生物学 2017-12-12 Daniel Suma , Aylin Acun , Pinar Zorlutuna , Dervis Can Vural

Aging, as defined in terms of the slope of the probability of death versus time (hazard curve), is a generic phenomenon observed in nearly all complex systems. Theoretical models of aging predict hazard curves that monotonically increase in…

生物物理 · 物理学 2023-12-20 Cagatay Eskin , Dervis C. Vural

We revisit the classic problem of elastic cavitation within the framework of stochastic elasticity. For the deterministic elastic problem, involving homogeneous isotropic incompressible hyperelastic spheres under radially symmetric tension,…

软凝聚态物质 · 物理学 2019-08-13 L. Angela Mihai , Danielle Fitt , Thomas E. Woolley , Alain Goriely