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Dementia, a prevalent neurodegenerative condition, is a major manifestation of Alzheimer's disease (AD). As the condition progresses from mild to severe, it significantly impairs the individual's ability to perform daily tasks…

机器学习 · 计算机科学 2023-11-06 Md Gulzar Hussain , Ye Shiren

Recent technology and equipment advancements provide with us opportunities to better analyze Alzheimer's disease (AD), where we could collect and employ the data from different image and genetic modalities that may potentially enhance the…

机器学习 · 计算机科学 2023-03-09 Kai Liu , Yarui Cao

Generative AI framework-based modeling and prediction of longitudinal human brain images offer an efficient mechanism to track neurodegenerative progression, essential for the assessment of diseases like Alzheimer's. Among the existing…

计算机视觉与模式识别 · 计算机科学 2026-03-03 Ayantika Das , Keerthi Ram , Mohanasankar Sivaprakasam

Alzheimer's disease is a progressive, neurodegenerative disorder that causes memory loss and cognitive decline. While there has been extensive research in applying deep learning models to Alzheimer's prediction tasks, these models remain…

计算机视觉与模式识别 · 计算机科学 2025-09-15 Emily Kaczmarek , Justin Szeto , Brennan Nichyporuk , Tal Arbel

Alzheimer's disease is one of the most common types of neurodegenerative disease, characterized by the accumulation of amyloid-beta plaque and tau tangles. Recently, deep learning approaches have shown promise in Alzheimer's disease…

图像与视频处理 · 电气工程与系统科学 2024-07-03 Gia Minh Hoang , Youngjoo Lee , Jae Gwan Kim

Alzheimer's disease (AD) is a neurodegenerative disorder with no known cure that affects tens of millions of people worldwide. Early detection of AD is critical for timely intervention to halt or slow the progression of the disease. In this…

机器学习 · 计算机科学 2025-07-08 Mahdi Moghaddami , Clayton Schubring , Mohammad-Reza Siadat

United States healthcare systems are struggling to meet the growing demand for neurological care, particularly in Alzheimer's disease and related dementias (ADRD). Generative AI built on language models (LLMs) now enables agentic AI systems…

Alzheimer's disease (AD) is a prevalent and debilitating neurodegenerative disorder impacting a large aging population. Detecting AD in all its presymptomatic and symptomatic stages is crucial for early intervention and treatment. An active…

计算机视觉与模式识别 · 计算机科学 2023-10-31 Yasmine Mustafa , Tie Luo

Reliability in Neural Networks (NNs) is crucial in safety-critical applications like healthcare, and uncertainty estimation is a widely researched method to highlight the confidence of NNs in deployment. In this work, we propose an…

机器学习 · 计算机科学 2020-11-20 Utkarsh Sarawgi , Wazeer Zulfikar , Rishab Khincha , Pattie Maes

Reinforcement learning (RL) has recently shown promise in predicting Alzheimer's disease (AD) progression due to its unique ability to model domain knowledge. However, it is not clear which RL algorithms are well-suited for this task.…

Alzheimer's disease (AD) is a neurodegenerative disorder affecting millions worldwide, necessitating early and accurate diagnosis for optimal patient management. In recent years, advancements in deep learning have shown remarkable potential…

Alzheimer's Disease (AD) is characterized by a cascade of biomarkers becoming abnormal, the pathophysiology of which is very complex and largely unknown. Event-based modeling (EBM) is a data-driven technique to estimate the sequence in…

机器学习 · 计算机科学 2019-08-14 Vikram Venkatraghavan , Esther E. Bron , Wiro J. Niessen , Stefan Klein

Alzheimer's Disease (AD) is a neurodegenerative disease that affects subjects in a broad range of severity and is assessed in clinical trials with multiple cognitive and functional instruments. As clinical trials in AD increasingly focus on…

Computer-aided early diagnosis of Alzheimers Disease (AD) and its prodromal form, Mild Cognitive Impairment (MCI), has been the subject of extensive research in recent years. Some recent studies have shown promising results in the AD and…

计算机视觉与模式识别 · 计算机科学 2018-01-19 Alexander Khvostikov , Karim Aderghal , Jenny Benois-Pineau , Andrey Krylov , Gwenaelle Catheline

We propose a machine-learning approach to model long-term out-of-sample dynamics of brain activity from task-dependent fMRI data. Our approach is a three stage one. First, we exploit Diffusion maps (DMs) to discover a set of variables that…

数值分析 · 数学 2024-11-05 Ioannis K. Gallos , Daniel Lehmberg , Felix Dietrich , Constantinos Siettos

Introduction: It is challenging at baseline to predict when and which individuals who meet criteria for mild cognitive impairment (MCI) will ultimately progress to Alzheimer's disease (AD) dementia. Methods: A deep learning method is…

计算机视觉与模式识别 · 计算机科学 2019-04-17 Hongming Li , Mohamad Habes , David A. Wolk , Yong Fan

Brain imaging has allowed neuroscientists to analyze brain morphology in genetic and neurodevelopmental disorders, such as Down syndrome, pinpointing regions of interest to unravel the neuroanatomical underpinnings of cognitive impairment…

计算机视觉与模式识别 · 计算机科学 2024-09-23 Jordi Malé , Juan Fortea , Mateus Rozalem Aranha , Yann Heuzé , Neus Martínez-Abadías , Xavier Sevillano

Reliable detection of the prodromal stages of Alzheimer's disease (AD) remains difficult even today because, unlike other neurocognitive impairments, there is no definitive diagnosis of AD in vivo. In this context, existing research has…

机器学习 · 计算机科学 2021-08-03 Amish Mittal , Sourav Sahoo , Arnhav Datar , Juned Kadiwala , Hrithwik Shalu , Jimson Mathew

Alzheimer's disease (AD) is a neuro-degenerative disease that can cause dementia and result severe reduction in brain function inhibiting simple tasks especially if no preventative care is taken. Over 1 in 9 Americans suffer from AD induced…

图像与视频处理 · 电气工程与系统科学 2023-06-21 Paul K. Mandal , Rakesh Mahto

Grade prediction for future courses not yet taken by students is important as it can help them and their advisers during the process of course selection as well as for designing personalized degree plans and modifying them based on their…

机器学习 · 计算机科学 2020-03-12 Sara Morsy , George Karypis