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Label-free tomographic microscopy offers a compelling means to visualize three-dimensional (3D) refractive index (RI) distributions from two-dimensional (2D) intensity measurements. However, limited forward-model accuracy and the ill-posed…

光学 · 物理学 2025-02-27 Delong Yang , Shaohui Zhang , Jiasong Sun , Chao Zuo , Qun Hao

Knowledge of optical properties, such as the refractive index (RI), of biological tissues is important in optical imaging, as they influence the distribution and propagation of light in tissue. To accurately study the response of cancerous…

生物物理 · 物理学 2019-04-10 Neelam Hari , Priyanka Patel , Jacqueline Ross , Kevin Hicks , Frédérique Vanholsbeeck

The choroid provides oxygen and nourishment to the outer retina thus is related to the pathology of various ocular diseases. Optical coherence tomography (OCT) is advantageous in visualizing and quantifying the choroid in vivo. (1) The…

图像与视频处理 · 电气工程与系统科学 2020-09-09 Huihong Zhang , Jianlong Yang , Kang Zhou , Fei Li , Yan Hu , Yitian Zhao , Ce Zheng , Xiulan Zhang , Jiang Liu

In numerous applications, Fourier-domain optical coherence tomography (FD-OCT) suffers from a limited imaging depth due to signal roll-off, a limited focal range, and autocorrelation noise. Here, we propose a parallel full-field FD-OCT…

Optical link tomography (OLT) is a rapidly evolving field that allows the multi-span, end-to-end visualization of optical power along fiber links in multiple dimensions from network endpoints, solely by processing signals received at…

Optical transition radiation interferometry (OTRI) has been shown to be a very useful technique to measure the divergence of electron beams with energies in the range of 15-100 MeV. However, application of this method to low energy or very…

加速器物理 · 物理学 2007-05-23 A. G. Shkvarunets , R. B. Fiorito , P. G. O'Shea

Light scattering imposes a major obstacle for imaging objects seated deeply in turbid media, such as biological tissues and foggy air. Diffuse optical tomography (DOT) tackles scattering by volumetrically recovering the optical absorbance…

Simultaneous imaging of fluorescence-labeled and label-free phase objects in the same sample provides distinct and complementary information. Most multimodal fluorescence-phase imaging operates in transmission mode, capturing fluorescence…

光学 · 物理学 2024-08-20 Renzhi He , Yucheng Li , Junjie Chen , Yi Xue

Optical diffraction tomography relies on solving an inverse scattering problem governed by the wave equation. Classical reconstruction algorithms are based on linear approximations of the forward model (Born or Rytov), which limits their…

计算工程、金融与科学 · 计算机科学 2017-09-01 Emmanuel Soubies , Thanh-An Pham , Michael Unser

We present a tomographic imaging technique, termed Deep Prior Diffraction Tomography (DP-DT), to reconstruct the 3D refractive index (RI) of thick biological samples at high resolution from a sequence of low-resolution images collected…

图像与视频处理 · 电气工程与系统科学 2021-11-18 Kevin C. Zhou , Roarke Horstmeyer

Optical coherence tomography (OCT) is widely used for diagnosing and monitoring retinal diseases, such as age-related macular degeneration (AMD). The segmentation of biomarkers such as layers and lesions is essential for patient diagnosis…

计算机视觉与模式识别 · 计算机科学 2025-09-26 Botond Fazekas , Guilherme Aresta , Philipp Seeböck , Julia Mai , Ursula Schmidt-Erfurth , Hrvoje Bogunović

Spectral Domain Optical Coherence Tomography (SD-OCT) is a well-known imaging modality which allows for \textit{in-vivo} visualization of the morphology of different biological tissues at cellular level resolutions. The overall SD-OCT…

Optical Coherence Tomography (OCT) is a key 3D imaging technology that provides micron scale depth resolution for bio-imaging. This resolution substantially surpasses what it typically achieved in Light Detection and Ranging (LiDAR) which…

光学 · 物理学 2022-07-27 Robbie Murray , Ashley Lyons

Optical coherence tomography (OCT) is a micrometer-scale, volumetric imaging modality that has become a clinical standard in ophthalmology. OCT instruments image by raster-scanning a focused light spot across the retina, acquiring…

图像与视频处理 · 电气工程与系统科学 2022-09-16 Stefan Ploner , Siyu Chen , Jungeun Won , Lennart Husvogt , Katharina Breininger , Julia Schottenhamml , James Fujimoto , Andreas Maier

Optical Coherence Tomography (OCT) is a widely used non-invasive biomedical imaging modality that can rapidly provide volumetric images of samples. Here, we present a deep learning-based image reconstruction framework that can generate…

图像与视频处理 · 电气工程与系统科学 2021-07-30 Yijie Zhang , Tairan Liu , Manmohan Singh , Yilin Luo , Yair Rivenson , Kirill V. Larin , Aydogan Ozcan

Diffuse optical breast imaging utilizes near-infrared (NIR) light propagation through tissues to assess the optical properties of tissue for the identification of abnormal tissue. This optical imaging approach is sensitive, cost-effective,…

医学物理 · 物理学 2017-11-22 Wenxiang Cong , Xavier Intes , Ge Wang

We demonstrate a novel imaging approach and associated reconstruction algorithm for far-field coherent diffractive imaging, based on the measurement of a pair of laterally sheared diffraction patterns. The differential phase profile…

光学 · 物理学 2018-05-23 G. S. M. Jansen , A. C. C. de Beurs , X. Liu , K. S. E. Eikema , S. Witte

Optical coherence tomography (OCT) is a prevalent, interferometric, high-resolution imaging method with broad biomedical applications. Nonetheless, OCT images suffer from an artifact, called speckle which degrades the image quality. Digital…

The interest in using optical transition radiation (OTR) in high energy (multiGeV) beam diagnostics has motivated theoretical and experimental investigations on the limitations brought by diffraction on the attainable resolution. This paper…

加速器物理 · 物理学 2007-05-23 X. Artru , R. Chehab , K. Honkavaara , A. Variola

Optical coherence tomography (OCT) image analysis plays an important role in the field of ophthalmology. Current successful analysis models rely on available large datasets, which can be challenging to be obtained for certain tasks. The use…

图像与视频处理 · 电气工程与系统科学 2024-05-28 Kun Huang , Xiao Ma , Yuhan Zhang , Na Su , Songtao Yuan , Yong Liu , Qiang Chen , Huazhu Fu