中文
相关论文

相关论文: Calibrated Abstention for Reliable TCR--pMHC Bindi…

200 篇论文

Motivation: The activity of the adaptive immune system is governed by T-cells and their specific T-cell receptors (TCR), which selectively recognize foreign antigens. Recent advances in experimental techniques have enabled sequencing of…

生物大分子 · 定量生物学 2023-08-28 Anna Weber , Jannis Born , María Rodríguez Martínez

Code language models are increasingly adopted for both understanding and generative tasks. Despite their success, these models frequently produce overconfident incorrect predictions and underconfident correct predictions, undermining their…

软件工程 · 计算机科学 2026-05-20 Ravishka Rathnasuriya , Wei Yang

We propose a new method for statistical inference in generalized linear models. In the overparameterized regime, Principal Component Regression (PCR) reduces variance by projecting high-dimensional data to a low-dimensional principal…

机器学习 · 统计学 2026-04-27 Yixuan Florence Wu , Yilun Zhu , Lei Cao , Naichen Shi

Hybrid controlled trials (HCTs), which augment randomized controlled trials (RCTs) with external controls (ECs), are increasingly receiving attention as a way to address limited power, slow accrual, and ethical concerns in clinical…

统计方法学 · 统计学 2025-05-02 Jiajun Liu , Ke Zhu , Shu Yang , Xiaofei Wang

Conformal prediction (CP) is a distribution-free framework for achieving probabilistic guarantees on black-box models. CP is generally applied to a model post-training. Recent research efforts, on the other hand, have focused on optimizing…

机器学习 · 计算机科学 2025-02-11 Sima Noorani , Orlando Romero , Nicolo Dal Fabbro , Hamed Hassani , George J. Pappas

The prediction accuracy of machine learning methods is steadily increasing, but the calibration of their uncertainty predictions poses a significant challenge. Numerous works focus on obtaining well-calibrated predictive models, but less is…

机器学习 · 统计学 2023-12-07 Donghwan Lee , Xinmeng Huang , Hamed Hassani , Edgar Dobriban

This paper proposes a novel robust Model Predictive Control (MPC) scheme for linear discrete-time systems affected by model uncertainty described by interval matrices. The key feature of the proposed method is a bound on the uncertainty…

系统与控制 · 电气工程与系统科学 2026-02-20 Renato Quartullo , Andrea Garulli , Mirko Leomanni

In this paper, we present a robust adaptive model predictive control (MPC) scheme for linear systems subject to parametric uncertainty and additive disturbances. The proposed approach provides a computationally efficient formulation with…

系统与控制 · 电气工程与系统科学 2020-03-12 Johannes Köhler , Elisa Andina , Raffaele Soloperto , Matthias A. Müller , Frank Allgöwer

Proper confidence calibration of deep neural networks is essential for reliable predictions in safety-critical tasks. Miscalibration can lead to model over-confidence and/or under-confidence; i.e., the model's confidence in its prediction…

机器学习 · 计算机科学 2023-08-08 Shuang Ao , Stefan Rueger , Advaith Siddharthan

T cells are a critical component of the adaptive immune system, playing a role in infectious disease, autoimmunity, and cancer. T cell function is mediated by the T cell receptor (TCR) protein, a highly diverse receptor targeting specific…

机器学习 · 计算机科学 2026-03-31 Marco Garcia Noceda , Matthew T Noakes , Andrew FigPope , Daniel E Mattox , Bryan Howie , Harlan Robins

Fair calibration is a widely desirable fairness criteria in risk prediction contexts. One way to measure and achieve fair calibration is with multicalibration. Multicalibration constrains calibration error among flexibly-defined…

机器学习 · 计算机科学 2023-09-04 William La Cava , Elle Lett , Guangya Wan

This work introduces a formulation of model predictive control (MPC) which adaptively reasons about the complexity of the model based on the task while maintaining feasibility and stability guarantees. Existing MPC implementations often…

机器人学 · 计算机科学 2024-11-07 Joseph Norby , Ardalan Tajbakhsh , Yanhao Yang , Aaron M. Johnson

Conformal prediction (CP) provides distribution-free, finite-sample coverage guarantees but critically relies on exchangeability, a condition often violated under distribution shift. We study the robustness of split conformal prediction…

机器学习 · 统计学 2025-12-23 Xunlei Qian , Yue Xing

Model calibration aims to align confidence with prediction correctness. The Cross-Entropy (CE) loss is widely used for calibrator training, which enforces the model to increase confidence on the ground truth class. However, we find the CE…

计算机视觉与模式识别 · 计算机科学 2025-02-13 Yuchi Liu , Lei Wang , Yuli Zou , James Zou , Liang Zheng

In binary classification applications, conservative decision-making that allows for abstention can be advantageous. To this end, we introduce a novel approach that determines the optimal cutoff interval for risk scores, which can be…

机器学习 · 统计学 2025-10-01 Yishu Wei , Wen-Yee Lee , George Ekow Quaye , Xiaogang Su

Accurate sensor calibration is crucial for autonomous systems, yet its uncertainty quantification remains underexplored. We present the first approach to integrate uncertainty awareness into online extrinsic calibration, combining Monte…

计算机视觉与模式识别 · 计算机科学 2025-04-28 Mathieu Cocheteux , Julien Moreau , Franck Davoine

We propose a robust adaptive Model Predictive Control (MPC) strategy with online set-based estimation for constrained linear systems with unknown parameters and bounded disturbances. A sample-based test applied to predicted trajectories is…

最优化与控制 · 数学 2023-03-09 Xiaonan Lu , Mark Cannon

Selective classification allows models to abstain from making predictions (e.g., say "I don't know") when in doubt in order to obtain better effective accuracy. While typical selective models can be effective at producing more accurate…

机器学习 · 计算机科学 2024-06-24 Adam Fisch , Tommi Jaakkola , Regina Barzilay

Establishing a secure connection between wireless devices has become significantly important with the increasing number of Wi-Fi products coming to the market. In order to provide an easy and secure pairing standard, the Wi-Fi Alliance has…

密码学与安全 · 计算机科学 2023-11-28 Aleksandar Manev

Minimum Bayes risk (MBR) decoding generates high-quality translations by maximizing the expected utility of output candidates, but it evaluates all pairwise scores over the candidate set; hence, it takes quadratic time with respect to the…

计算与语言 · 计算机科学 2025-12-02 Koki Natsumi , Hiroyuki Deguchi , Yusuke Sakai , Hidetaka Kamigaito , Taro Watanabe