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Network Meta-Analysis (NMA) plays a pivotal role in synthesizing evidence from various sources and comparing multiple interventions. At its core, NMA relies on integrating both direct evidence from head-to-head comparisons and indirect…

Network meta-analysis (NMA) is widely used to compare multiple interventions simultaneously by synthesizing direct and indirect evidence. The general fixed or random effects contrast-based NMA model can be applied to different outcomes and…

统计方法学 · 统计学 2026-03-03 Harlan Campbell , Jeroen P. Jansen

Network meta-analysis (NMA) allow combining efficacy information from multiple comparisons from trials assessing different therapeutic interventions for a given disease and to estimate unobserved comparisons from a network of observed…

统计方法学 · 统计学 2016-04-08 Victoria Nyaga , Marc Aerts , Marc Arbyn

Network meta-analysis (NMA) is a technique used in medical statistics to combine evidence from multiple medical trials. NMA defines an inference and information processing problem on a network of treatment options and trials connecting the…

统计力学 · 物理学 2022-11-30 Annabel L. Davies , Tobias Galla

In network meta-analysis (NMA), we synthesize all relevant evidence about health outcomes with competing treatments. The evidence may come from randomized controlled trials (RCT) or non-randomized studies (NRS) as individual participant…

Component network meta-analysis (CNMA) is a statistical methodology that enables estimation of relative effects for multi-component treatments, such as combinations of antidepressants, and individual components, such as single…

统计方法学 · 统计学 2026-05-15 Augustine Wigle , Audrey Béliveau , Adriani Nikolakopoulou , Lifeng Lin

Network meta-analysis (NMA) is a useful tool to compare multiple interventions simultaneously in a single meta-analysis, it can be very helpful for medical decision making when the study aims to find the best therapy among several active…

统计方法学 · 统计学 2024-02-02 Ao Huang , Yi Zhou , Satoshi Hattori

Network meta-analysis (NMA) usually provides estimates of the relative effects with the highest possible precision. However, sparse networks with few available studies and limited direct evidence can arise, threatening the robustness and…

The reliability of the results of network meta-analysis (NMA) lies in the plausibility of key assumption of transitivity. This assumption implies that the effect modifiers' distribution is similar across treatment comparisons. Transitivity…

统计方法学 · 统计学 2023-10-06 Georgios Seitidis , Stavros Nikolakopoulos , Ioannis Ntzoufras , Dimitris Mavridis

Deep learning-based models have demonstrated remarkable success in solving illposed inverse problems; however, many fail to strictly adhere to the physical constraints imposed by the measurement process. In this work, we introduce a…

机器学习 · 计算机科学 2025-05-22 Jorge Bacca

Component network meta-analysis (CNMA) models are an extension of standard network meta-analysis (NMA) models which account for the use of multicomponent treatments in the network. This article contributes innovatively to several…

统计方法学 · 统计学 2025-07-23 Augustine Wigle , Audrey Béliveau

A key output of network meta-analysis (NMA) is the relative ranking of treatments; nevertheless, it has attracted substantial criticism. Existing ranking methods often lack clear interpretability and fail to adequately account for…

The strength of association between a pair of data vectors is represented by a nonnegative real number, called matching weight. For dimensionality reduction, we consider a linear transformation of data vectors, and define a matching error…

机器学习 · 统计学 2015-12-15 Hidetoshi Shimodaira

Network Meta-Analysis (NMA) is an increasingly popular evidence synthesis tool that can provide a ranking of competing treatments, also known as a treatment hierarchy. Treatment-Covariate Interactions (TCIs) can be included in NMA models to…

统计方法学 · 统计学 2026-05-13 Augustine Wigle , Erica E. M. Moodie

Causal mediation analysis (CMA) is a powerful method to dissect the total effect of a treatment into direct and mediated effects within the potential outcome framework. This is important in many scientific applications to identify the…

机器学习 · 计算机科学 2023-06-14 Ziyang Jiang , Yiling Liu , Michael H. Klein , Ahmed Aloui , Yiman Ren , Keyu Li , Vahid Tarokh , David Carlson

Network meta-analysis (NMA) is widely used in healthcare decision-making, where estimates of the effect of multiple treatments on outcomes are required. For time-to-event outcomes such as survival or disease progression the most common…

统计方法学 · 统计学 2025-09-15 David M. Phillippo , Ayman Sadek , Hugo Pedder , Nicky J. Welton

Similarity measures are widely used to interpret the representational geometries used by neural networks to solve tasks. Yet, because existing methods compare the extrinsic geometry of representations in state space, rather than their…

机器学习 · 计算机科学 2026-04-03 N Alex Cayco-Gajic , Arthur Pellegrino

Several automatic approaches for objective music performance assessment (MPA) have been proposed in the past, however, existing systems are not yet capable of reliably predicting ratings with the same accuracy as professional judges. This…

声音 · 计算机科学 2021-08-16 Pavan Seshadri , Alexander Lerch

Estimating treatment effects from observational data is challenging due to two main reasons: (a) hidden confounding, and (b) covariate mismatch (control and treatment groups not having identical distributions). Long lines of works exist…

机器学习 · 计算机科学 2025-04-30 Praharsh Nanavati , Ranjitha Prasad , Karthikeyan Shanmugam

There has been a transition from broad to more specific research questions in the practice of network meta-analysis (NMA). Such convergence is also taking place in the context of individual registrational trials, following the recent…

应用统计 · 统计学 2026-05-07 Antonio Remiro-Azócar , Anders Gorst-Rasmussen
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