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As very large studies of complex neuroimaging phenotypes become more common, human quality assessment of MRI-derived data remains one of the last major bottlenecks. Few attempts have so far been made to address this issue with machine…

Immunohistochemical (IHC) images reveal detailed information about structures and functions at the subcellular level. However, unlike natural images, IHC datasets pose challenges for deep learning models due to their inconsistencies in…

计算机视觉与模式识别 · 计算机科学 2025-05-27 Umar Marikkar , Syed Sameed Husain , Muhammad Awais , Sara Atito

Magnetic particle imaging (MPI) is a non-invasive, non-ionizing imaging technique for the visualization and quantification of magnetic nanoparticles (MNPs). The technique is especially suitable for cell imaging as it offers zero background…

Despite the promise of computational pathology foundation models, adapting them to specific clinical tasks remains challenging due to the complexity of whole-slide image (WSI) processing, the opacity of learned features, and the wide range…

计算机视觉与模式识别 · 计算机科学 2025-11-26 Abdul Rahman Diab , Emily E. Karn , Renchin Wu , Emily S. Ruiz , William Lotter

Image analysis using more than one modality (i.e. multi-modal) has been increasingly applied in the field of biomedical imaging. One of the challenges in performing the multimodal analysis is that there exist multiple schemes for fusing the…

计算机视觉与模式识别 · 计算机科学 2018-06-19 Zhe Guo , Xiang Li , Heng Huang , Ning Guo , Quanzheng Li

Effective dietary monitoring is critical for managing Type 2 diabetes, yet accurately estimating caloric intake remains a major challenge. While continuous glucose monitors (CGMs) offer valuable physiological data, they often fall short in…

计算机视觉与模式识别 · 计算机科学 2025-05-21 Adarsh Kumar

Models for segmentation of brain lesions in multi-modal MRI are commonly trained for a specific pathology using a single database with a predefined set of MRI modalities, determined by a protocol for the specific disease. This work explores…

The automated analysis of microscopy images is a challenge in the context of single-cell tracking and quantification. This work has as goals the study of the performance of deep learning for segmenting microscopy images and the improvement…

定量方法 · 定量生物学 2022-10-05 André O. Françani

The application of machine learning techniques to the medical domain is especially challenging due to the required level of precision and the incurrence of huge risks of minute errors. Employing these techniques to a more complex subdomain…

计算机视觉与模式识别 · 计算机科学 2021-10-19 Ekta Gavas , Kaustubh Olpadkar

In this study, we introduce a multi-modal approach that efficiently integrates multi-scale clinical and dermoscopy features within a single network, thereby substantially reducing model parameters. The proposed method includes three novel…

图像与视频处理 · 电气工程与系统科学 2024-03-31 Peng Tang , Tobias Lasser

Mathematical morphology is a theory and technique to collect features like geometric and topological structures in digital images. Given a target image, determining suitable morphological operations and structuring elements is a cumbersome…

计算机视觉与模式识别 · 计算机科学 2019-09-05 Yucong Shen , Xin Zhong , Frank Y. Shih

For over two decades, image-based profiling has revolutionized cell phenotype analysis. Image-based profiling processes rich, high-throughput, microscopy data into thousands of unbiased measurements that reveal phenotypic patterns powerful…

Foundation models are reshaping computational pathology by enabling transfer learning, where models pre-trained on vast datasets can be adapted for downstream diagnostic, prognostic, and therapeutic response tasks. Despite these advances,…

High-throughput biological imaging is often constrained by a trade-off between acquisition speed and image quality. Fast imaging modalities, such as wide-field fluorescence microscopy, enable large-scale data acquisition but suffer from…

图像与视频处理 · 电气工程与系统科学 2026-04-20 Dominik Panek , Carina Rząca , Maksymilian Szczypior , Joanna Sorysz , Krzysztof Misztal , Zbigniew Baster , Zenon Rajfur

Conventional histopathology has long been essential for disease diagnosis, relying on visual inspection of tissue sections. Immunohistochemistry aids in detecting specific biomarkers but is limited by its single-marker approach, restricting…

Electropermeabilization is a clinical technique in cancer treatment to locally stimulate the cell metabolism. It is based on electrical fields that change the properties of the cell membrane. With that, cancer treatment can reach the cell…

偏微分方程分析 · 数学 2016-03-03 Habib Ammari , Thomas Widlak , Wenlong Zhang

In digital pathology, cell detection and classification are often prerequisites to quantify cell abundance and explore tissue spatial heterogeneity. However, these tasks are particularly challenging for multiplex immunohistochemistry (mIHC)…

图像与视频处理 · 电气工程与系统科学 2019-08-05 Yeman Brhane Hagos , Priya Lakshmi Narayanan , Ayse U. Akarca , Teresa Marafioti , Yinyin Yuan

This paper proposes a modified Topological Data Analysis model for skin images preprocessing and enhancements. The skin lesion dataset HAM10000 used with the intention of identifying the important objects in relevant regions of the images.…

计算机视觉与模式识别 · 计算机科学 2023-08-15 Hong Cheng , Rebekah Leamons , Ahmad Al Shami

Investigation of cell structure is hardly imaginable without bright-field microscopy. Numerous modifications such as depth-wise scanning or videoenhancement make this method being state-of-the-art. This raises a question what maximal…

图像与视频处理 · 电气工程与系统科学 2020-10-29 Kirill Lonhus , Renata Rychtarikova , Ganna Platonova , Dalibor Stys

Single-cell datasets often lack individual cell labels, making it challenging to identify cells associated with disease. To address this, we introduce Mixture Modeling for Multiple Instance Learning (MMIL), an expectation maximization…