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Age-related macular degeneration (AMD) is the most common cause of blindness in developed countries, especially in people over 60 years of age. The workload of specialists and the healthcare system in this field has increased in recent…

图像与视频处理 · 电气工程与系统科学 2022-02-07 Saman Sotoudeh-Paima , Ata Jodeiri , Fedra Hajizadeh , Hamid Soltanian-Zadeh

Handheld Optical Coherence Tomography Angiography (OCTA) enables noninvasive retinal imaging in uncooperative or pediatric subjects, but is highly susceptible to motion artifacts that severely degrade volumetric image quality. Sudden motion…

计算机视觉与模式识别 · 计算机科学 2026-02-03 Nick DiSanto , Ehsan Khodapanah Aghdam , Han Liu , Jacob Watson , Yuankai K. Tao , Hao Li , Ipek Oguz

Segmentation of blood vessels in murine cerebral 3D OCTA images is foundational for in vivo quantitative analysis of the effects of neurovascular disorders, such as stroke or Alzheimer's, on the vascular network. However, to accurately…

图像与视频处理 · 电气工程与系统科学 2024-03-13 Bastian Wittmann , Lukas Glandorf , Johannes C. Paetzold , Tamaz Amiranashvili , Thomas Wälchli , Daniel Razansky , Bjoern Menze

Age-related macular degeneration (AMD) is a degenerative disorder affecting the macula, a key area of the retina for visual acuity. Nowadays, it is the most frequent cause of blindness in developed countries. Although some promising…

图像与视频处理 · 电气工程与系统科学 2022-12-06 José Morano , Álvaro S. Hervella , José Rouco , Jorge Novo , José I. Fernández-Vigo , Marcos Ortega

Machine Learning (ML) is used to tackle various tasks, such as disease classification and prediction. The effectiveness of ML models relies heavily on having large amounts of complete data. However, healthcare data is often limited or…

Existing methods to reconstruct vascular structures from a computed tomography (CT) angiogram rely on injection of intravenous contrast to enhance the radio-density within the vessel lumen. However, pathological changes can be present in…

图像与视频处理 · 电气工程与系统科学 2020-02-11 Anirudh Chandrashekar , Ashok Handa , Natesh Shivakumar , Pierfrancesco Lapolla , Vicente Grau , Regent Lee

In recent years, there has been significant development in the analysis of medical data using machine learning. It is believed that the onset of Age-related Macular Degeneration (AMD) is associated with genetic polymorphisms. However,…

计算机视觉与模式识别 · 计算机科学 2024-09-18 Yoichi Furukawa , Satoshi Kamiya , Yoichi Sakurada , Kenji Kashiwagi , Kazuhiro Hotta

In ophthalmology, intravitreal operative medication therapy (IVOM) is a widespread treatment for diseases related to the age-related macular degeneration (AMD), the diabetic macular edema (DME), as well as the retinal vein occlusion (RVO).…

图像与视频处理 · 电气工程与系统科学 2024-10-03 Tobias Schlosser , Frederik Beuth , Trixy Meyer , Arunodhayan Sampath Kumar , Gabriel Stolze , Olga Furashova , Katrin Engelmann , Danny Kowerko

Retinal vessel segmentation plays a vital role in analyzing fundus images for the diagnosis of systemic and ocular diseases. Building on this, classifying segmented vessels into arteries and veins (A/V) further enables the extraction of…

图像与视频处理 · 电气工程与系统科学 2025-08-07 Shuang Zeng , Chee Hong Lee , Kaiwen Li , Boxu Xie , Ourui Fu , Hangzhou He , Lei Zhu , Yanye Lu , Fangxiao Cheng

Optical coherence tomography (OCT) helps ophthalmologists assess macular edema, accumulation of fluids, and lesions at microscopic resolution. Quantification of retinal fluids is necessary for OCT-guided treatment management, which relies…

图像与视频处理 · 电气工程与系统科学 2022-12-15 Reza Rasti , Armin Biglari , Mohammad Rezapourian , Ziyun Yang , Sina Farsiu

In light of the expanding population, an automated framework of disease detection can assist doctors in the diagnosis of ocular diseases, yields accurate, stable, rapid outcomes, and improves the success rate of early detection. The work…

图像与视频处理 · 电气工程与系统科学 2023-08-31 Md. Aiyub Ali , Md. Shakhawat Hossain , Md. Kawar Hossain , Subhadra Soumi Sikder , Sharun Akter Khushbu , Mirajul Islam

Age-related macular degeneration (AMD) and choroidal neovascularization (CNV)-related conditions are leading causes of vision loss worldwide, with optical coherence tomography (OCT) serving as a cornerstone for early detection and…

计算机视觉与模式识别 · 计算机科学 2026-02-26 Erfan Nourbakhsh , Nasrin Sanjari , Ali Nourbakhsh

Optical Coherence Tomography Angiography (OCTA) is a promising tool for detecting Alzheimer's disease (AD) by imaging the retinal microvasculature. Ophthalmologists commonly use region-based analysis, such as the ETDRS grid, to study OCTA…

图像与视频处理 · 电气工程与系统科学 2023-11-13 Shouyue Liu , Jinkui Hao , Yanwu Xu , Huazhu Fu , Xinyu Guo , Jiang Liu , Yalin Zheng , Yonghuai Liu , Jiong Zhang , Yitian Zhao

Optical coherence tomography angiography (OCTA) performs non-invasive visualization and characterization of microvasculature in research and clinical applications mainly in ophthalmology and dermatology. A wide variety of instruments,…

Segmenting of clinically important retinal blood vessels into arteries and veins is a prerequisite for retinal vessel analysis. Such analysis can provide potential insights and bio-markers for identifying and diagnosing various retinal eye…

计算机视觉与模式识别 · 计算机科学 2025-10-07 Sharan SK , Subin Sahayam , Umarani Jayaraman , Lakshmi Priya A

The measurement of retinal blood flow (RBF) in capillaries can provide a powerful biomarker for the early diagnosis and treatment of ocular diseases. However, no single modality can determine capillary flowrates with high precision.…

图像与视频处理 · 电气工程与系统科学 2024-07-16 Chiao-Yi Wang , Faranguisse Kakhi Sadrieh , Yi-Ting Shen , Shih-En Chen , Sarah Kim , Victoria Chen , Achyut Raghavendra , Dongyi Wang , Osamah Saeedi , Yang Tao

Optical coherence tomography (OCT) based measurements of retinal layer thickness, such as the retinal nerve fibre layer (RNFL) and the ganglion cell with inner plexiform layer (GCIPL) are commonly used for the diagnosis and monitoring of…

计算机视觉与模式识别 · 计算机科学 2019-10-25 Stefan Maetschke , Bhavna Antony , Hiroshi Ishikawa , Gadi Wollstein , Joel S. Schuman , Rahil Garnavi

Age-related macular degeneration (AMD) is the leading cause of visual impairment among elderly in the world. Early detection of AMD is of great importance, as the vision loss caused by this disease is irreversible and permanent. Color…

Cardiovascular disease (CVD) remains the leading cause of death worldwide, requiring urgent development of effective risk assessment methods for timely intervention. While current research has introduced non-invasive and efficient…

计算机视觉与模式识别 · 计算机科学 2025-07-29 Lehan Wang , Hualiang Wang , Chubin Ou , Lushi Chen , Yunyi Liang , Xiaomeng Li

Automatic quantification of perifoveal vessel densities in optical coherence tomography angiography (OCT-A) images face challenges such as variable intra- and inter-image signal to noise ratios, projection artefacts from outer vasculature…