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Task functional magnetic resonance imaging (fMRI) is a type of neuroimaging data used to identify areas of the brain that activate during specific tasks or stimuli. These data are conventionally modeled using a massive univariate approach…

统计方法学 · 统计学 2022-11-04 Daniel A. Spencer , David Bolin , Amanda F. Mejia

Multi-electrode arrays (MEAs) can record extracellular action potentials (also known as 'spikes') from hundreds or thousands of neurons simultaneously. Inference of a functional network from a spike train is a fundamental and formidable…

计算工程、金融与科学 · 计算机科学 2020-07-07 Yun Zhao , Richard Jiang , Zhenni Xu , Elmer Guzman , Paul K. Hansma , Linda Petzold

This thesis is dedicated to the statistical analysis of multi-sub ject fMRI data, with the purpose of identifying bain structures involved in certain cognitive or sensori-motor tasks, in a reproducible way across sub jects. To overcome…

应用统计 · 统计学 2010-05-19 Merlin Keller , Alexis Roche , Marc Lavielle

In this paper, we describe a Bayesian deep neural network (DNN) for predicting FreeSurfer segmentations of structural MRI volumes, in minutes rather than hours. The network was trained and evaluated on a large dataset (n = 11,480), obtained…

A major open challenge in neuroscience is the ability to measure and perturb neural activity in vivo from well-defined neural sub-populations at cellular resolution anywhere in the brain. However, limitations posed by scattering and…

生物物理 · 物理学 2017-11-10 Shay Ohayon , Antonio Miguel Caravaca-Aguirre , Rafael Piestun , James J. DiCarlo

(1) Background: The success of physiotherapy depends on the regular and correct performance of movement exercises. A system that automatically evaluates these could support the therapy. Previous approaches in this area rarely rely on Deep…

机器学习 · 计算机科学 2025-06-02 Andreas Spilz , MIchael Munz

Partial synchronization plays a crucial role in the functioning of neuronal networks: selective, coordinated activation of neurons enables information processing that flexibly adapts to a changing computational context. Since the structure…

神经元与认知 · 定量生物学 2025-06-17 Daniil Radushev , Olesia Dogonasheva , Boris Gutkin , Denis Zakharov

Activity detection is an important task in the next generation grant-free multiple access. While there are a number of existing algorithms designed for this purpose, they mostly require precise information about the network, such as…

机器学习 · 计算机科学 2024-02-05 Hao Zhang , Qingfeng Lin , Yang Li , Lei Cheng , Yik-Chung Wu

Calcium imaging is one of the most important tools in neurophysiology as it enables the observation of neuronal activity for hundreds of cells in parallel and at single-cell resolution. In order to use the data gained with calcium imaging,…

神经元与认知 · 定量生物学 2020-04-07 Elke Kirschbaum , Alberto Bailoni , Fred A. Hamprecht

Recently, fluorescence-based optical techniques have emerged as a powerful tool to probe information in the mammalian brain. However, tissue heterogeneities prevent clear imaging of deep neuron bodies due to light scattering. While several…

Extracting and detecting spike activities from the fluorescence observations is an important step in understanding how neuron systems work. The main challenge lies in that the combination of the ambient noise with dynamic baseline…

神经元与认知 · 定量生物学 2019-02-01 Zhuangkun Wei , Bin Li , Weisi Guo , Wenxiu Hu , Chenglin Zhao

Neurons encode information about the environment through their activity. As animals explore the environment, neurons rapidly acquire selectivity for distinct features of the external world; characterizing how these selectivity patterns…

Fluorescent calcium indicators are a popular means for observing the spiking activity of large neuronal populations, but extracting the activity of each neuron from raw fluorescence calcium imaging data is a nontrivial problem. We present a…

神经元与认知 · 定量生物学 2017-03-17 Johannes Friedrich , Pengcheng Zhou , Liam Paninski

Experiments that study neural encoding of stimuli at the level of individual neurons typically choose a small set of features present in the world --- contrast and luminance for vision, pitch and intensity for sound --- and assemble a…

机器学习 · 统计学 2016-11-22 Xin , Chen , Jeffrey M Beck , John M Pearson

In the recent past, psychological stress has been increasingly observed in humans, and early detection is crucial to prevent health risks. Stress detection using on-device deep learning algorithms has been on the rise owing to advancements…

机器学习 · 计算机科学 2020-12-07 Abhijith Ragav , Gautham Krishna Gudur

Advances in image registration and machine learning have recently enabled volumetric analysis of postmortem brain tissue from conventional photographs of coronal slabs, which are routinely collected in brain banks and neuropathology…

Semantic segmentation is a crucial task in biomedical image processing, which recent breakthroughs in deep learning have allowed to improve. However, deep learning methods in general are not yet widely used in practice since they require…

计算机视觉与模式识别 · 计算机科学 2019-07-12 Melanie Lubrano di Scandalea , Christian S. Perone , Mathieu Boudreau , Julien Cohen-Adad

Deep-learning algorithms enable precise image recognition based on high-dimensional hierarchical image features. Here, we report the development and implementation of a deep-learning-based image segmentation algorithm in an autonomous…

图像与视频处理 · 电气工程与系统科学 2020-03-26 Satoru Masubuchi , Eisuke Watanabe , Yuta Seo , Shota Okazaki , Takao Sasagawa , Kenji Watanabe , Takashi Taniguchi , Tomoki Machida

Various brain functions that are necessary to maintain life activities materialize through the interaction of countless neurons. Therefore, it is important to analyze functional neuronal network. To elucidate the mechanism of brain…

神经元与认知 · 定量生物学 2023-06-29 Shun Kimura , Koujin Takeda

3D functional imaging of neuronal activity in entire organisms at single cell level and physiologically relevant time scales faces major obstacles due to trade-offs between the size of the imaged volumes, and spatial and temporal…