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We theoretically consider specific adhesion of a fluctuating membrane to a hard substrate via the formation of bonds between receptors attached to the substrate and ligands in the membrane. By integrating out the degrees of freedom of the…

软凝聚态物质 · 物理学 2010-10-13 Thomas Speck , Ellen Reister , Udo Seifert

Based on a microscopic density functional theory we investigate the morphology of thin liquidlike wetting films adsorbed on substrates endowed with well-defined chemical heterogeneities. As paradigmatic cases we focus on a single chemical…

软凝聚态物质 · 物理学 2009-10-31 C. Bauer , S. Dietrich

A self-consistent model is developed to investigate attachment / detachment kinetics of two soft, deformable microspheres with irregular surface and coated with flexible binding ligands. The model highlights how the microscale binding…

细胞行为 · 定量生物学 2015-10-13 Sarthok Sircar , Andrei Kotousov , Giang Nguyen , Anthony J. Roberts

Consider a surface described by a Hamiltonian which depends only on the metric and extrinsic curvature induced on the surface. The metric and the curvature, along with the basis vectors which connect them to the embedding functions defining…

数学物理 · 物理学 2009-11-10 Jemal Guven

We investigate theoretically the adhesion and electronic properties of graphene on a muscovite mica surface using the density functional theory (DFT) with van der Waals (vdW) interactions taken into account (the vdW-DF approach). We found…

介观与纳米尺度物理 · 物理学 2011-01-25 A. N. Rudenko , F. J. Keil , M. I. Katsnelson , A. I. Lichtenstein

Various adhesion mechanisms that have been understood in the field of synthetic adhesives are described and these are linked with situations relevant to fouling issues. The review mainly deals with mechanical aspects of adhesion phenomena,…

软凝聚态物质 · 物理学 2016-04-13 Cyprien Gay

Interactions mediated by the cell membrane between inclusions, such as membrane proteins or antimicrobial peptides, play important roles in their biological activity. They also constitute a fascinating challenge for physicists, since they…

生物物理 · 物理学 2019-03-15 Anne-Florence Bitbol , Doru Constantin , Jean-Baptiste Fournier

We consider a theoretical model for membranes with adhesive receptors, or stickers, that are actively switched between two conformational states. In their 'on'-state, the stickers bind to ligands in an apposing membrane, whereas they do not…

软凝聚态物质 · 物理学 2007-05-23 Bartosz Rozycki , Reinhard Lipowsky , Thomas R. Weikl

Path-integral molecular dynamics simulations based on density functional theory employing exchange-correlation density functionals capable of treating nonlocal van der Waals (vdW) interactions self-consistently provide a remarkably accurate…

化学物理 · 物理学 2014-02-13 Jeffrey M. McMahon , Miguel A. Morales , Brian Kolb , Timo Thonhauser

When sheets of layered material like C, WS$_2$ or BN are restricted to finite sizes, they generally form single- and multi-walled hollow nanoparticles in order to avoid dangling bonds. Using continuum approaches to model elastic deformation…

软凝聚态物质 · 物理学 2007-05-23 U. S. Schwarz , S. A. Safran , S. Komura

We study the interaction between capillary forces and deformation in the context of a deformable capillary adhesive: a clamped, tense membrane is adhered to a rigid substrate by the surface tension of a liquid droplet. We find that the…

流体动力学 · 物理学 2019-03-20 Matthew Butler , Finn Box , Thomas Robert , Dominic Vella

Graphene, the 2D form of carbon, has excellent mechanical, electrical and thermal properties and a variety of potential applications including NEMS, protective coatings, transparent electrodes in display devices and biological applications.…

介观与纳米尺度物理 · 物理学 2018-08-20 Narasimha G Boddeti , Rong Long , Martin L Dunn

Unraveling the relation between the chemical structure of small drug-like compounds and their rate of passive permeation across lipid membranes is of fundamental importance for pharmaceutical applications. The elucidation of a comprehensive…

化学物理 · 物理学 2018-12-31 Roberto Menichetti , Kiran H. Kanekal , Tristan Bereau

We have studied the adsorption kinetics of the protein amylase at solid/liquid interfaces. Offering substrates with tailored properties, we are able to separate the impact of short- and long-range interactions. By means of a colloidal Monte…

软凝聚态物质 · 物理学 2007-05-23 Anthony Quinn , Hubert Mantz , Karin Jacobs , Markus Bellion , Ludger Santen

The adhesion of biomembranes is mediated by the binding of membrane-anchored receptor and ligand proteins. The proteins can only bind if the separation between apposing membranes is sufficiently close to the length of the protein complexes,…

亚细胞过程 · 定量生物学 2019-11-22 Thomas R. Weikl , Jinglei Hu , Batuhan Kav , Bartosz Rozycki

We develop a framework to understand the mechanics of metamaterial sheets on curved surfaces. Here we have constructed a continuum elastic theory of mechanical metamaterials by introducing an auxiliary, scalar gauge-like field that absorbs…

软凝聚态物质 · 物理学 2023-11-02 Sourav Roy , C. D. Santangelo

The adsorption of a collagen fragment on both a hydrophobic, hydrogen-terminated and a hydrophilic, natively oxidised Si surface is investigated using all-atom molecular dynamics. While favourable direct protein-surface interactions via…

软凝聚态物质 · 物理学 2019-03-27 Daniel J. Cole , Mike C. Payne , Lucio Colombi Ciacchi

We investigate theoretically the morphology of a thin nematic film adsorbed at flat substrate patterned by stripes with alternating aligning properties, normal and tangential respectively. We construct a simple "exactly-solvable" effective…

软凝聚态物质 · 物理学 2017-02-01 Nuno M. Silvestre , Margarida M. Telo da Gama , Mykola Tasinkevych

Shapes of biological membranes are dynamically regulated in living cells. Although membrane shape deformation by proteins at thermal equilibrium has been extensively studied, nonequilibrium dynamics have been much less explored. Recently,…

生物物理 · 物理学 2020-11-19 Naoki Tamemoto , Hiroshi Noguchi

Recently, a simple and elegant "dimple" model was introduced by McMeeking et al. (Adv Eng Mat 12(5), 389-397, 2010) to show a mechanism for a bistable adhesive system involving a surface with a shallow depression. The system shows, at least…

材料科学 · 物理学 2017-01-17 Michele Ciavarella , Antonio Papangelo