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A fundamental, Quantum Mechanical description of photoactivation of a generic photosensitizer and the ensuing transfer of energy to endogenous oxygen as part of the Type II pathway to photodamage during photodynamic therapy (PDT) is…

医学物理 · 物理学 2023-01-11 Vincent M. Rossi

Quantum chemistry simulations offer a cost-effective way for computational design of BODIPY photosensitizers with potential use in photodynamic therapy (PDT). However, accurate predictions of photophysical properties, such as excitation…

Theranostics, the combination of diagnosis and therapy, has long held promise as a means to achieving personalised precision cancer treatments. However, despite its potential, theranostics has yet to realise significant clinical…

The system of partial differential equations describing tumor-immune dynamics with angiogenesis taken into account is presented. For spatially homogeneous case, the steady state analysis of the model is carried out. The effects of single…

细胞行为 · 定量生物学 2015-05-14 O. G. Isaeva , V. A. Osipov

Fusion-based quantum computing is an attractive model for fault-tolerant computation based on photonics requiring only finite-sized entangled resource states followed by linear-optics operations and photon measurements. Large-scale…

Iridium-based photosensitizers have attracted significant attention in photodynamic therapy (PDT) due to their exceptional photophysical properties and chemical stability, as well as tunable phosphorescence emission spectrum and high…

化学物理 · 物理学 2026-05-08 Aynur Matyusup , Jia-ying Zhao , Yu-dan Zhang , Qi Zhaoa , Ai-min Ren , Jing-fu Guo

Photon-counting computed tomography (PCCT) marks a significant advancement over conventional energy-integrating detector (EID) CT systems. This review highlights PCCT's superior spatial and contrast resolution, reduced radiation dose, and…

Advances in quantum technologies are accelerating the demand for optical quantum state sensors that combine high precision, versatility, and scalability within a unified hardware platform. Quantum reservoir computing offers a powerful route…

Modern problems in high-performance computing, ranging from training and inferencing deep learning models in computer vision and language models to simulating complex physical systems with nonlinearly-coupled equations, require exponential…

Particle physics simulations are the cornerstone of nuclear engineering applications. Among them radiotherapy (RT) is crucial for society, with 50% of cancer patients receiving radiation treatments. For the most precise targeting of tumors,…

机器学习 · 计算机科学 2021-09-10 Oscar Pastor-Serrano , Zoltán Perkó

Photonics is the platform of choice to build a modular, easy-to-network quantum computer operating at room temperature. However, no concrete architecture has been presented so far that exploits both the advantages of qubits encoded into…

Long-lived electronic coherences in various photosynthetic complexes at cryogenic and room temperature have generated vigorous efforts both in theory and experiment to understand their origins and explore their potential role to biological…

量子物理 · 物理学 2010-12-16 Patrick Rebentrost , Sangwoo Shim , Joel Yuen-Zhou , Alán Aspuru-Guzik

Photonic quantum computing is one of the leading approaches to universal quantum computation. However, large-scale implementation of photonic quantum computing has been hindered by its intrinsic difficulties, such as probabilistic…

量子物理 · 物理学 2019-06-17 Shuntaro Takeda , Akira Furusawa

We summarize recent results and ongoing activities in mathematical algorithms and computer science methods related to proton computed tomography (pCT) and intensity-modulated particle therapy (IMPT) treatment planning. Proton therapy…

医学物理 · 物理学 2021-08-24 Yair Censor , Keith E. Schubert , Reinhard W. Schulte

We propose a probabilistic quantum algorithm that decides whether a monochrome picture matches a given template (or one out of a set of templates). As a major advantage to classical pattern recognition, the algorithm just requires a few…

量子物理 · 物理学 2008-08-28 Gernot Schaller , Ralf Schützhold

Oncolytic viral therapy (OVT) is an emerging precision therapy for aggressive and recurrent cancers. However, its clinical efficacy is hindered by the complexity of tumor-virus-immune interactions and the lack of predictive models for…

定量方法 · 定量生物学 2026-03-11 Abicumaran Uthamacumaran , Juri Kiyokawa , Hiroaki Wakimoto

We propose a hybrid quantum-classical approximate optimization algorithm for photonic quantum computing, specifically tailored for addressing continuous-variable optimization problems. Inspired by counterdiabatic protocols, our algorithm…

量子物理 · 物理学 2024-10-03 Pranav Chandarana , Koushik Paul , Mikel Garcia-de-Andoin , Yue Ban , Mikel Sanz , Xi Chen

Background: Promising results for mammary carcinoma treatment with photodynamic therapy (PDT) presuppose a careful selection of irradiation light wavelength. Methods: 4T1 tumors implanted in NOD-SCID mice were treated with Metvix-PDT under…

We propose a novel architecture for fault-tolerant quantum computing that incorporates strong single-photon nonlinearities into a photonic GHZ-measurement-based architecture. The nonlinearities substantially reduce resource overheads…

量子物理 · 物理学 2025-10-09 Maike Ostmann , Joshua Nunn , Alex E. Jones

A variety of complicated computational scenarios have made unprecedented demands on the computing power and energy efficiency of electronic computing systems, including solving intractable nondeterministic polynomial-time (NP)-complete…

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