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Amperometry is a commonly used electrochemical method for studying the process of exocytosis in real-time. Given the high precision of recording that amperometry procedures offer, the volume of data generated can span over several hundreds…

亚细胞过程 · 定量生物学 2023-02-07 Jeyashree Krishnan , Zeyu Lian , Pieter E. Oomen , Xiulan He , Soodabeh Majdi , Andreas Schuppert , Andrew Ewing

A fully automated linear scanning attenuated total reflection (ATR) accessory is presented for Fourier transform infrared (FTIR) spectroscopy. The approach is based on the accurate displacement of a multi-bounce ATR crystal relative to a…

Objective: To develop an accurate myocardial T1 mapping technique at 5T using Look-Locker-based multiple inversion-recovery with the real-time spoiled gradient echo (GRE) acquisition. Approach: The proposed T1 mapping technique (mIR-rt)…

We study the possibility to use the Cherenkov light for the efficient detection of 511 keV photons with the goal to use it in TOF-PET. We designed and tested two detection modules consisting of PbF$_2$ crystals attached to Planacon MCP-PMT…

仪器与探测器 · 物理学 2020-03-24 C. Canot , M. Alokhina , P. Abbon , J. P. Bard , D. Breton , E. Delagnes , J. Maalmi , G. Tauzin , D. Yvon , V. Sharyy

This study explores the correlation between iron mass on cell surfaces and the resultant magnetic field. Human colorectal cancer cells (HT29 line) were labeled with varying concentrations of SPIONs and imaged via a NV center widefield…

Magnetic particle imaging (MPI) is a rapidly developing medical imaging modality that exploits the non-linear response of magnetic nanoparticles (MNPs). Color MPI widens the functionality of MPI, empowering it with the capability to…

信号处理 · 电气工程与系统科学 2021-12-10 M. Tunç Arslan , A. Alper Özaslan , Semih Kurt , Yavuz Muslu , Emine Ulku Saritas

We demonstrate a wide-band all-optical method of nanoscale magnetic resonance (MR) spectroscopy under ambient conditions. Our method relies on cross-relaxation between a probe spin, the electronic spin of a nitrogen-vacancy centre in…

Super-resolution mapping of the 3D orientation of fluorophores reveals the alignment of biological structures where the fluorophores are tightly attached, and thus plays a vital role in studying the organization and dynamics of…

光学 · 物理学 2024-01-23 Xiaowei Liu , Mingwei Tang , Ning Zhou , Chenlei Pang , Zhong Wen , Xu Liu , Qing Yang

Signal-to-noise ratio optimization, regarding repetition time selection, was explored mathematically and experimentally for single-voxel proton magnetic resonance spectroscopy. Theoretical findings were benchmarked against phantom…

We looked for a biological analogy to developed an improved surface coil to acquire magnetic resonance images. Nature offers engineering solutions that can be exploited to improve the performance of devices, such as MRI RF coils. In this…

A recently introduced quantitative susceptibility mapping (QSM) technique, $\chi$-separation, offers the capability to separate paramagnetic ($\chi_{\text{para}}$) and diamagnetic ($\chi_{\text{dia}}$) susceptibility distribution within the…

In positron emission tomography (PET), it is indispensable to perform attenuation correction in order to obtain the quantitatively accurate activity map (tracer distribution) in the body. Generally, this is carried out based on the…

医学物理 · 物理学 2025-10-16 Liyang Hu , Chong Chen

Owing to the invasiveness and low accuracy of other tests, including biopsy and ferritin levels, magnetic resonance imaging (T2 and T2*-MRI) has been considered the standard test for patients with thalassemia (THM). Regarding deep learning…

图像与视频处理 · 电气工程与系统科学 2023-05-18 Iraj Abedi , Maryam Zamanian , Hamidreza Bolhasani , Milad Jalilian

Hyperion-IID is a positron emission tomography (PET) insert which allows simultaneous operation in a clinical magnetic resonance imaging (MRI) scanner. To read out the scintillation light of the employed LYSO crystal arrays with a pitch of…

Background: Accurate myocardial T1 mapping at 5T remains a technical challenge due to field inhomogeneity and prolonged T1 values. The aim of this study is to develop an accurate and clinically applicable myocardial T1 mapping technique for…

Inhomogeneity of the transmitted radiofrequency field B1+ is a major factor hindering the image quality in Magnetic Resonance Imaging (MRI) at high field strengths. Here, a novel approach is presented, to locally modulate the B1+ utilizing…

A model-based reconstruction technique for accelerated T2 mapping with improved accuracy is proposed using undersampled Cartesian spin-echo MRI data. The technique employs an advanced signal model for T2 relaxation that accounts for…

医学物理 · 物理学 2015-03-03 Tilman J. Sumpf , Andreas Petrovic , Martin Uecker , Florian Knoll , Jens Frahm

Whole-brain proton magnetic resonance spectroscopic imaging (1H-MRSI) is a non-invasive technique for assessing neurochemical distribution in the brain, offering valuable insights into brain functions and neural diseases. It greatly…

医学物理 · 物理学 2024-10-08 Zhiwei Huang , Uzay Emir , Andre Doring , Antoine Klauser , Ying Xiao , Mark Widmaier , Lijing Xin

Waveguides have been successfully used to generate magnetic resonance images at 7 T with whole-body systems. The bore limits the magnetic resonance signal transmitted because its specific cut-off frequency is greater than the majority of…

医学物理 · 物理学 2015-06-12 F. Vazquez , R. Martin , O. Marrufo , A. O. Rodriguez

This work addresses the problem of estimating proton density and T1 maps from two partially sampled K-space scans such that the total acquisition time remains approximately the same as a single scan. Existing multi parametric non linear…

计算机视觉与模式识别 · 计算机科学 2015-12-25 Anupriya Gogna , Angshul Majumdar