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Recent progress in deep learning is revolutionizing the healthcare domain including providing solutions to medication recommendations, especially recommending medication combination for patients with complex health conditions. Existing…

人工智能 · 计算机科学 2019-03-08 Junyuan Shang , Cao Xiao , Tengfei Ma , Hongyan Li , Jimeng Sun

In the past decade, with the development of big data technology, an increasing amount of patient information has been stored as electronic health records (EHRs). Leveraging these data, various doctor recommendation systems have been…

信息检索 · 计算机科学 2022-07-14 Luning Bi , Yunlong Wang , Fan Zhang , Zhuqing Liu , Yong Cai , Emily Zhao

With the growing imbalance between limited medical resources and escalating demands, AI-based clinical tasks have become paramount. As a sub-domain, medication recommendation aims to amalgamate longitudinal patient history with medical…

人工智能 · 计算机科学 2023-11-28 Xiang Li , Shunpan Liang , Yulei Hou , Tengfei Ma

Drug combinations can cause adverse drug-drug interactions(DDIs). Identifying specific effects is crucial for developing safer therapies. Previous works on DDI event prediction have typically been limited to using labels of specific events…

生物大分子 · 定量生物学 2024-11-05 Yingying Wang , Yun Xiong , Xixi Wu , Xiangguo Sun , Jiawei Zhang

Predicting medications is a crucial task in many intelligent healthcare systems. It can assist doctors in making informed medication decisions for patients according to electronic medical records (EMRs). However, medication prediction is a…

人工智能 · 计算机科学 2022-05-02 Yang An , Bo Jin , Xiaopeng Wei

Polypharmacy, defined as the use of multiple drugs together, is a standard treatment method, especially for severe and chronic diseases. However, using multiple drugs together may cause interactions between drugs. Drug-drug interaction…

机器学习 · 计算机科学 2022-07-13 Farhan Tanvir , Khaled Mohammed Saifuddin , Esra Akbas

Medication recommendation using Electronic Health Records (EHR) is challenging due to complex medical data. Current approaches extract longitudinal information from patient EHR to personalize recommendations. However, existing models often…

机器学习 · 计算机科学 2023-09-27 Jiacong Mi , Yi Zu , Zhuoyuan Wang , Jieyue He

Extensive adoption of electronic health records (EHRs) offers opportunities for their use in various downstream clinical analyses. To accomplish this purpose, enriching an EHR cohort with external knowledge (e.g., standardized medical…

机器学习 · 计算机科学 2024-06-13 Ahmad Wisnu Mulyadi , Heung-Il Suk

Medication Recommendation (MR) is a promising research topic which booms diverse applications in the healthcare and clinical domains. However, existing methods mainly rely on sequential modeling and static graphs for representation…

机器学习 · 计算机科学 2025-01-16 Guanlin Liu , Xiaomei Yu , Zihao Liu , Xue Li , Xingxu Fan , Xiangwei Zheng

Medication recommendation is an essential task of AI for healthcare. Existing works focused on recommending drug combinations for patients with complex health conditions solely based on their electronic health records. Thus, they have the…

机器学习 · 计算机科学 2022-07-20 Chaoqi Yang , Cao Xiao , Fenglong Ma , Lucas Glass , Jimeng Sun

While Graph Neural Networks have gained popularity in multiple domains, graph-structured input remains a major challenge due to (a) over-smoothing, (b) noisy neighbours (heterophily), and (c) the suspended animation problem. To address all…

机器学习 · 计算机科学 2021-10-27 Gayan K. Kulatilleke , Marius Portmann , Ryan Ko , Shekhar S. Chandra

Recent advances and achievements of artificial intelligence (AI) as well as deep and graph learning models have established their usefulness in biomedical applications, especially in drug-drug interactions (DDIs). DDIs refer to a change in…

Drug combination therapy has become a increasingly promising method in the treatment of cancer. However, the number of possible drug combinations is so huge that it is hard to screen synergistic drug combinations through wet-lab…

机器学习 · 计算机科学 2021-07-07 J. Wang , X. Liu , S. Shen , L. Deng , H. Liu*

Medication recommendation systems play a crucial role in assisting clinicians with personalized treatment decisions. While existing approaches have made significant progress in learning medication representations, they suffer from two…

机器学习 · 计算机科学 2025-11-19 Kelin Ren , Chan-Yang Ju , Dong-Ho Lee

Medication recommendations aim to generate safe and effective medication sets from health records. However, accurately recommending medications hinges on inferring a patient's latent clinical condition from sparse and noisy observations,…

信息检索 · 计算机科学 2026-03-20 Xiangxu Zhang , Xiao Zhou , Hongteng Xu , Jianxun Lian

Clinical predictive models often rely on patients' electronic health records (EHR), but integrating medical knowledge to enhance predictions and decision-making is challenging. This is because personalized predictions require personalized…

人工智能 · 计算机科学 2024-01-19 Pengcheng Jiang , Cao Xiao , Adam Cross , Jimeng Sun

This paper addresses the challenges posed by the unstructured nature and high-dimensional semantic complexity of electronic health record texts. A deep learning method based on attention mechanisms is proposed to achieve unified modeling…

计算与语言 · 计算机科学 2025-07-03 Ting Xu , Xiaoxiao Deng , Xiandong Meng , Haifeng Yang , Yan Wu

Learning from longitudinal electronic health records is limited if it does not capture the temporal trajectories of the patient's state in a clinical setting. Graph models allow us to capture the hidden dependencies of the multivariate…

机器学习 · 计算机科学 2025-03-31 Munib Mesinovic , Soheila Molaei , Peter Watkinson , Tingting Zhu

Interference between pharmacological substances can cause serious medical injuries. Correctly predicting so-called drug-drug interactions (DDI) does not only reduce these cases but can also result in a reduction of drug development cost.…

机器学习 · 计算机科学 2019-08-06 Md. Rezaul Karim , Michael Cochez , Joao Bosco Jares , Mamtaz Uddin , Oya Beyan , Stefan Decker

Medication recommendation is a crucial task for intelligent healthcare systems. Previous studies mainly recommend medications with electronic health records (EHRs). However, some details of interactions between doctors and patients may be…

计算与语言 · 计算机科学 2022-09-16 Zhenfeng He , Yuqiang Han , Zhenqiu Ouyang , Wei Gao , Hongxu Chen , Guandong Xu , Jian Wu
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