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Medical multi-modal pre-training has revealed promise in computer-aided diagnosis by leveraging large-scale unlabeled datasets. However, existing methods based on masked autoencoders mainly rely on data-level reconstruction tasks, but lack…

计算机视觉与模式识别 · 计算机科学 2024-04-10 Yupei Zhang , Li Pan , Qiushi Yang , Tan Li , Zhen Chen

Multimodal Sentiment Analysis (MSA) seeks to understand human emotions by integrating textual, acoustic, and visual signals. Although multimodal fusion is designed to leverage cross-modal complementarity, real-world scenarios often exhibit…

机器学习 · 计算机科学 2025-11-26 Kang He , Boyu Chen , Yuzhe Ding , Fei Li , Chong Teng , Donghong Ji

Deep learning has shown remarkable performance in integrating multimodal data for survival prediction. However, existing multimodal methods mainly focus on single cancer types and overlook the challenge of generalization across cancers. In…

计算机视觉与模式识别 · 计算机科学 2025-09-01 Jia-Xuan Jiang , Jiashuai Liu , Hongtao Wu , Yifeng Wu , Zhong Wang , Qi Bi , Yefeng Zheng

Mask-based pretraining has become a cornerstone of modern large-scale models across language, vision, and recently biology. Despite its empirical success, its role and limits in learning data representations have been unclear. In this work,…

机器学习 · 计算机科学 2025-09-29 Mingze Dong , Leda Wang , Yuval Kluger

An active challenge in developing multimodal machine learning (ML) models for healthcare is handling missing modalities during training and deployment. As clinical datasets are inherently temporal and sparse in terms of modality presence,…

机器学习 · 计算机科学 2026-05-08 Andrew Wang , Ellie Pavlick , Ritambhara Singh

Predicting drug response in patients from preclinical data remains a major challenge in precision oncology due to the substantial biological gap between in vitro cell lines and patient tumors. Rather than aiming to improve absolute in vitro…

机器学习 · 计算机科学 2026-03-18 Camille Jimenez Cortes , Philippe Lalanda , German Vega

Leveraging multimodal information from Magnetic Resonance Imaging (MRI) plays a vital role in lesion segmentation, especially for brain tumors. However, in clinical practice, multimodal MRI data are often incomplete, making it challenging…

计算机视觉与模式识别 · 计算机科学 2026-01-01 Yulong Zou , Bo Liu , Cun-Jing Zheng , Yuan-ming Geng , Siyue Li , Qiankun Zuo , Shuihua Wang , Yudong Zhang , Jin Hong

Multimodal MRI provides critical complementary information for accurate brain tumor segmentation. However, conventional methods struggle when certain modalities are missing due to issues such as image quality, protocol inconsistencies,…

计算机视觉与模式识别 · 计算机科学 2025-07-03 Runze Cheng , Xihang Qiu , Ming Li , Ye Zhang , Chun Li , Fei Yu

Cancer prognosis and survival outcome predictions are crucial for therapeutic response estimation and for stratifying patients into various treatment groups. Medical domains concerned with cancer prognosis are abundant with multiple…

图像与视频处理 · 电气工程与系统科学 2024-02-29 Ruining Deng , Nazim Shaikh , Gareth Shannon , Yao Nie

Real-life medical data is often multimodal and incomplete, fueling the growing need for advanced deep learning models capable of integrating them efficiently. The use of diverse modalities, including histopathology slides, MRI, and genetic…

人工智能 · 计算机科学 2024-10-02 Lucas Robinet , Ahmad Berjaoui , Ziad Kheil , Elizabeth Cohen-Jonathan Moyal

The scarcity of high-quality multimodal biomedical data limits the ability to effectively fine-tune pretrained Large Language Models (LLMs) for specialized biomedical tasks. To address this challenge, we introduce MINT (Multimodal…

定量方法 · 定量生物学 2026-02-18 Zhanliang Wang , Da Wu , Quan Nguyen , Zhuoran Xu , Kai Wang

Self-supervised pretraining has been extensively studied in language and vision domains, where a unified model can be easily adapted to various downstream tasks by pretraining representations without explicit labels. When it comes to…

机器学习 · 计算机科学 2023-01-25 Yanchao Sun , Shuang Ma , Ratnesh Madaan , Rogerio Bonatti , Furong Huang , Ashish Kapoor

Multimodal learning, integrating histology images and genomics, promises to enhance precision oncology with comprehensive views at microscopic and molecular levels. However, existing methods may not sufficiently model the shared or…

计算机视觉与模式识别 · 计算机科学 2024-06-12 Huahui Yi , Xiaofei Wang , Kang Li , Chao Li

Multimodal pretraining is effective for building general-purpose representations, but in many practical deployments, only one modality is heavily used during downstream fine-tuning. Standard pretraining strategies treat all modalities…

机器学习 · 计算机科学 2026-01-30 Atik Faysal , Mohammad Rostami , Reihaneh Gh. Roshan , Nikhil Muralidhar , Huaxia Wang

Multimodal Magnetic Resonance Imaging (MRI) provides essential complementary information for analyzing brain tumor subregions. While methods using four common MRI modalities for automatic segmentation have shown success, they often face…

图像与视频处理 · 电气工程与系统科学 2024-11-14 Runze Cheng , Zhongao Sun , Ye Zhang , Chun Li

Missing or corrupted modalities are common in physiological signal-based medical applications owing to hardware constraints or motion artifacts. However, most existing methods assume the availability of all modalities, resulting in…

机器学习 · 计算机科学 2025-10-14 Cheol-Hui Lee , Hwa-Yeon Lee , Min-Kyung Jung , Dong-Joo Kim

Prompt tuning has become a new paradigm for model tuning and it has demonstrated success in natural language pretraining and even vision pretraining. In this work, we explore the transfer of prompt tuning to multimodal pretraining, with a…

计算与语言 · 计算机科学 2022-08-05 Hao Yang , Junyang Lin , An Yang , Peng Wang , Chang Zhou , Hongxia Yang

Multimodal deep learning (MDL) has emerged as a transformative approach in computational pathology. By integrating complementary information from multiple data sources, MDL models have demonstrated superior predictive performance across…

定量方法 · 定量生物学 2025-11-17 Seth Alain Chang , Muhammad Mueez Amjad , Noorul Wahab , Ethar Alzaid , Nasir Rajpoot , Adam Shephard

Prompt learning has emerged as an efficient alternative for fine-tuning foundational models, such as CLIP, for various downstream tasks. However, there is no work that provides a comprehensive explanation for the working mechanism of the…

计算机视觉与模式识别 · 计算机科学 2024-03-13 Shuailei Ma , Chen-Wei Xie , Ying Wei , Siyang Sun , Jiaqi Fan , Xiaoyi Bao , Yuxin Guo , Yun Zheng

Healthcare applications are inherently multimodal, benefiting greatly from the integration of diverse data sources. However, the modalities available in clinical settings can vary across different locations and patients. A key area that…

计算机视觉与模式识别 · 计算机科学 2025-09-04 Mohammed Amer , Mohamed A. Suliman , Tu Bui , Nuria Garcia , Serban Georgescu