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Learning representations for individual instances when only bag-level labels are available is a fundamental challenge in multiple instance learning (MIL). Recent works have shown promising results using contrastive self-supervised learning…

计算机视觉与模式识别 · 计算机科学 2023-07-13 Kangning Liu , Weicheng Zhu , Yiqiu Shen , Sheng Liu , Narges Razavian , Krzysztof J. Geras , Carlos Fernandez-Granda

Accurate skin disease classification is a critical yet challenging task due to high inter-class similarity, intra-class variability, and complex lesion textures. While deep learning-based computer-aided diagnosis (CAD) systems have shown…

计算机视觉与模式识别 · 计算机科学 2025-08-07 Enam Ahmed Taufik , Abdullah Khondoker , Antara Firoz Parsa , Seraj Al Mahmud Mostafa

A significant challenge in solid tumors is reliably distinguishing confounding pathologies from malignant neoplasms on routine imaging. While radiomics methods seek surrogate markers of lesion heterogeneity on CT/MRI, many aggregate…

We introduce ReaMIL (Reasoning- and Evidence-Aware MIL), a multiple instance learning approach for whole-slide histopathology that adds a light selection head to a strong MIL backbone. The head produces soft per-tile gates and is trained…

计算机视觉与模式识别 · 计算机科学 2026-04-08 Hyun Do Jung , Jungwon Choi , Hwiyoung Kim

Recent advances in image-text pretraining have significantly enhanced visual understanding by aligning visual and textual representations. Contrastive Language-Image Pretraining (CLIP) has played a pivotal role in multimodal learning.…

计算机视觉与模式识别 · 计算机科学 2026-02-20 Zihan Li , Yiqing Wang , Sina Farsiu , Paul Kinahan

Histology analysis of the tumor micro-environment integrated with genomic assays is the gold standard for most cancers in modern medicine. This paper proposes a Gene-induced Multimodal Pre-training (GiMP) framework, which jointly…

计算机视觉与模式识别 · 计算机科学 2023-09-07 Ting Jin , Xingran Xie , Renjie Wan , Qingli Li , Yan Wang

Retinal diseases spanning a broad spectrum can be effectively identified and diagnosed using complementary signals from multimodal data. However, multimodal diagnosis in ophthalmic practice is typically challenged in terms of data…

计算机视觉与模式识别 · 计算机科学 2026-02-04 Lu Zhang , Huizhen Yu , Zuowei Wang , Fu Gui , Yatu Guo , Wei Zhang , Mengyu Jia

Multiple instance learning (MIL) is often used in medical imaging to classify high-resolution 2D images by processing patches or classify 3D volumes by processing slices. However, conventional MIL approaches treat instances separately,…

机器学习 · 计算机科学 2025-11-13 Ethan Harvey , Dennis Johan Loevlie , Michael C. Hughes

Objectives We aimed to evaluate the diagnostic performance of deep learning (DL)-based radiomics models for the noninvasive prediction of isocitrate dehydrogenase (IDH) mutation and 1p/19q co-deletion status in glioma patients using MRI…

定量方法 · 定量生物学 2025-08-19 Somayeh Farahani , Marjaneh Hejazi , Mehnaz Tabassum , Antonio Di Ieva , Neda Mahdavifar , Sidong Liu

White matter hyperintensities (WMH) are radiological markers of small vessel disease and neurodegeneration, whose accurate segmentation and spatial localization are crucial for diagnosis and monitoring. While multimodal MRI offers…

图像与视频处理 · 电气工程与系统科学 2025-06-30 Julia Machnio , Sebastian Nørgaard Llambias , Mads Nielsen , Mostafa Mehdipour Ghazi

Deep neural networks (DNNs) have promoted the development of computer aided diagnosis (CAD) systems for fundus diseases, helping ophthalmologists reduce missed diagnosis and misdiagnosis rate. However, the majority of CAD systems are…

图像与视频处理 · 电气工程与系统科学 2023-04-26 Hongyang Jiang , Jingqi Huang , Chen Tang , Xiaoqing Zhang , Mengdi Gao , Jiang Liu

The survival analysis on histological whole-slide images (WSIs) is one of the most important means to estimate patient prognosis. Although many weakly-supervised deep learning models have been developed for gigapixel WSIs, their potential…

图像与视频处理 · 电气工程与系统科学 2023-11-06 Pei Liu , Luping Ji , Feng Ye , Bo Fu

Purpose: Multiple sclerosis (MS) diagnosis requires accurate assessment of white matter hyperintensities (WMH) and ventricular changes on brain MRI. Current methods treat these structures independently, struggle to differentiate normal from…

图像与视频处理 · 电气工程与系统科学 2026-02-20 Mahdi Bashiri Bawil , Mousa Shamsi , Abolhassan Shakeri Bavil

Multiple Instance Learning (MIL) plays a significant role in computational pathology, enabling weakly supervised analysis of Whole Slide Image (WSI) datasets. The field of WSI analysis is confronted with a severe long-tailed distribution…

计算机视觉与模式识别 · 计算机科学 2025-03-04 Xitong Ling , Yifeng Ping , Jiawen Li , Jing Peng , Yuxuan Chen , Minxi Ouyang , Yizhi Wang , Yonghong He , Tian Guan , Xiaoping Liu , Lianghui Zhu

This study focuses on incremental learning for image classification, exploring how to reduce catastrophic forgetting of all learned knowledge when access to old data is restricted. The challenge lies in balancing plasticity (learning new…

机器学习 · 计算机科学 2026-03-12 Zhiping Zhou , Xuchen Xie , Yiqiao Qiu , Run Lin , Weishi Zheng , Ruixuan Wang

Skin lesion identification is a key step toward dermatological diagnosis. When describing a skin lesion, it is very important to note its body site distribution as many skin diseases commonly affect particular parts of the body. To exploit…

计算机视觉与模式识别 · 计算机科学 2022-03-24 Haofu Liao , Jiebo Luo

Deep learning implemented with convolutional network architectures can exceed specialists' diagnostic accuracy. However, whole-image deep learning trained on a given dataset may not generalize to other datasets. The problem arises because…

计算机视觉与模式识别 · 计算机科学 2023-05-17 Norsang Lama , R. Joe Stanley , Anand Nambisan , Akanksha Maurya , Jason Hagerty , William V. Stoecker

While deep learning based approaches have demonstrated expert-level performance in dermatological diagnosis tasks, they have also been shown to exhibit biases toward certain demographic attributes, particularly skin types (e.g., light…

计算机视觉与模式识别 · 计算机科学 2022-08-30 Arezou Pakzad , Kumar Abhishek , Ghassan Hamarneh

The presence of certain clinical dermoscopic features within a skin lesion may indicate melanoma, and automatically detecting these features may lead to more quantitative and reproducible diagnoses. We reformulate the task of classifying…

计算机视觉与模式识别 · 计算机科学 2019-03-28 Jeremy Kawahara , Ghassan Hamarneh

The global prevalence of dementia is projected to double by 2050, highlighting the urgent need for scalable diagnostic tools. This study utilizes digital cognitive tasks with eye-tracking data correlated with memory processes to distinguish…

人机交互 · 计算机科学 2025-08-28 Tomás Silva Santos Rocha , Anastasiia Mikhailova , Moreno I. Coco , José Santos-Victor
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