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Gliomas are the most common primary tumors of the central nervous system. Multimodal MRI is widely used for the preliminary screening of gliomas and plays a crucial role in auxiliary diagnosis, therapeutic efficacy, and prognostic…

图像与视频处理 · 电气工程与系统科学 2025-05-27 Yihao Liu , Zhihao Cui , Liming Li , Junjie You , Xinle Feng , Jianxin Wang , Xiangyu Wang , Qing Liu , Minghua Wu

Although melanoma occurs more rarely than several other skin cancers, patients' long term survival rate is extremely low if the diagnosis is missed. Diagnosis is complicated by a high discordance rate among pathologists when distinguishing…

计算机视觉与模式识别 · 计算机科学 2022-10-11 Sean Grullon , Vaughn Spurrier , Jiayi Zhao , Corey Chivers , Yang Jiang , Kiran Motaparthi , Michael Bonham , Julianna Ianni

Whole slide images (WSI) provide valuable phenotypic information for histological assessment and malignancy grading of tumors. The WSI-based grading promises to provide rapid diagnostic support and facilitate digital health. Currently, the…

图像与视频处理 · 电气工程与系统科学 2022-10-05 Lipei Zhang , Yiran Wei , Ying Fu , Stephen Price , Carola-Bibiane Schönlieb , Chao Li

Clinicians usually combine information from multiple sources to achieve the most accurate diagnosis, and this has sparked increasing interest in leveraging multimodal deep learning for diagnosis. However, in real clinical scenarios, due to…

计算机视觉与模式识别 · 计算机科学 2025-08-05 Kai Han , Chongwen Lyu , Lele Ma , Chengxuan Qian , Siqi Ma , Zheng Pang , Jun Chen , Zhe Liu

The detection of induced pluripotent stem cell (iPSC) colonies often needs the precise extraction of the colony features. However, existing computerized systems relied on segmentation of contours by preprocessing for classifying the colony…

图像与视频处理 · 电气工程与系统科学 2022-03-10 Novanto Yudistira , Muthu Subash Kavitha , Jeny Rajan , Takio Kurita

Multiple Instance Learning (MIL) has advanced WSI analysis but struggles with the complexity and heterogeneity of WSIs. Existing MIL methods face challenges in aggregating diverse patch information into robust WSI representations. While…

计算机视觉与模式识别 · 计算机科学 2025-07-28 Beidi Zhao , SangMook Kim , Hao Chen , Chen Zhou , Zu-hua Gao , Gang Wang , Xiaoxiao Li

Advances in medical imaging and deep learning have propelled progress in whole slide image (WSI) analysis, with multiple instance learning (MIL) showing promise for efficient and accurate diagnostics. However, conventional MIL models often…

计算机视觉与模式识别 · 计算机科学 2025-05-19 Xianrui Li , Yufei Cui , Jun Li , Antoni B. Chan

Deep neural network-based medical image classifications often use "hard" labels for training, where the probability of the correct category is 1 and those of others are 0. However, these hard targets can drive the networks over-confident…

计算机视觉与模式识别 · 计算机科学 2020-07-14 Dong Wei , Shilei Cao , Kai Ma , Yefeng Zheng

This paper reports the method and evaluation results of MedAusbild team for ISIC challenge task. Since early 2017, our team has worked on melanoma classification [1][6], and has employed deep learning since beginning of 2018 [7]. Deep…

机器学习 · 计算机科学 2018-07-25 Sara Nasiri , Matthias Jung , Julien Helsper , Madjid Fathi

Modern high-throughput sequencing technologies have enabled us to profile multiple molecular modalities from the same single cell, providing unprecedented opportunities to assay celluar heterogeneity from multiple biological layers.…

机器学习 · 统计学 2022-05-20 Pengcheng Zeng , Zhixiang Lin

Multimodal deep learning for cancer prognosis is commonly assumed to benefit from synergistic cross-modal interactions, yet this assumption has not been directly tested in survival prediction settings. This work adapts InterSHAP, a Shapley…

机器学习 · 计算机科学 2026-04-15 Iain Swift , JingHua Ye , Ruairi O'Reilly

The color of skin lesions is an important diagnostic feature for identifying malignant melanoma and other skin diseases. Typical colors associated with melanocytic lesions include tan, brown, black, red, white, and blue gray. This study…

定量方法 · 定量生物学 2026-01-30 M. A. Rasel , Sameem Abdul Kareem , Unaizah Obaidellah

Kinship verification is a long-standing research challenge in computer vision. The visual differences presented to the face have a significant effect on the recognition capabilities of the kinship systems. We argue that aggregating multiple…

计算机视觉与模式识别 · 计算机科学 2021-09-08 Guan-Nan Dong , Chi-Man Pun , Zheng Zhang

In this study, we introduce a multi-modal approach that efficiently integrates multi-scale clinical and dermoscopy features within a single network, thereby substantially reducing model parameters. The proposed method includes three novel…

图像与视频处理 · 电气工程与系统科学 2024-03-31 Peng Tang , Tobias Lasser

Multiple Instance Learning (MIL) is a sub-domain of classification problems with positive and negative labels and a "bag" of inputs, where the label is positive if and only if a positive element is contained within the bag, and otherwise is…

机器学习 · 统计学 2023-10-30 Edward Raff , James Holt

Malignant brain tumors have become an aggressive and dangerous disease that leads to death worldwide.Multi-modal MRI data is crucial for accurate brain tumor segmentation, but missing modalities common in clinical practice can severely…

统计方法学 · 统计学 2025-07-11 Guoyan Liang , Qin Zhou , Jingyuan Chen , Bingcang Huang , Kai Chen , Lin Gu , Zhe Wang , Sai Wu , Chang Yao

Colorectal cancer is one of the most common and lethal cancers and colorectal cancer liver metastases (CRLM) is the major cause of death in patients with colorectal cancer. Multifocality occurs frequently in CRLM, but is relatively…

计算机视觉与模式识别 · 计算机科学 2021-07-13 Jianan Chen , Helen M. C. Cheung , Laurent Milot , Anne L. Martel

Deep models, e.g., CNNs and Vision Transformers, have achieved impressive achievements in many vision tasks in the closed world. However, novel classes emerge from time to time in our ever-changing world, requiring a learning system to…

计算机视觉与模式识别 · 计算机科学 2024-07-16 Da-Wei Zhou , Qi-Wei Wang , Zhi-Hong Qi , Han-Jia Ye , De-Chuan Zhan , Ziwei Liu

Multi-domain task-incremental learning requires a model to sequentially acquire knowledge across visually diverse domains without forgetting prior tasks, and without access to task identity at inference. Parameter-efficient methods built on…

计算机视觉与模式识别 · 计算机科学 2026-05-26 Sriram Mandalika

Multi-instance learning (MIL) is a widely-applied technique in practical applications that involve complex data structures. MIL can be broadly categorized into two types: traditional methods and those based on deep learning. These…

人工智能 · 计算机科学 2023-04-25 Yu-Xuan Zhang , Zhengchun Zhou , Xingxing He , Avik Ranjan Adhikary , Bapi Dutta