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Representation learning offers a conduit to elucidate distinctive features within the latent space and interpret the deep models. However, the randomness of lesion distribution and the complexity of low-quality factors in medical images…

计算机视觉与模式识别 · 计算机科学 2024-04-09 Qingshan Hou , Shuai Cheng , Peng Cao , Jinzhu Yang , Xiaoli Liu , Osmar R. Zaiane , Yih Chung Tham

Class-incremental learning (CIL) enables models to continuously learn new categories from sequential tasks without forgetting previously acquired knowledge. While recent advances in vision-language models such as CLIP have demonstrated…

计算机视觉与模式识别 · 计算机科学 2025-11-17 Haoran Chen , Houze Xu , Micah Goldblum , Daoguo Dong , Zuxuan Wu

Deep learning models have revolutionized the field of medical image analysis, due to their outstanding performances. However, they are sensitive to spurious correlations, often taking advantage of dataset bias to improve results for…

计算机视觉与模式识别 · 计算机科学 2024-05-06 Diogo J. Araújo , M. Rita Verdelho , Alceu Bissoto , Jacinto C. Nascimento , Carlos Santiago , Catarina Barata

Weakly-supervised classification of histopathology slides is a computationally intensive task, with a typical whole slide image (WSI) containing billions of pixels to process. We propose Discriminative Region Active Sampling for Multiple…

图像与视频处理 · 电气工程与系统科学 2023-02-23 Jack Breen , Katie Allen , Kieran Zucker , Geoff Hall , Nicolas M. Orsi , Nishant Ravikumar

When applying multi-instance learning (MIL) to make predictions for bags of instances, the prediction accuracy of an instance often depends on not only the instance itself but also its context in the corresponding bag. From the viewpoint of…

计算机视觉与模式识别 · 计算机科学 2022-04-25 Tiancheng Lin , Hongteng Xu , Canqian Yang , Yi Xu

In histopathology, intelligent diagnosis of Whole Slide Images (WSIs) is essential for automating and objectifying diagnoses, reducing the workload of pathologists. However, diagnostic models often face the challenge of forgetting…

计算机视觉与模式识别 · 计算机科学 2025-03-26 Weixi Zheng , Aoling Huang , Jingping Yuan , Haoyu Zhao , Zhou Zhao , Yongchao Xu , Thierry Géraud

Federated learning enables collaborative model training across geographically distributed medical centers while preserving data privacy. However, domain shifts and heterogeneity in data often lead to a degradation in model performance.…

Objective: We aimed to develop and validate a novel multimodal framework HiMAL (Hierarchical, Multi-task Auxiliary Learning) framework, for predicting cognitive composite functions as auxiliary tasks that estimate the longitudinal risk of…

机器学习 · 计算机科学 2026-02-06 Sayantan Kumar , Sean Yu , Andrew Michelson , Thomas Kannampallil , Philip Payne

Learning representations that transfer well to diverse downstream tasks remains a central challenge in representation learning. Existing paradigms -- contrastive learning, self-supervised masking, and denoising auto-encoders -- balance this…

机器学习 · 计算机科学 2025-09-29 Micha Livne

Multi-instance learning is common for computer vision tasks, especially in biomedical image processing. Traditional methods for multi-instance learning focus on designing feature aggregation methods and multi-instance classifiers, where the…

计算机视觉与模式识别 · 计算机科学 2021-03-18 Yanlun Tu , Houchao Lei , Wei Long , Yang Yang

Accurate classification of Intraductal Papillary Mucinous Neoplasms (IPMN) is essential for identifying high-risk cases that require timely intervention. In this study, we develop a federated learning framework for multi-center IPMN…

Vision-language models (VLMs) have recently been integrated into multiple instance learning (MIL) frameworks to address the challenge of few-shot, weakly supervised classification of whole slide images (WSIs). A key trend involves…

计算机视觉与模式识别 · 计算机科学 2025-12-15 Bryan Wong , Jong Woo Kim , Huazhu Fu , Mun Yong Yi

Mammograms are commonly employed in the large scale screening of breast cancer which is primarily characterized by the presence of malignant masses. However, automated image-level detection of malignancy is a challenging task given the…

计算机视觉与模式识别 · 计算机科学 2020-04-27 Sarath Chandra K , Arunava Chakravarty , Nirmalya Ghosh , Tandra Sarkar , Ramanathan Sethuraman , Debdoot Sheet

Histopathological whole slide image (WSI) analysis with deep learning has become a research focus in computational pathology. The current paradigm is mainly based on multiple instance learning (MIL), in which approaches with Transformer as…

计算机视觉与模式识别 · 计算机科学 2024-03-19 Hongbo Chu , Qiehe Sun , Jiawen Li , Yuxuan Chen , Lizhong Zhang , Tian Guan , Anjia Han , Yonghong He

Recently, pathological diagnosis has achieved superior performance by combining deep learning models with the multiple instance learning (MIL) framework using whole slide images (WSIs). However, the giga-pixeled nature of WSIs poses a great…

计算机视觉与模式识别 · 计算机科学 2024-10-31 Zijie Fang , Yifeng Wang , Ye Zhang , Zhi Wang , Jian Zhang , Xiangyang Ji , Yongbing Zhang

Histopathology image analysis plays a critical role in cancer diagnosis and treatment. To automatically segment the cancerous regions, fully supervised segmentation algorithms require labor-intensive and time-consuming labeling at the pixel…

图像与视频处理 · 电气工程与系统科学 2019-08-29 Gang Xu , Zhigang Song , Zhuo Sun , Calvin Ku , Zhe Yang , Cancheng Liu , Shuhao Wang , Jianpeng Ma , Wei Xu

Multiple Instance Learning (MIL) models have proven effective for cancer prognosis from Whole Slide Images. However, the original MIL formulation incorrectly assumes the patches of the same image to be independent, leading to a loss of…

计算机视觉与模式识别 · 计算机科学 2024-08-13 Thiziri Nait Saada , Valentina Di Proietto , Benoit Schmauch , Katharina Von Loga , Lucas Fidon

Histology images with multi-gigapixel of resolution yield rich information for cancer diagnosis and prognosis. Most of the time, only slide-level label is available because pixel-wise annotation is labour intensive task. In this paper, we…

计算机视觉与模式识别 · 计算机科学 2022-09-08 Made Satria Wibawa , Kwok-Wai Lo , Lawrence Young , Nasir Rajpoot

Estimating over-amplification of human epidermal growth factor receptor 2 (HER2) on invasive breast cancer (BC) is regarded as a significant predictive and prognostic marker. We propose a novel deep reinforcement learning (DRL) based model…

计算机视觉与模式识别 · 计算机科学 2019-03-27 Talha Qaiser , Nasir M. Rajpoot

Motivation: Multi-omics integration can improve cancer subtyping, but modality informativeness and noise vary across cancer types and patients. Existing graph-based methods optimize modality weights jointly with the classification objective…

机器学习 · 计算机科学 2026-04-28 Boyang Fan , Hengchuang Yin , Siyu Yi , Yifan Wang , Zhicheng Li , Leijiyu Zhou , Jiancheng Lv , Wei Ju