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In science and social science, we often wish to explain why an outcome is different in two populations. For instance, if a jobs program benefits members of one city more than another, is that due to differences in program participants…

统计方法学 · 统计学 2025-04-24 Manuel Quintero , William T. Stephenson , Advik Shreekumar , Tamara Broderick

The Kitagawa-Oaxaca-Blinder decomposition splits the difference in means between two groups into an explained part, due to observable factors, and an unexplained part. In this paper, we reformulate this framework using potential outcomes,…

计量经济学 · 经济学 2025-11-18 Emmanuel Flachaire , Bertille Picard

There has been considerable interest in using decomposition methods in epidemiology (mediation analysis) and economics (Oaxaca-Blinder decomposition) to understand how health disparities arise and how they might change upon intervention. It…

统计方法学 · 统计学 2017-03-20 John W. Jackson , Tyler J. VanderWeele

We introduce a new nonparametric causal decomposition approach that identifies the mechanisms by which a treatment variable contributes to a group-based outcome disparity. Our approach distinguishes three mechanisms: group differences in 1)…

统计方法学 · 统计学 2024-12-17 Ang Yu , Felix Elwert

When deploying machine learning models in high-stakes real-world environments such as health care, it is crucial to accurately assess the uncertainty concerning a model's prediction on abnormal inputs. However, there is a scarcity of…

机器学习 · 计算机科学 2020-11-20 Dennis Ulmer , Lotta Meijerink , Giovanni Cinà

We establish, from the point of view of Explainable AI (XAI), connections between Consistency-Based Diagnosis (CBD), on one side, and Actual Causality and Causal Responsibility, on the other. CBD has received little attention from the XAI…

人工智能 · 计算机科学 2026-05-12 Leopoldo Bertossi

Outcome-dependent sampling designs are common in many different scientific fields including epidemiology, ecology, and economics. As with all observational studies, such designs often suffer from unmeasured confounding, which generally…

统计方法学 · 统计学 2020-10-13 Erin E. Gabriel , Michael C. Sachs , Arvid Sjölander

The difference-in-differences (DID) design is widely used in observational studies to estimate the causal effect of a treatment when repeated observations over time are available. Yet, almost all existing methods assume linearity in the…

应用统计 · 统计学 2020-09-29 Soichiro Yamauchi

Background: This study investigates how variations in Major Depressive Disorder (MDD) symptoms, quantified by the Hamilton Rating Scale for Depression (HAM-D), causally influence the prescription of SSRIs versus SNRIs. Methods: We applied…

Difference-in-differences is undoubtedly one of the most widely used methods for evaluating the causal effect of an intervention in observational (i.e., nonrandomized) settings. The approach is typically used when pre- and post-exposure…

统计方法学 · 统计学 2023-08-21 Eric Tchetgen Tchetgen , Chan Park , David Richardson

Recommender systems use users' historical interactions to learn their preferences and deliver personalized recommendations from a vast array of candidate items. Current recommender systems primarily rely on the assumption that the training…

信息检索 · 计算机科学 2024-04-24 Zhuhang Li , Ning Yang

For obtaining causal inferences that are objective, and therefore have the best chance of revealing scientific truths, carefully designed and executed randomized experiments are generally considered to be the gold standard. Observational…

应用统计 · 统计学 2008-11-12 Donald B. Rubin

Consider a general setting in which data on an outcome is collected in two `groups' at two time periods, with certain group-periods deemed `treated' and others `untreated'. A special case is the canonical Difference-in-Differences (DiD)…

统计方法学 · 统计学 2025-09-15 Zach Shahn , Laura Hatfield

Subgroup-specific meta-analysis synthesizes treatment effects for patient subgroups across randomized trials. Methods include joint or separate modeling of subgroup effects and treatment-by-subgroup interactions, but inconsistencies arise…

统计方法学 · 统计学 2025-08-22 Renato Panaro , Christian Röver , Tim Friede

Estimating the causal effect of a treatment or health policy with observational data can be challenging due to an imbalance of and a lack of overlap between treated and control covariate distributions. In the presence of limited overlap,…

统计方法学 · 统计学 2025-03-24 Martha Barnard , Jared D. Huling , Julian Wolfson

In modern drug development, the broader availability of high-dimensional observational data provides opportunities for scientist to explore subgroup heterogeneity, especially when randomized clinical trials are unavailable due to cost and…

统计方法学 · 统计学 2021-02-24 Xinzhou Guo , Linqing Wei , Chong Wu , Jingshen Wang

Multivariate meta-analysis (MMA) is a powerful tool for jointly estimating multiple outcomes' treatment effects. However, the validity of results from MMA is potentially compromised by outcome reporting bias (ORB), or the tendency for…

应用统计 · 统计学 2021-10-19 Ray Bai , Xiaokang Liu , Lifeng Lin , Yulun Liu , Stephen E. Kimmel , Haitao Chu , Yong Chen

Outcome Reporting Bias (ORB) poses significant threats to the validity of meta-analytic findings. It occurs when researchers selectively report outcomes based on the significance or direction of results, potentially leading to distorted…

统计方法学 · 统计学 2025-07-17 Alessandra Gaia Saracini , Leonhard Held

A common practice in evidence-based decision-making uses estimates of conditional probabilities P(y|x) obtained from research studies to predict outcomes y on the basis of observed covariates x. Given this information, decisions are then…

计量经济学 · 经济学 2025-12-08 Atheendar S. Venkataramani , Charles F. Manski , John Mullahy

This paper introduces a novel decomposition framework to explain heterogeneity in causal effects observed across different studies, considering both observational and randomized settings. We present a formal decomposition of between-study…

统计方法学 · 统计学 2025-12-18 Brian Gilbert , Ivan Dıaz , Kara E. Rudolph , Nicholas Williams , Tat-Thang Vo
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