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Single-cell RNA sequencing (scRNA-seq) has revolutionized our ability to analyze gene expression at the cellular level. By providing data on gene expression for each individual cell, scRNA-seq generates large datasets with thousands of…

计算复杂性 · 计算机科学 2025-02-11 Md Romizul Islam , Swakkhar Shatabda

Remote sensing pansharpening aims to reconstruct spatial-spectral properties during the fusion of panchromatic (PAN) images and low-resolution multi-spectral (LR-MS) images, finally generating the high-resolution multi-spectral (HR-MS)…

计算机视觉与模式识别 · 计算机科学 2025-02-10 Mengting Ma , Yizhen Jiang , Mengjiao Zhao , Jiaxin Li , Wei Zhang

High-dimensional single-cell data poses significant challenges in identifying underlying biological patterns due to the complexity and heterogeneity of cellular states. We propose a comprehensive gene-cell dependency visualization via…

机器学习 · 计算机科学 2024-07-25 Shang-Jung Wen , Jia-Ming Chang , Fang Yu

We introduce a novel ensemble approach for feature selection based on hierarchical stacking for non-stationarity and/or a limited number of samples with a large number of features. Our approach exploits the co-dependency between features…

机器学习 · 计算机科学 2024-10-08 Aysin Tumay , Mustafa E. Aydin , Ali T. Koc , Suleyman S. Kozat

Network embedding (NE) approaches have emerged as a predominant technique to represent complex networks and have benefited numerous tasks. However, most NE approaches rely on a homophily assumption to learn embeddings with the guidance of…

社会与信息网络 · 计算机科学 2022-12-23 Zhiqiang Zhong , Guadalupe Gonzalez , Daniele Grattarola , Jun Pang

Single-cell RNA sequencing (scRNA-seq) technologies have enabled the profiling of gene expression for a collection of cells across time during a dynamic biological process. Given that each time point provides only a static snapshot,…

应用统计 · 统计学 2025-06-16 Binghao Yan , Hongzhe Li

Recently various types of topological Laplacians have been studied from the perspective of data analysis. The spectral theory of these Laplacians has significantly extended the scope of algebraic topology and data analysis. Inspired by the…

代数拓扑 · 数学 2023-12-06 Xiaoqi Wei , Guo-Wei Wei

The swift advancement of single-cell RNA sequencing (scRNA-seq) technologies enables the investigation of cellular-level tissue heterogeneity. Cell annotation significantly contributes to the extensive downstream analysis of scRNA-seq data.…

机器学习 · 计算机科学 2024-11-28 Huifa Li , Jie Fu , Xinpeng Ling , Zhiyu Sun , Kuncan Wang , Zhili Chen

Heterogeneous information network (HIN) embedding has recently attracted much attention due to its effectiveness in dealing with the complex heterogeneous data. Meta path, which connects different object types with various semantic…

社会与信息网络 · 计算机科学 2019-05-15 Sheng Zhou , Jiajun Bu , Xin Wang , Jiawei Chen , Can Wang

Single-cell transcriptomics enabled the study of cellular heterogeneity in response to perturbations at the resolution of individual cells. However, scaling high-throughput screens (HTSs) to measure cellular responses for many drugs remains…

机器学习 · 计算机科学 2023-01-03 Leon Hetzel , Simon Böhm , Niki Kilbertus , Stephan Günnemann , Mohammad Lotfollahi , Fabian Theis

Single-cell RNA sequencing (scRNA-seq) is a relatively new technology that has stimulated enormous interest in statistics, data science, and computational biology due to the high dimensionality, complexity, and large scale associated with…

机器学习 · 统计学 2023-10-25 Yuta Hozumi , Guo-Wei Wei

A recently developed upscaling technique, the multicontinuum homogenization method, has gained significant attention for its effectiveness in modeling complex multiscale systems. This method defines multiple continua based on distinct…

数值分析 · 数学 2025-12-24 Wei Xie , Viet Ha Hoang , Yin Yang , Yunqing Huang

Incorporating heterogeneous representations from different architectures has facilitated various vision tasks, e.g., some hybrid networks combine transformers and convolutions. However, complementarity between such heterogeneous…

计算机视觉与模式识别 · 计算机科学 2025-10-15 Zhong-Yu Li , Bo-Wen Yin , Yongxiang Liu , Li Liu , Ming-Ming Cheng

Graphs with heterophily, where adjacent nodes carry different labels, are prevalent in real-world applications, from social networks to molecular interactions. However, existing spectral Graph Neural Network (GNN) approaches tailored for…

机器学习 · 计算机科学 2026-05-13 Md Sazzad Hossen , Avimanyu Sahoo

Spectral clustering is a key research topic in the field of machine learning and data mining. Most of the existing spectral clustering algorithms are built upon Gaussian Laplacian matrices, which are sensitive to parameters. We propose a…

机器学习 · 计算机科学 2015-10-07 Xiaojun Chang , Feiping Nie , Yi Yang , Heng Huang

The joint optimization of representation learning and clustering in the embedding space has experienced a breakthrough in recent years. In spite of the advance, clustering with representation learning has been limited to flat-level…

机器学习 · 计算机科学 2019-03-26 Su-Jin Shin , Kyungwoo Song , Il-Chul Moon

Inference in deep neural networks can be computationally expensive, and networks capable of anytime inference are important in mscenarios where the amount of compute or quantity of input data varies over time. In such networks the inference…

计算机视觉与模式识别 · 计算机科学 2020-12-15 Adria Ruiz , Jakob Verbeek

Cell type identification from single-cell transcriptomic data is a common goal of single-cell RNA sequencing (scRNAseq) data analysis. Neural networks have been employed to identify cell types from scRNAseq data with high performance.…

基因组学 · 定量生物学 2020-05-11 Xishuang Dong , Shanta Chowdhury , Uboho Victor , Xiangfang Li , Lijun Qian

In this paper, a hierarchical attention network to generate utterance-level embeddings (H-vectors) for speaker identification is proposed. Since different parts of an utterance may have different contributions to speaker identities, the use…

计算与语言 · 计算机科学 2019-10-22 Yanpei Shi , Qiang Huang , Thomas Hain

Combinatorial and topological structures, such as graphs, simplicial complexes, and cell complexes, form the foundation of geometric and topological deep learning (GDL and TDL) architectures. These models aggregate signals over such…

机器学习 · 计算机科学 2026-05-28 Chuan-Shen Hu