相关论文: Coevolution of membranes and channels: A possible …

In this paper we review and extend our earlier recent work on thermostated systems. A description of nano-biological systems by Markov chains in coordinate space in the strongly overdamped limit is presented. Characterization of the most…

Life demonstrates remarkable homochirality of its major building blocks: nucleic acids, amino acids, sugars, and phospholipids. We propose a mechanism that places the root of life homochirality in the formation of phospholipid bilayer…

Many models for the origin of life have focused on understanding how evolution can drive the refinement of a preexisting enzyme, such as the evolution of efficient replicase activity. Here we present a model for what was, arguably, an even…

The original hypothesis about Three-stage origin of life (TOL) on the Earth is developed and discussed. The role of the temperature factor in life origin is considered. It is supposed, that three stages of abiogenesis (DNA world, RNA world…

It is argued that all notions associated with the origin of life should be related with the participatory anthropic principle of Wheeler and must be extended into the realm of the multiverse. Also discussed is the notion that life can only…

The emergence of self-replication and information transmission in life's origin remains unexplained despite extensive research on the topic. A hypothesis explaining the transition from a simple organic world to a complex RNA world is…

Although it has been notoriously difficult to pin down precisely what it is that makes life so distinctive and remarkable, there is general agreement that its informational aspect is one key property, perhaps the key property. The unique…

Understanding the origin(s) of life (OoL) is a fundamental challenge for science in the 21st century. Research on OoL spans many disciplines, including chemistry, physics, biology, planetary sciences, computer science, mathematics and…

Since the Hadean era of Earth's history, peptides/proteins and RNA have undergone a complex evolutionary trajectory. Originating from simple monomeric units, these molecules evolved abiotically under various biochemical and biophysical…

Despite great advances in our understanding of the formation of the Solar System, the evolution of the Earth, and the chemical basis for life, we are not much closer than the ancient Greeks to an answer of whether life has arisen and…

After Earth's origin, our host star, the Sun, was shining 20 to 25 percent less brightly than today. Without greenhouse-like conditions to warm the atmosphere, our early planet would have been an ice ball and life may never have evolved.…

We survey some of the philosophical challenges and pitfalls within origins research. Several of these challenges exhibit circularities, paradoxes, or anthropic biases. We present origins approaches in terms of three broad categories:…

The study of origins of life on Earth and the search for life on other planets are closely linked. Prebiotic chemical scenarios can help prioritize planets as targets for the search for life as we know it and can provide informative priors…

The origin of life must have been preceded by Darwin-like evolutionary dynamics that could propagate it. How did that adaptive dynamics arise? And from what prebiotic molecules? Using evolutionary invasion analysis, we develop a universal…

For more than 3.5 billion years, life experienced dramatic environmental extremes on Earth. These include shifts from oxygen-less to over-oxygenated atmospheres and cycling between hothouse conditions and global glaciations. Meanwhile, an…

The concept of evolutionary development of structures constituted a \emph{real} revolution in biology: it was possible to understand how the very complex structures of life can arise in an out-of-equilibrium system. The investigation of…

The RNA World hypothesis predicts that self-replicating RNAs evolved before DNA genomes and coded proteins. Despite widespread support for the RNA World, self-replicating RNAs have yet to be identified in a natural context, leaving a key…

A modified version of panspermia theory, named Nebula-Relay hypothesis or local panspermia, is introduced to explain the origin of life on Earth. Primitive life, acting as the seeds of life on Earth, originated at pre-solar epoch through…

Through in-depth thinking and reasoning about the conditions required for cells to maintain unchanged material distribution, it is concluded that life metabolic reactions require high information content. However, the self-replication of a…

The simplest possible beginning of abiogenesis has been a riddle from the last century, which is most successfully solved by the Lipid World hypothesis. However, origin of the next stages of evolution starting form lipids is still in dark.…