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Traditional disease transmission models assume that the infectious period is exponentially distributed with a recovery rate fixed in time and across individuals. This assumption provides analytical and computational advantages, however it…

种群与进化 · 定量生物学 2024-01-30 Laura Di Domenico , Eugenio Valdano , Vittoria Colizza

We develop a stochastic framework for viral population dynamics at the cellular level that explicitly incorporates the replication cycle with random stage durations. The model is formulated as a structured birth-death process coupled with a…

种群与进化 · 定量生物学 2026-05-13 Seong Jun Park

The duration of the infectious period is a crucial determinant of the ability of an infectious disease to spread. We consider an epidemic model that is network based and non-Markovian, containing classic Kermack-McKendrick, pairwise,…

种群与进化 · 定量生物学 2018-05-25 Robert R. Wilkinson , Kieran J. Sharkey

In the Staged Progression (SP) epidemic models, infected individuals are classified into a suitable number of states. The goal of these models is to describe as closely as possible the effect of differences in infectiousness exhibited by…

动力系统 · 数学 2024-02-08 Luis Sanz-Lorenzo , Rafael Bravo de la Parra

The Markovian approach, which assumes exponentially distributed interinfection times, is dominant in epidemic modeling. However, this assumption is unrealistic as an individual's infectiousness depends on its viral load and varies over…

种群与进化 · 定量生物学 2023-08-02 Qihui Yang , Joan Saldaña , Caterina Scoglio

For a recently derived pairwise model of network epidemics with non-Markovian recovery, we prove that under some mild technical conditions on the distribution of the infectious periods, smaller variance in the recovery time leads to higher…

种群与进化 · 定量生物学 2018-12-27 Zsolt Vizi , István Z. Kiss , Joel C. Miller , Gergely Röst

This paper is concerned with a stochastic model for the spread of an SEIR (susceptible -> exposed (=latent) -> infective -> removed) epidemic with a contact tracing scheme, in which removed individuals may name some of their infectious…

概率论 · 数学 2015-12-08 Frank G Ball , Edward S Knock , Philip D O'Neill

We study an epidemic model for a constant population by taking into account four compartments of the individuals characterizing their states of health. Each individual is in one of the compartments susceptible (S); incubated - infected yet…

种群与进化 · 定量生物学 2023-04-20 Teo Granger , Thomas M. Michelitsch , Michael Bestehorn , Alejandro P. Riascos , Bernard A. Collet

What role do asymptomatically infected individuals play in the transmission dynamics? There are many diseases, such as norovirus and influenza, where some infected hosts show symptoms of the disease while others are asymptomatically…

种群与进化 · 定量生物学 2018-01-29 Ka Yin Leung , Pieter Trapman , Tom Britton

This paper investigates the dynamics of infectious diseases with a non-exponentially distributed infectious period. This is achieved by considering a multi-stage infection model on networks. Using pairwise approximation with a standard…

物理与社会 · 物理学 2015-11-23 N. Sherborne , K. B. Blyuss , I. Z. Kiss

We study a model for the spread of an infectious disease which incorporates spatial and temporal effects. The model is a delayed multi-type branching process in which types represent geographic regions while infected individuals reproduce…

概率论 · 数学 2023-01-27 Andrew Hart , Servet Martínez

In the present work, a non-linear stochastic model is presented to study the effect of time variation of transmission rates on the co-evolution of epidemics and its corresponding awareness over a two layered multiplex network. In this…

物理与社会 · 物理学 2021-12-08 Vikram Sagar , Yi Zhao , Abhijit Sen

Understanding the interplay between human behavioral phenomena and infectious disease dynamics has been one of the central challenges of mathematical epidemiology. However, socio-cognitive processes critical for the initiation of desired…

物理与社会 · 物理学 2024-01-01 Qingchu Wu , Tarik Hadzibeganovic , Xiao-Pu Han

Infectious disease spread is a multi-scale process composed of within-host (biological) and between-host (social) drivers and disentangling them from each other is a central challenge in epidemiology. Here, we introduce VIBES, a multi-scale…

The generation interval is the time between the infection time of an infected person and the infection time of his or her infector. Probability density functions for generation intervals have been an important input for epidemic models and…

定量方法 · 定量生物学 2023-10-24 Eben Kenah , Marc Lipsitch , James M. Robins

In this paper, we consider a compartmental SIRS epidemic model with asymptomatic infection and seasonal succession, which is a periodic discontinuous differential system. The basic reproduction number $\mathcal{R}_0$ is defined and valuated…

动力系统 · 数学 2017-08-15 Yilei Tang , Dongmei Xiao , Weinian Zhang , Di Zhu

Our study is devoted to a four-compartment epidemic model of a constant population of independent random walkers. Each walker is in one of four compartments (S-susceptible, C-infected but not infectious (period of incubation), I-infected…

种群与进化 · 定量生物学 2023-08-29 Teo Granger , Thomas Michelitsch , Bernard Collet , Michael Bestehorn , Alejandro Riascos

Waiting times between two consecutive infection and recovery events in spreading processes are often assumed to be exponentially distributed, which results in Markovian (i.e., memoryless) continuous spreading dynamics. However, this is not…

物理与社会 · 物理学 2020-07-27 Lucas Böttcher , Nino Antulov-Fantulin

Whole genome sequencing of pathogens from multiple hosts in an epidemic offers the potential to investigate who infected whom with unparalleled resolution, potentially yielding important insights into disease dynamics and the impact of…

Epidemic modelling on complex networks has been studied intensively all the time. The majority of relative research assumes that the time scale of the underlying network evolution is much larger compared to the propagation dynamics on it,…

物理与社会 · 物理学 2026-04-14 Minyu Feng , Yuhan Li , Jürgen Kurths
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