相关论文: Multi-Scale Reversible Chaos Game Representation: …

We present a novel information-preserving Chaos Game Representation (CGR) method, also called Reverse-CGR (R-CGR), for biological sequence analysis that addresses the fundamental limitation of traditional CGR approaches - the loss of…

Traditional feature engineering approaches for molecular sequence classification suffer from sparsity issues and computational complexity, while deep learning models often underperform on tabular biological data. This paper introduces a…

DNA sequences are fundamental for encoding genetic information. The genetic information may not only be understood by symbolic sequences but also from the hidden signals inside the sequences. The symbolic sequences need to be transformed…

This paper establishes formal mathematical foundations linking Chaos Game Representations (CGR) of DNA sequences to their underlying $k$-mer frequencies. We prove that the Frequency CGR (FCGR) of order $k$ is mathematically equivalent to a…

Occlusion is a common problem with biometric recognition in the wild. The generalization ability of CNNs greatly decreases due to the adverse effects of various occlusions. To this end, we propose a novel unified framework integrating the…

A new three dimensional approach to the chaos game representation of protein sequences is explored in this thesis. The basics of DNA, the synthesis of proteins from DNA, protein structure and functionality and sequence alignment techniques…

Implicit Neural Representations (INRs) are widely used to encode data as continuous functions, enabling the visualization of large-scale multivariate scientific simulation data with reduced memory usage. However, existing INR-based methods…

Building accurate and interpretable Machine Learning (ML) models for heterogeneous/mixed data is a long-standing challenge for algorithms designed for numeric data. This work focuses on developing numeric coding schemes for non-numeric…

This study proposes CGRclust, a novel combination of unsupervised twin contrastive clustering of Chaos Game Representations (CGR) of DNA sequences, with convolutional neural networks (CNNs). To the best of our knowledge, CGRclust is the…

Accurate molecular sequence analysis is a key task in the field of bioinformatics. To apply molecular sequence classification algorithms, we first need to generate the appropriate representations of the sequences. Traditional numeric…

Masked graph modeling (MGM) is a promising approach for molecular representation learning (MRL).However, extending the success of re-mask decoding from 2D to 3D MGM is non-trivial, primarily due to two conflicting challenges: avoiding 2D…

The analysis of sequences (e.g., protein, DNA, and SMILES string) is essential for disease diagnosis, biomaterial engineering, genetic engineering, and drug discovery domains. Conventional analytical methods focus on transforming sequences…

Cancer is a complex disease characterized by uncontrolled cell growth. T cell receptors (TCRs), crucial proteins in the immune system, play a key role in recognizing antigens, including those associated with cancer. Recent advancements in…

Generative Information Retrieval is an emerging retrieval paradigm that exhibits remarkable performance in monolingual scenarios.However, applying these methods to multilingual retrieval still encounters two primary challenges,…

Multi-hop knowledge graph (KG) reasoning has been widely studied in recent years to provide interpretable predictions on missing links with evidential paths. Most previous works use reinforcement learning (RL) based methods that learn to…

Scene Graph Generation (SGG) structures visual scenes as graphs of objects and their relations. While Multimodal Large Language Models (MLLMs) have advanced end-to-end SGG, current methods are hindered by both a lack of task-specific…

Person re-identification (re-ID) via 3D skeletons is an important emerging topic with many merits. Existing solutions rarely explore valuable body-component relations in skeletal structure or motion, and they typically lack the ability to…

Motivation: With the advent of Language Models using Transformers, popularized by ChatGPT, there is a renewed interest in exploring encoding procedures that numerically represent symbolic sequences at multiple scales and embedding…

Skeleton-based person re-identification (Re-ID) is an emerging open topic providing great value for safety-critical applications. Existing methods typically extract hand-crafted features or model skeleton dynamics from the trajectory of…

Discovering genes with similar functions across diverse biomedical contexts poses a significant challenge in gene representation learning due to data heterogeneity. In this study, we resolve this problem by introducing a novel model called…