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Generative approaches for cross-modality transformation have recently gained significant attention in neuroimaging. While most previous work has focused on case-control data, the application of generative models to disorder-specific…

神经元与认知 · 定量生物学 2024-05-10 Reihaneh Hassanzadeh , Anees Abrol , Hamid Reza Hassanzadeh , Vince D. Calhoun

Given the complexity of genetic risk prediction, there is a critical need for the development of novel methodologies that can effectively capture intricate genotype--phenotype relationships (e.g., nonlinear) while remaining statistically…

应用统计 · 统计学 2025-10-03 Heng Ge , Qing Lu

Early and accurate detection of Alzheimer's disease (AD) remains a major challenge in medical diagnosis due to its subtle onset and progressive nature. This research introduces an explainable ensemble learning Framework designed to classify…

机器学习 · 计算机科学 2026-03-06 Nishan Mitra

Alzheimer's Disease (AD) is a progressive neurodegenerative disorder that leads to dementia, and early intervention can greatly benefit from analyzing linguistic abnormalities. In this work, we explore the potential of Large Language Models…

计算与语言 · 计算机科学 2025-12-23 Chuyuan Li , Raymond Li , Thalia S. Field , Giuseppe Carenini

The discovery of linear embedding is the key to the synthesis of linear control techniques for nonlinear systems. In recent years, while Koopman operator theory has become a prominent approach for learning these linear embeddings through…

机器人学 · 计算机科学 2026-03-02 Rajpal Singh , Chandan Kumar Sah , Jishnu Keshavan

Alzheimer's disease is a progressive neurological disorder characterized by cognitive impairment and memory loss. With the increasing aging population, the incidence of AD is continuously rising, making early diagnosis and intervention an…

图像与视频处理 · 电气工程与系统科学 2023-11-23 Guian Fang , Mengsha Liu , Yi Zhong , Zhuolin Zhang , Jiehui Huang , Zhenchao Tang , Calvin Yu-Chian Chen

Nonlinear differential equations are encountered as models of fluid flow, spiking neurons, and many other systems of interest in the real world. Common features of these systems are that their behaviors are difficult to describe exactly and…

系统与控制 · 电气工程与系统科学 2024-09-17 Zexin Sun , Mingyu Chen , John Baillieul

Alzheimer's disease (AD), characterized by progressive cognitive decline and memory loss, presents a formidable global health challenge, underscoring the critical importance of early and precise diagnosis for timely interventions and…

图像与视频处理 · 电气工程与系统科学 2024-10-01 Arindam Majee , Avisek Gupta , Sourav Raha , Swagatam Das

Deep learning (DL) for predicting Alzheimer's disease (AD) has provided timely intervention in disease progression yet still demands attentive interpretability to explain how their DL models make definitive decisions. Recently,…

人工智能 · 计算机科学 2023-10-06 Kwanseok Oh , Da-Woon Heo , Ahmad Wisnu Mulyadi , Wonsik Jung , Eunsong Kang , Kun Ho Lee , Heung-Il Suk

Neurodegeneration as measured through magnetic resonance imaging (MRI) is recognized as a potential biomarker for diagnosing Alzheimer's disease (AD), but is generally considered less specific than amyloid or tau based biomarkers. Due to a…

计算机视觉与模式识别 · 计算机科学 2024-08-06 Rosemary He , Gabriella Ang , Daniel Tward

Quantum computation offers potential exponential speedups for simulating certain physical systems, but its application to nonlinear dynamics is inherently constrained by the requirement of unitary evolution. We propose the quantum Koopman…

量子物理 · 物理学 2025-07-30 Baoyang Zhang , Zhen Lu , Yaomin Zhao , Yue Yang

Early and accurate diagnosis of Alzheimer Disease is critical for effective clinical intervention, particularly in distinguishing it from Mild Cognitive Impairment, a prodromal stage marked by subtle structural changes. In this study, we…

图像与视频处理 · 电气工程与系统科学 2025-10-08 Fahad Mostafa , Kannon Hossain , Hafiz Khan

Objective: We aimed to develop and validate a novel multimodal framework HiMAL (Hierarchical, Multi-task Auxiliary Learning) framework, for predicting cognitive composite functions as auxiliary tasks that estimate the longitudinal risk of…

机器学习 · 计算机科学 2026-02-06 Sayantan Kumar , Sean Yu , Andrew Michelson , Thomas Kannampallil , Philip Payne

We propose a novel perspective of the attention mechanism by reinventing it as a memory architecture for neural networks, namely Neural Attention Memory (NAM). NAM is a memory structure that is both readable and writable via differentiable…

机器学习 · 计算机科学 2023-10-17 Hyoungwook Nam , Seung Byum Seo

Recent advancements in large language models (LLMs) have achieved promising performances across various applications. Nonetheless, the ongoing challenge of integrating long-tail knowledge continues to impede the seamless adoption of LLMs in…

Early diagnosis of Alzheimer Diagnostics (AD) is a challenging task due to its subtle and complex clinical symptoms. Deep learning-assisted medical diagnosis using image recognition techniques has become an important research topic in this…

图像与视频处理 · 电气工程与系统科学 2024-01-26 Yihao Lin , Ximeng Li , Yan Zhang , Jinshan Tang

In this work, we propose three explainable deep learning architectures to automatically detect patients with Alzheimer`s disease based on their language abilities. The architectures use: (1) only the part-of-speech features; (2) only…

计算与语言 · 计算机科学 2021-01-11 Ning Wang , Mingxuan Chen , K. P. Subbalakshmi

Cross-modal fusion of different types of neuroimaging data has shown great promise for predicting the progression of Alzheimer's Disease(AD). However, most existing methods applied in neuroimaging can not efficiently fuse the functional and…

图像与视频处理 · 电气工程与系统科学 2022-07-15 Junren Pan , Shuqiang Wang

In recent years, deep learning models have been applied to neuroimaging data for early diagnosis of Alzheimer's disease (AD). Structural magnetic resonance imaging (sMRI) and positron emission tomography (PET) images provide structural and…

图像与视频处理 · 电气工程与系统科学 2023-08-01 Yanteng Zhanga , Xiaohai He , Yi Hao Chan , Qizhi Teng , Jagath C. Rajapakse