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Estimating individualised treatment effect (ITE) -- that is the causal effect of a set of variables (also called exposures, treatments, actions, policies, or interventions), referred to as \textit{composite treatments}, on a set of outcome…

机器学习 · 计算机科学 2025-12-19 Vinod Kumar Chauhan , Lei Clifton , Gaurav Nigam , David A. Clifton

A/B testing is an important decision-making tool in product development for evaluating user engagement or satisfaction from a new service, feature or product. The goal of A/B testing is to estimate the average treatment effects (ATE) of a…

统计方法学 · 统计学 2020-08-21 Yifan Zhou , Yang Liu , Ping Li , Feifang Hu

Average Treatment Effect (ATE) estimation is a well-studied problem in causal inference. However, it does not necessarily capture the heterogeneity in the data, and several approaches have been proposed to tackle the issue, including…

机器学习 · 计算机科学 2024-03-19 Raghavendra Addanki , Siddharth Bhandari

Randomized controlled trials (RCTs) are the accepted standard for treatment effect estimation but they can be infeasible due to ethical reasons and prohibitive costs. Single-arm trials, where all patients belong to the treatment group, can…

In multi-site randomized trials with many sites and few randomization units per site, an Empirical-Bayes estimator can be used to estimate the variance of the treatment effect across sites. When this estimator indicates that treatment…

计量经济学 · 经济学 2024-12-12 Clément de Chaisemartin , Antoine Deeb

Long-term user behavior sequences are a goldmine for businesses to explore users' interests to improve Click-Through Rate. However, it is very challenging to accurately capture users' long-term interests from their long-term behavior…

信息检索 · 计算机科学 2025-08-20 Wenji Zhou , Yuhang Zheng , Yinfu Feng , Yunan Ye , Rong Xiao , Long Chen , Xiaosong Yang , Jun Xiao

The primary analysis of clinical trials in diabetes therapeutic area often involves a mixed-model repeated measure (MMRM) approach to estimate the average treatment effect for longitudinal continuous outcome, and a generalized linear mixed…

应用统计 · 统计学 2022-08-03 Lingjing Jiang , Michael Rosenblum , Yu Du

Correlated outcomes are common in many practical problems. In some settings, one outcome is of particular interest, and others are auxiliary. To leverage information shared by all the outcomes, traditional multi-task learning (MTL)…

统计方法学 · 统计学 2023-03-23 Muxuan Liang , Jaeyoung Park , Qing Lu , Xiang Zhong

Nowadays, software analytics tools using machine learning (ML) models to, for example, predict the risk of a code change are well established. However, as the goals of a project shift over time, and developers and their habits change, the…

软件工程 · 计算机科学 2024-05-06 Doriane Olewicki , Sarra Habchi , Mathieu Nayrolles , Mojtaba Faramarzi , Sarath Chandar , Bram Adams

Many digital platforms offer advertisers experimentation tools like Meta's Lift and A/B tests to optimize their ad campaigns. Lift tests compare outcomes between users eligible to see ads versus users in a no-ad control group. In contrast,…

综合经济学 · 经济学 2025-09-01 Gordon Burtch , Robert Moakler , Brett R. Gordon , Poppy Zhang , Shawndra Hill

We consider a randomized controlled trial between two groups. The objective is to identify a population with characteristics such that the test therapy is more effective than the control therapy. Such a population is called a subgroup. This…

统计方法学 · 统计学 2021-12-06 Shintaro Yuki , Kensuke Tanioka , Hiroshi Yadohisa

Online controlled experiments (A/B testing) are fundamental to data-driven decision-making in many companies. Improving the sensitivity of these experiments under fixed sample size constraints requires reducing the variance of the average…

统计方法学 · 统计学 2026-03-24 Zhexiao Lin , Pablo Crespo

We study the problem of inferring heterogeneous treatment effects from time-to-event data. While both the related problems of (i) estimating treatment effects for binary or continuous outcomes and (ii) predicting survival outcomes have been…

机器学习 · 计算机科学 2022-01-25 Alicia Curth , Changhee Lee , Mihaela van der Schaar

Identification of heterogeneous treatment effects (HTEs) has been increasingly popular and critical in various penalized strategy decisions using the A/B testing approach, especially in the scenario of a consecutive online collection of…

统计方法学 · 统计学 2024-09-25 Zhiqing Fang , Shuyan Chen , Xin Liu

The aim of clinical effectiveness research using repositories of electronic health records is to identify what health interventions 'work best' in real-world settings. Since there are several reasons why the net benefit of intervention may…

统计方法学 · 统计学 2020-06-19 Jie Zhu , Blanca Gallego

To estimate the dynamic effects of an absorbing treatment, researchers often use two-way fixed effects regressions that include leads and lags of the treatment. We show that in settings with variation in treatment timing across units, the…

计量经济学 · 经济学 2020-09-24 Liyang Sun , Sarah Abraham

Mobile health (mHealth) leverages digital technologies, such as mobile phones, to capture objective, frequent, and real-world digital phenotypes from individuals, enabling the delivery of tailored interventions to accommodate substantial…

统计方法学 · 统计学 2026-03-24 Xingche Guo , Zexi Cai , Yuanjia Wang , Donglin Zeng

Methods for estimating heterogeneous treatment effect in observational data have largely focused on continuous or binary outcomes, and have been relatively less vetted with survival outcomes. Using flexible machine learning methods in the…

应用统计 · 统计学 2021-07-09 Liangyuan Hu , Jiayi Ji , Fan Li

We propose Deep Longitudinal Targeted Minimum Loss-based Estimation (Deep LTMLE), a novel approach to estimate the counterfactual mean of outcome under dynamic treatment policies in longitudinal problem settings. Our approach utilizes a…

机器学习 · 统计学 2025-06-09 Toru Shirakawa , Yi Li , Yulun Wu , Sky Qiu , Yuxuan Li , Mingduo Zhao , Hiroyasu Iso , Mark van der Laan

Combining experimental and observational follow-up datasets has received a lot of attention lately. In a time-to-event setting, recent work has used medicare claims to extend the follow-up period for participants in a prostate cancer…

统计方法学 · 统计学 2022-04-12 Gang Cheng , Yen-Chi Chen , Joseph M. Unger , Cathee Till , Ying-Qi Zhao