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We study continued training and supervised fine-tuning (SFT) of a language model (LM) to make effective use of long-context information. We first establish a reliable evaluation protocol to guide model development -- instead of perplexity…

计算与语言 · 计算机科学 2025-12-04 Tianyu Gao , Alexander Wettig , Howard Yen , Danqi Chen

Diagnosing esophageal motility disorders pose significant challenges due to the complexity of high-resolution impedance manometry (HRIM) data and variability in clinical interpretation. This work explores the feasibility of a multimodal…

机器学习 · 计算机科学 2026-05-14 Alexander Geiger , Lars Wagner , Daniel Rueckert , Alois Knoll , Dirk Wilhelm , Alissa Jell

Early detection of preventable diseases is important for better disease management, improved inter-ventions, and more efficient health-care resource allocation. Various machine learning approacheshave been developed to utilize information…

机器学习 · 计算机科学 2018-08-16 Jingshu Liu , Zachariah Zhang , Narges Razavian

Large language models have shown success as a tutor in education in various fields. Educating patients about their clinical visits plays a pivotal role in patients' adherence to their treatment plans post-discharge. This paper presents…

计算与语言 · 计算机科学 2023-10-31 Zihao Zhang , Zonghai Yao , Huixue Zhou , Feiyun ouyang , Hong Yu

Transformers have significantly advanced the modeling of Electronic Health Records (EHR), yet their deployment in real-world healthcare is limited by several key challenges. Firstly, the quadratic computational cost and insufficient context…

机器学习 · 计算机科学 2024-11-18 Adibvafa Fallahpour , Mahshid Alinoori , Wenqian Ye , Xu Cao , Arash Afkanpour , Amrit Krishnan

Proteins adopt multiple structural conformations to perform their diverse biological functions, and understanding these conformations is crucial for advancing drug discovery. Traditional physics-based simulation methods often struggle with…

生物大分子 · 定量生物学 2025-03-14 Jiarui Lu , Xiaoyin Chen , Stephen Zhewen Lu , Chence Shi , Hongyu Guo , Yoshua Bengio , Jian Tang

Large language models (LLMs) show promise for health applications when combined with behavioral sensing data. Traditional approaches convert sensor data into text prompts, but this process is prone to errors, computationally expensive, and…

In recent years, there has been a growing interest in integrating linear state-space models (SSM) in deep neural network architectures of foundation models. This is exemplified by the recent success of Mamba, showing better performance than…

系统与控制 · 电气工程与系统科学 2024-03-26 Carmen Amo Alonso , Jerome Sieber , Melanie N. Zeilinger

Pre-trained transformer language models (LMs) have in recent years become the dominant paradigm in applied NLP. These models have achieved state-of-the-art performance on tasks such as information extraction, question answering, sentiment…

计算与语言 · 计算机科学 2025-04-14 Aidan Mannion , Thierry Chevalier , Didier Schwab , Lorraine Geouriot

We introduce Synthetic Bootstrapped Pretraining (SBP), a language model (LM) pretraining procedure that first learns a model of relations between documents from the pretraining dataset and then leverages it to synthesize a vast new corpus…

计算与语言 · 计算机科学 2025-12-16 Zitong Yang , Aonan Zhang , Hong Liu , Tatsunori Hashimoto , Emmanuel Candès , Chong Wang , Ruoming Pang

Clinical language models have achieved strong performance on downstream tasks by pretraining on domain specific corpora such as discharge summaries and medical notes. However, most approaches treat the electronic health record as a static…

计算与语言 · 计算机科学 2025-04-28 Tatsunori Tanaka , Fi Zheng , Kai Sato , Zhifeng Li , Yuanyun Zhang , Shi Li

Early event prediction (EEP) systems continuously estimate a patient's imminent risk to support clinical decision-making. For bedside trust, risk trajectories must be accurate and temporally stable, shifting only with new, relevant…

机器学习 · 计算机科学 2025-10-17 Mayank Keoliya , Seewon Choi , Rajeev Alur , Mayur Naik , Eric Wong

Deep learning models have shown tremendous potential in learning representations, which are able to capture some key properties of the data. This makes them great candidates for transfer learning: Exploiting commonalities between different…

Massively multilingual sentence representation models, e.g., LASER, SBERT-distill, and LaBSE, help significantly improve cross-lingual downstream tasks. However, the use of a large amount of data or inefficient model architectures results…

计算与语言 · 计算机科学 2024-05-31 Zhuoyuan Mao , Chenhui Chu , Sadao Kurohashi

In medical information extraction, medical Named Entity Recognition (NER) is indispensable, playing a crucial role in developing medical knowledge graphs, enhancing medical question-answering systems, and analyzing electronic medical…

计算与语言 · 计算机科学 2024-03-26 Xiaojing Du , Hanjie Zhao , Danyan Xing , Yuxiang Jia , Hongying Zan

Large Language Models (LLMs) have shown strong promise for mining Electronic Health Records (EHRs) by reasoning over longitudinal clinical information to capture context-rich patient trajectories. However, leveraging LLMs for structured…

计算与语言 · 计算机科学 2026-04-21 Arya Hadizadeh Moghaddam , Drew Ross , Mohsen Nayebi Kerdabadi , Dongjie Wang , Zijun Yao

Contemporary large language models (LLMs) may have utility for processing unstructured, narrative free-text clinical data contained in electronic health records (EHRs) -- a particularly important use-case for mental health where a majority…

人工智能 · 计算机科学 2024-04-01 Niall Taylor , Andrey Kormilitzin , Isabelle Lorge , Alejo Nevado-Holgado , Dan W Joyce

Traditional topic models often struggle with contextual nuances and fail to adequately handle polysemy and rare words. This limitation typically results in topics that lack coherence and quality. Large Language Models (LLMs) can mitigate…

计算与语言 · 计算机科学 2025-05-13 Hajar Sakai , Sarah S. Lam

Research is a tertiary priority in the EHR, where the priorities are patient care and billing. Because of this, the data is not standardized or formatted in a manner easily adapted to machine learning approaches. Data may be missing for a…

机器学习 · 计算机科学 2017-07-25 Brett K. Beaulieu-Jones

Survival prediction is a crucial task associated with cancer diagnosis and treatment planning. This paper presents a novel approach to survival prediction by harnessing comprehensive information from CT and PET scans, along with associated…

图像与视频处理 · 电气工程与系统科学 2024-10-01 Aiman Farooq , Deepak Mishra , Santanu Chaudhury