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Survival prediction is an important branch of cancer prognosis analysis. The model that predicts survival risk through TCGA genomics data can discover genes related to cancer and provide diagnosis and treatment recommendations based on…

机器学习 · 计算机科学 2024-05-14 Wankang Zhai

Survival time prediction from medical images is important for treatment planning, where accurate estimations can improve healthcare quality. One issue affecting the training of survival models is censored data. Most of the current survival…

计算机视觉与模式识别 · 计算机科学 2022-05-27 Renato Hermoza , Gabriel Maicas , Jacinto C. Nascimento , Gustavo Carneiro

Survival prognosis is crucial for medical informatics. Practitioners often confront small-sized clinical data, especially cancer patient cases, which can be insufficient to induce useful patterns for survival predictions. This study deals…

机器学习 · 计算机科学 2025-01-23 Yonghao Zhao , Changtao Li , Chi Shu , Qingbin Wu , Hong Li , Chuan Xu , Tianrui Li , Ziqiang Wang , Zhipeng Luo , Yazhou He

Recent radiomic studies have witnessed promising performance of deep learning techniques in learning radiomic features and fusing multimodal imaging data. Most existing deep learning based radiomic studies build predictive models in a…

计算机视觉与模式识别 · 计算机科学 2019-01-08 Hongming Li , Pamela Boimel , James Janopaul-Naylor , Haoyu Zhong , Ying Xiao , Edgar Ben-Josef , Yong Fan

Survival analysis often relies on Cox models, assuming both linearity and proportional hazards (PH). This study evaluates machine and deep learning methods that relax these constraints, comparing their performance with penalized Cox models…

机器学习 · 计算机科学 2025-10-21 Ivan Rossi , Flavio Sartori , Cesare Rollo , Giovanni Birolo , Piero Fariselli , Tiziana Sanavia

Cancer survival prediction is an active area of research that can help prevent unnecessary therapies and improve patient's quality of life. Gene expression profiling is being widely used in cancer studies to discover informative biomarkers…

机器学习 · 计算机科学 2016-11-18 Hamid Reza Hassanzadeh , John H. Phan , May D. Wang

Objectives: Lung cancer poses a significant global health challenge, necessitating improved prognostic methods for personalized treatment. This study introduces a censor-aware semi-supervised learning (SSL) framework that integrates…

Cox proportional hazard model (CPH) is commonly used in clinical research for survival analysis. In quantitative medical imaging (radiomics) studies, CPH plays an important role in feature reduction and modeling. However, the underlying…

Prediction of survival for cancer patients is an open area of research. However, many of these studies focus on datasets with a large number of patients. We present a novel method that is specifically designed to address the challenge of…

机器学习 · 计算机科学 2015-09-30 Hamid Reza Hassanzadeh , John H. Phan , May D. Wang

Contrastive, self-supervised learning (SSL) is used to train a model that predicts cancer type from miRNA, mRNA or RPPA expression data. This model, a pretrained FT-Transformer, is shown to outperform XGBoost and CatBoost, standard…

机器学习 · 计算机科学 2023-11-17 Christian John Hurry , Emma Slade

The Cox proportional hazards (CPH) model has been widely applied in survival analysis to estimate relative risks across different subjects given multiple covariates. Traditional CPH models rely on a linear combination of covariates weighted…

机器学习 · 计算机科学 2025-04-28 Jiaxiang Cheng , Guoqiang Hu

The Cox Proportional Hazards (CPH) model has long been the preferred survival model for its explainability. However, to increase its predictive power beyond its linear log-risk, it was extended to utilize deep neural networks, sacrificing…

机器学习 · 计算机科学 2025-12-02 Abdallah Alabdallah , Omar Hamed , Mattias Ohlsson , Thorsteinn Rögnvaldsson , Sepideh Pashami

For predicting cancer survival outcomes, standard approaches in clinical research are often based on two main modalities: pathology images for observing cell morphology features, and genomic (e.g., bulk RNA-seq) for quantifying gene…

计算机视觉与模式识别 · 计算机科学 2024-03-19 Hongxiao Wang , Yang Yang , Zhuo Zhao , Pengfei Gu , Nishchal Sapkota , Danny Z. Chen

Although the Cox proportional hazards model is well established and extensively used in the analysis of survival data, the proportional hazards (PH) assumption may not always hold in practical scenarios. The class of semiparametric…

统计方法学 · 统计学 2025-10-21 Junkai Yin , Yue Zhang , Zhangsheng Yu

Background: CT imaging is vital for lung cancer management, offering detailed visualization for AI-based prognosis. However, supervised learning SL models require large labeled datasets, limiting their real-world application in settings…

Objective: This study explores a semi-supervised learning (SSL), pseudo-labeled strategy using diverse datasets to enhance lung cancer (LCa) survival predictions, analyzing Handcrafted and Deep Radiomic Features (HRF/DRF) from PET/CT scans…

计算机视觉与模式识别 · 计算机科学 2024-12-03 Mohammad R. Salmanpour , Arman Gorji , Amin Mousavi , Ali Fathi Jouzdani , Nima Sanati , Mehdi Maghsudi , Bonnie Leung , Cheryl Ho , Ren Yuan , Arman Rahmim

We explore whether survival model performance in underrepresented high- and low-risk subgroups - regions of the prognostic spectrum where clinical decisions are most consequential - can be improved through targeted restructuring of the…

Prognostic information at diagnosis has important implications for cancer treatment and monitoring. Although cancer staging, histopathological assessment, molecular features, and clinical variables can provide useful prognostic insights,…

When oncologists estimate cancer patient survival, they rely on multimodal data. Even though some multimodal deep learning methods have been proposed in the literature, the majority rely on having two or more independent networks that share…

图像与视频处理 · 电气工程与系统科学 2022-09-13 Numan Saeed , Ikboljon Sobirov , Roba Al Majzoub , Mohammad Yaqub

Most prediction models that are used in medical research fail to accurately predict health outcomes due to methodological limitations. Using routinely collected patient data, we explore the use of a Cox proportional hazard (PH) model within…

统计方法学 · 统计学 2019-07-19 John Mbotwa , Marc de Kamps , Paul D. Baxter , Mark S. Gilthorpe
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