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Current multimodal fusion approaches in computational oncology primarily focus on integrating multi-gigapixel histology whole slide images (WSIs) with genomic or transcriptomic data, demonstrating improved survival prediction. We…

计算机视觉与模式识别 · 计算机科学 2025-09-25 Manahil Raza , Ayesha Azam , Talha Qaiser , Nasir Rajpoot

Self-supervised learning, a.k.a., pretraining, is important in natural language processing. Most of the pretraining methods first randomly mask some positions in a sentence and then train a model to recover the tokens at the masked…

计算与语言 · 计算机科学 2020-08-18 Liang Chen

Multimodal Machine Learning offers a holistic view of a patient's status, integrating structured and unstructured data from electronic health records (EHR). We propose a framework to predict metastasis risk one month prior to diagnosis,…

机器学习 · 计算机科学 2026-04-01 Franco Rugolon , Korbinian Randl , Braslav Jovanovic , Ioanna Miliou , Panagiotis Papapetrou

Multi-modality pre-training paradigm that aligns protein sequences and biological descriptions has learned general protein representations and achieved promising performance in various downstream applications. However, these works were…

机器学习 · 计算机科学 2024-12-31 Hanjing Zhou , Mingze Yin , Wei Wu , Mingyang Li , Kun Fu , Jintai Chen , Jian Wu , Zheng Wang

Foundation models have recently achieved impressive success in computational pathology, demonstrating strong generalization across diverse histopathology tasks. However, existing models overlook the heterogeneous and non-uniform…

Various multi-instance learning (MIL) based approaches have been developed and successfully applied to whole-slide pathological images (WSI). Existing MIL methods emphasize the importance of feature aggregators, but largely neglect the…

计算机视觉与模式识别 · 计算机科学 2025-05-13 Yicheng Song , Tiancheng Lin , Die Peng , Su Yang , Yi Xu

Semi-supervised learning (SSL) has become a promising direction for medical image segmentation, enabling models to learn from limited labeled data alongside abundant unlabeled samples. However, existing SSL approaches for multi-modal…

计算机视觉与模式识别 · 计算机科学 2025-12-11 Tien-Dat Chung , Ba-Thinh Lam , Thanh-Huy Nguyen , Thien Nguyen , Nguyen Lan Vi Vu , Hoang-Loc Cao , Phat Kim Huynh , Min Xu

In this study, we present a multimodal framework for predicting neuro-facial disorders by capturing both vocal and facial cues. We hypothesize that explicitly disentangling shared and modality-specific representations within multimodal…

音频与语音处理 · 电气工程与系统科学 2026-01-13 Mohd Mujtaba Akhtar , Girish , Muskaan Singh

The Contrastive Language-Image Pre-training (CLIP) framework has become a widely used approach for multimodal representation learning, particularly in image-text retrieval and clustering. However, its efficacy is constrained by three key…

计算机视觉与模式识别 · 计算机科学 2025-12-09 Tiancheng Gu , Kaicheng Yang , Ziyong Feng , Xingjun Wang , Yanzhao Zhang , Dingkun Long , Yingda Chen , Weidong Cai , Jiankang Deng

To improve the prediction of cancer survival using whole-slide images and transcriptomics data, it is crucial to capture both modality-shared and modality-specific information. However, multimodal frameworks often entangle these…

计算机视觉与模式识别 · 计算机科学 2025-06-30 Aniek Eijpe , Soufyan Lakbir , Melis Erdal Cesur , Sara P. Oliveira , Sanne Abeln , Wilson Silva

Medical multimodal learning faces significant challenges with missing modalities prevalent in clinical practice. Existing approaches assume equal contribution of modality and random missing patterns, neglecting inherent uncertainty in…

机器学习 · 计算机科学 2026-01-30 Linxiao Gong , Yang Liu , Lianlong Sun , Yulai Bi , Jing Liu , Xiaoguang Zhu

An accurate binding affinity prediction between T-cell receptors and epitopes contributes decisively to develop successful immunotherapy strategies. Some state-of-the-art computational methods implement deep learning techniques by…

机器学习 · 计算机科学 2024-01-18 Etienne Goffinet , Raghvendra Mall , Ankita Singh , Rahul Kaushik , Filippo Castiglione

Breast Magnetic Resonance Imaging (MRI) demonstrates the highest sensitivity for breast cancer detection among imaging modalities and is standard practice for high-risk women. Interpreting the multi-sequence MRI is time-consuming and prone…

计算机视觉与模式识别 · 计算机科学 2025-04-08 Luyang Luo , Mingxiang Wu , Mei Li , Yi Xin , Qiong Wang , Varut Vardhanabhuti , Winnie CW Chu , Zhenhui Li , Juan Zhou , Pranav Rajpurkar , Hao Chen

Recent neuroimaging studies that focus on predicting brain disorders via modern machine learning approaches commonly include a single modality and rely on supervised over-parameterized models.However, a single modality provides only a…

Multi-modal image registration plays a critical role in precision medicine but faces challenges from non-linear intensity relationships and local optima. While deep learning models enable rapid inference, they often suffer from…

图像与视频处理 · 电气工程与系统科学 2026-04-14 Boya Wang , Ruizhe Li , Chao Chen , Xin Chen

Existing self-supervised learning strategies are constrained to either a limited set of objectives or generic downstream tasks that predominantly target uni-modal applications. This has isolated progress for imperative multi-modal…

计算与语言 · 计算机科学 2022-09-30 Shivam Sharma , Mohd Khizir Siddiqui , Md. Shad Akhtar , Tanmoy Chakraborty

Multimodal semantic communication has gained widespread attention due to its ability to enhance downstream task performance. A key challenge in such systems is the effective fusion of features from different modalities, which requires the…

图像与视频处理 · 电气工程与系统科学 2025-09-03 Haoshuo Zhang , Yufei Bo , Hongwei Zhang , Meixia Tao

Accurate classification of medical device risk levels is essential for regulatory oversight and clinical safety. We present a Transformer-based multimodal framework that integrates textual descriptions and visual information to predict…

机器学习 · 计算机科学 2025-05-02 Yu Han , Aaron Ceross , Jeroen H. M. Bergmann

Large-scale pre-training has brought unimodal fields such as computer vision and natural language processing to a new era. Following this trend, the size of multi-modal learning models constantly increases, leading to an urgent need to…

计算机视觉与模式识别 · 计算机科学 2023-05-16 Yaowei Li , Ruijie Quan , Linchao Zhu , Yi Yang

The rapidly emerging field of deep learning-based computational pathology has demonstrated promise in developing objective prognostic models from histology whole slide images. However, most prognostic models are either based on histology or…

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