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We aim to enhance ophthalmologists' decision-making when diagnosing the Neovascular Age-Related Macular Degeneration (nAMD). We developed three tools to analyze Optical Coherence Tomography Angiography images: (1) extracting biomarkers such…

图像与视频处理 · 电气工程与系统科学 2026-01-28 MAria Simona Tivadar , Ioana Damian , Adrian Groza , Simona Delia Nicoara

Optical coherence tomography angiography (OCTA) is a non-invasive imaging technique widely used to study vascular structures and micro-circulation dynamics in the retina and choroid. OCTA has been widely used in clinics for diagnosing…

图像与视频处理 · 电气工程与系统科学 2025-08-26 Kejie Chen , Guanbing Gao , Xiaochun Yang , Wenbo Wang , Jing Na

Eye diseases are common in older Americans and can lead to decreased vision and blindness. Recent advancements in imaging technologies allow clinicians to capture high-quality images of the retinal blood vessels via Optical Coherence…

计算机视觉与模式识别 · 计算机科学 2024-07-23 Jacob Thrasher , Annahita Amireskandari , Prashnna Gyawali

Optical coherence tomography angiography (OCTA) is a non-invasive imaging modality that extends the functionality of OCT by extracting moving red blood cell signals from surrounding static biological tissues. OCTA has emerged as a valuable…

图像与视频处理 · 电气工程与系统科学 2023-05-04 Jinpeng Liao , Tianyu Zhang , Yilong Zhang , Chunhui Li , Zhihong Huang

Diseases are currently managed by grading systems, where patients are stratified by grading systems into stages that indicate patient risk and guide clinical management. However, these broad categories typically lack prognostic value, and…

Age-related Macular Degeneration (AMD) and Diabetic Macular Edema (DME) are the major causes of vision loss in developed countries. Alteration of retinal layer structure and appearance of exudate are the most significant signs of these…

图像与视频处理 · 电气工程与系统科学 2019-03-19 Elahe Mousavi , Rahele Kafieh , Hossein Rabbani

Optical Coherence Tomography Angiography (OCTA) is a crucial imaging technique for visualizing retinal vasculature and diagnosing eye diseases such as diabetic retinopathy and glaucoma. However, precise segmentation of OCTA vasculature…

图像与视频处理 · 电气工程与系统科学 2025-01-03 Shun Zou , Zhuo Zhang , Guangwei Gao

Optical Coherence Tomography Angiography (OCTA) is a non-invasive imaging technique that provides high-resolution cross-sectional images of the retina, which are useful for diagnosing and monitoring various retinal diseases. However, manual…

图像与视频处理 · 电气工程与系统科学 2023-11-07 Can Koz , Onat Dalmaz , Mertay Dayanc

Despite significant advances in artificial intelligence (AI) for computer vision, its application in medical imaging has been limited by the burden and limits of expert-generated labels. We used images from optical coherence tomography…

计算机视觉与模式识别 · 计算机科学 2018-02-27 Cecilia S. Lee , Ariel J. Tyring , Yue Wu , Sa Xiao , Ariel S. Rokem , Nicolaas P. Deruyter , Qinqin Zhang , Adnan Tufail , Ruikang K. Wang , Aaron Y. Lee

Optical Coherence Tomography (OCT) provides a unique ability to image the eye retina in 3D at micrometer resolution and gives ophthalmologist the ability to visualize retinal diseases such as Age-Related Macular Degeneration (AMD). While…

计算机视觉与模式识别 · 计算机科学 2016-10-13 Stefanos Apostolopoulos , Carlos Ciller , Sandro I. De Zanet , Sebastian Wolf , Raphael Sznitman

Optical coherence tomography angiography (OCTA) has drawn numerous attentions in ophthalmology. However, its data acquisition is time-consuming, because it is based on temporal-decorrelation principle thus requires multiple repeated…

医学物理 · 物理学 2019-10-15 Jianlong Yang , Peng Liu , Lixin Duan , Yan Hu , Jiang Liu

Recent studies suggest that early stages of diabetic retinopathy (DR) can be diagnosed by monitoring vascular changes in the deep vascular complex. In this work, we investigate a novel method for automated DR grading based on optical…

图像与视频处理 · 电气工程与系统科学 2022-12-22 Linus Kreitner , Ivan Ezhov , Daniel Rueckert , Johannes C. Paetzold , Martin J. Menten

Geographic atrophy (GA) is a key biomarker of dry age-related macular degeneration (AMD) traditionally identified through color fundus photography. Hyper-transmission defects (hyperTDs), a feature highly correlated with GA, have recently…

定量方法 · 定量生物学 2025-11-04 Yukun Guo , An-Lun Wu , Tristan T. Hormel , Liqin Gao , Min Gao , Thomas S. Hwang , Steven T. Bailey , Yali Jia

We propose a method to predict severity of age related macular degeneration (AMD) from input optical coherence tomography (OCT) images. Although there is no standard clinical severity scale for AMD, we leverage deep learning (DL) based…

计算机视觉与模式识别 · 计算机科学 2019-07-09 Dwarikanath Mahapatra

Optical coherence tomography angiography (OCTA) is a novel noninvasive imaging modality for visualization of retinal blood flow in the human retina. Using specific OCTA imaging biomarkers for the identification of pathologies, automated…

图像与视频处理 · 电气工程与系统科学 2025-04-09 Anna Breger , Felix Goldbach , Bianca S. Gerendas , Ursula Schmidt-Erfurth , Martin Ehler

Age-related Macular Degeneration (AMD) is a leading cause of blindness. Although the Age-Related Eye Disease Study group previously developed a 9-step AMD severity scale for manual classification of AMD severity from color fundus images,…

机器学习 · 计算机科学 2018-12-04 Qingyu Chen , Yifan Peng , Tiarnan Keenan , Shazia Dharssi , Elvira Agron , Wai T. Wong , Emily Y. Chew , Zhiyong Lu

Objective: The advent of Electronic Medical Records (EMR) with large electronic imaging databases along with advances in deep neural networks with machine learning has provided a unique opportunity to achieve milestones in automated image…

机器学习 · 统计学 2016-12-16 Cecilia S. Lee , Doug M. Baughman , Aaron Y. Lee

Optical coherence tomography angiography (OCTA) provides non-invasive visualization of retinal microvasculature, but learning robust representations remains challenging due to sparse vessel structures and strong topological constraints.…

计算机视觉与模式识别 · 计算机科学 2026-04-09 Ilerioluwakiiye Abolade , Prince Mireku , Kelechi Chibundu , Peace Ododo , Emmanuel Idoko , Promise Omoigui , Solomon Odelola

Alterations in retinal layer thickness, measurable using Optical Coherence Tomography (OCT), have been associated with neurodegenerative diseases such as Alzheimer's disease (AD). While previous studies have mainly focused on segmented…

计算机视觉与模式识别 · 计算机科学 2025-11-10 Yasemin Turkan , F. Boray Tek , M. Serdar Nazlı , Öykü Eren

Purpose: This study explores the feasibility of using generative machine learning (ML) to translate Optical Coherence Tomography (OCT) images into Optical Coherence Tomography Angiography (OCTA) images, potentially bypassing the need for…

计算机视觉与模式识别 · 计算机科学 2024-04-26 Rashadul Hasan Badhon , Atalie Carina Thompson , Jennifer I. Lim , Theodore Leng , Minhaj Nur Alam
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