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It is often of interest to study the association between covariates and the cumulative incidence of a right-censored time-to-event outcome. When time-varying covariates are measured on a fixed discrete time scale, it is desirable to account…

统计方法学 · 统计学 2026-04-28 Hongxiang Qiu , Marco Carone , Alex Luedtke , Peter B. Gilbert

Instrumental variable methods provide a powerful approach to estimating causal effects in the presence of unobserved confounding. But a key challenge when applying them is the reliance on untestable "exclusion" assumptions that rule out any…

统计方法学 · 统计学 2020-06-23 Jason Hartford , Victor Veitch , Dhanya Sridhar , Kevin Leyton-Brown

This article studies the estimation of the causal effect of a time-varying treatment on time-to-an-event or on some other continuously distributed outcome. The paper applies to the situation where treatment is repeatedly adapted to…

统计理论 · 数学 2008-06-19 Judith J. Lok

Causal inference from longitudinal observational data is a challenging problem due to the difficulty in correctly identifying the time-dependent confounders, especially in the presence of latent time-dependent confounders. Instrumental…

机器学习 · 计算机科学 2023-12-13 Debo Cheng , Ziqi Xu , Jiuyong Li , Lin Liu , Jixue Liu , Wentao Gao , Thuc Duy Le

The study of causality or causal inference - how much a given treatment causally affects a given outcome in a population - goes way beyond correlation or association analysis of variables, and is critical in making sound data driven…

数据库 · 计算机科学 2017-08-09 Sudeepa Roy , Babak Salimi

Adapting to latent confounded shift remains a core challenge in modern AI. This setting is driven by hidden variables that induce spurious correlations between inputs and outputs during training, leading models to rely on non-causal…

机器学习 · 计算机科学 2026-05-14 Jialin Yu , Yuxiang Zhou , Haoxuan Li , Junchi Yu , Mengyue Yang , Yulan He , Nevin L. Zhang , Philip Torr , Ricardo Silva

We study the identification of causal effects in the presence of different types of constraints (e.g., logical constraints) in addition to the causal graph. These constraints impose restrictions on the models (parameterizations) induced by…

人工智能 · 计算机科学 2025-10-15 Yizuo Chen , Adnan Darwiche

Instrumental variables allow for quantification of cause and effect relationships even in the absence of interventions. To achieve this, a number of causal assumptions must be met, the most important of which is the independence assumption,…

机器学习 · 统计学 2021-11-05 Nikolai Miklin , Mariami Gachechiladze , George Moreno , Rafael Chaves

This paper studies causal discovery in irregularly sampled time series-a key challenge in risk-sensitive domains like finance, healthcare, and climate science, where missing data and inconsistent sampling frequencies distort causal…

机器学习 · 计算机科学 2026-05-12 Weihong Li , Baohong Li , Anpeng Wu , Zhihan Li , Ming Ma , Keting Yin , Kun Kuang

Counterfactual inference aims to answer retrospective "what if" questions and thus belongs to the most fine-grained type of inference in Pearl's causality ladder. Existing methods for counterfactual inference with continuous outcomes aim at…

机器学习 · 统计学 2024-01-12 Valentyn Melnychuk , Dennis Frauen , Stefan Feuerriegel

Quantifying cause and effect relationships is an important problem in many domains. The gold standard solution is to conduct a randomised controlled trial. However, in many situations such trials cannot be performed. In the absence of such…

统计方法学 · 统计学 2023-01-19 Jakob Zeitler , Athanasios Vlontzos , Ciaran M. Gilligan-Lee

Delayed outcomes are ubiquitous in online experimentation. When such a temporal dimension is present, treatment influences not only the outcome value but also the outcome timing, which can move in opposite directions. Motivated by the…

统计方法学 · 统计学 2026-03-30 Michael Lindon , Nathan Kallus

Foundation models for structured time series data must contend with a fundamental challenge: observations often conflate the true underlying physical phenomena with systematic distortions introduced by measurement instruments. This…

机器学习 · 计算机科学 2025-07-09 Jeroen Audenaert , Daniel Muthukrishna , Paul F. Gregory , David W. Hogg , V. Ashley Villar

We propose and implement an approach to inference in linear instrumental variables models which is simultaneously robust and computationally tractable. Inference is based on self-normalization of sample moment conditions, and allows for…

计量经济学 · 经济学 2022-11-29 Eric Gautier , Christiern Rose

Model-free time-to-event regression under confounding presents challenges due to biases introduced by causal and censoring sampling mechanisms. This phenomenology poses problems for classical non-parametric estimators like Beran's or the…

统计理论 · 数学 2025-02-28 Carlos García-Meixide , Marcos Matabuena

We introduce new inference procedures for counterfactual and synthetic control methods for policy evaluation. We recast the causal inference problem as a counterfactual prediction and a structural breaks testing problem. This allows us to…

计量经济学 · 经济学 2022-01-26 Victor Chernozhukov , Kaspar Wüthrich , Yinchu Zhu

Survival analysis is a fundamental area of focus in biomedical research, particularly in the context of personalized medicine. This prominence is due to the increasing prevalence of large and high-dimensional datasets, such as omics and…

机器学习 · 统计学 2024-08-23 Carlos García Meixide , Marcos Matabuena , Louis Abraham , Michael R. Kosorok

Causal inference is central to many areas of artificial intelligence, including complex reasoning, planning, knowledge-base construction, robotics, explanation, and fairness. An active community of researchers develops and enhances…

人工智能 · 计算机科学 2019-11-05 Amanda Gentzel , Dan Garant , David Jensen

To draw real-world evidence about the comparative effectiveness of multiple time-varying treatments on patient survival, we develop a joint marginal structural survival model and a novel weighting strategy to account for time-varying…

统计方法学 · 统计学 2023-08-08 Liangyuan Hu , Jiayi Ji , Himanshu Joshi , Erick Scott , Fan Li

Causal inference is known to be very challenging when only observational data are available. Randomized experiments are often costly and impractical and in instrumental variable regression the number of instruments has to exceed the number…

统计方法学 · 统计学 2018-06-19 Dominik Rothenhäusler , Peter Bühlmann , Nicolai Meinshausen