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The differential diagnosis of neurodegenerative dementias is a challenging clinical task, mainly because of the overlap in symptom presentation and the similarity of patterns observed in structural neuroimaging. To improve diagnostic…

机器学习 · 计算机科学 2025-05-27 Andrew Zamai , Nathanael Fijalkow , Boris Mansencal , Laurent Simon , Eloi Navet , Pierrick Coupe

The integration of artificial intelligence (AI) in medical diagnostics represents a significant advancement in managing upper gastrointestinal (GI) cancer, a major cause of global cancer mortality. Specifically for gastric cancer (GC),…

Machine learning has been increasingly used to obtain individualized neuroimaging signatures for disease diagnosis, prognosis, and response to treatment in neuropsychiatric and neurodegenerative disorders. Therefore, it has contributed to a…

Recent advancements in deep learning have significantly revolutionized the field of clinical diagnosis and treatment, offering novel approaches to improve diagnostic precision and treatment efficacy across diverse clinical domains, thus…

Musculoskeletal disorders represent a leading cause of global disability, creating an urgent demand for precise interpretation of medical imaging. Current artificial intelligence (AI) approaches in orthopedics predominantly rely on…

计算机视觉与模式识别 · 计算机科学 2026-01-27 Kang Yu , Dingyu Wang , Zimu Yuan , Nan Zhou , Jiajun Liu , Jiaxin Liu , Shanggui Liu , Yaoyan Zheng , Huishu Yuan , Di Huang , Dong Jiang

Foundation models (FMs) are large-scale deep learning models trained on massive datasets, often using self-supervised learning techniques. These models serve as a versatile base for a wide range of downstream tasks, including those in…

机器学习 · 计算机科学 2025-01-17 Wasif Khan , Seowung Leem , Kyle B. See , Joshua K. Wong , Shaoting Zhang , Ruogu Fang

Advances in foundation modeling have reshaped computational pathology. However, the increasing number of available models and lack of standardized benchmarks make it increasingly complex to assess their strengths, limitations, and potential…

计算机视觉与模式识别 · 计算机科学 2025-02-11 Andrew Zhang , Guillaume Jaume , Anurag Vaidya , Tong Ding , Faisal Mahmood

Foundation model, which is pre-trained on broad data and is able to adapt to a wide range of tasks, is advancing healthcare. It promotes the development of healthcare artificial intelligence (AI) models, breaking the contradiction between…

计算机与社会 · 计算机科学 2024-04-05 Yuting He , Fuxiang Huang , Xinrui Jiang , Yuxiang Nie , Minghao Wang , Jiguang Wang , Hao Chen

Foundation models in artificial intelligence (AI) are transforming medical imaging by enabling general-purpose feature learning from large-scale, unlabeled datasets. In this work, we introduce BrainFound, a self-supervised foundation model…

计算机视觉与模式识别 · 计算机科学 2026-01-01 Moona Mazher , Geoff J. M. Parker , Daniel C. Alexander

Recent advances in deep learning have completely transformed the domain of computational pathology (CPath). More specifically, it has altered the diagnostic workflow of pathologists by integrating foundation models (FMs) and vision-language…

机器学习 · 计算机科学 2024-09-19 Dibaloke Chanda , Milan Aryal , Nasim Yahya Soltani , Masoud Ganji

Pathology foundation models (PFMs) have emerged as a core approach for learning transferable representations from whole slide images (WSIs), and they are typically benchmarked through downstream clinical endpoints. While such task level…

计算机视觉与模式识别 · 计算机科学 2026-05-26 Bokai Zhao , Yiyang Zhang , Yuanchi Zhu , Hanqing Chao , Long Bai , Tai Ma , Minfeng Xu , Ming Song , Tianzi Jiang

While the prevalence of Autism Spectrum Disorder (ASD) is increasing, research continues in an effort to identify common etiological and pathophysiological bases. In this regard, modern machine learning and network science pave the way for…

图像与视频处理 · 电气工程与系统科学 2020-08-06 Sarah Itani , Dorina Thanou

Alzheimer's disease (AD), the predominant form of dementia, is a growing global challenge, emphasizing the urgent need for accurate and early diagnosis. Current clinical diagnoses rely on radiologist expert interpretation, which is prone to…

图像与视频处理 · 电气工程与系统科学 2024-07-12 Simisola Odimayo , Chollette C. Olisah , Khadija Mohammed

Progressive neurodegenerative diseases, including Alzheimer's disease (AD), multiple sclerosis (MS), Parkinson's disease (PD), and amyotrophic lateral sclerosis (ALS), exhibit complex, nonlinear trajectories that challenge deterministic…

其他定量生物学 · 定量生物学 2025-08-12 John D. Mayfield

Head computed tomography (CT) imaging is a widely-used imaging modality with multitudes of medical indications, particularly in assessing pathology of the brain, skull, and cerebrovascular system. It is commonly the first-line imaging in…

Recent advancements in AI and medical imaging offer transformative potential in emergency head CT interpretation for reducing assessment times and improving accuracy in the face of an increasing request of such scans and a global shortage…

Current neuroimaging techniques provide paths to investigate the structure and function of the brain in vivo and have made great advances in understanding Alzheimer's disease (AD). However, the group-level analyses prevalently used for…

定量方法 · 定量生物学 2021-05-31 Nanyan Zhu , Chen Liu , Xinyang Feng , Dipika Sikka , Sabrina Gjerswold-Selleck , Scott A. Small , Jia Guo

Foundation models have substantially advanced computational pathology by learning transferable visual representations from large histological datasets, yet their performance varies widely across tasks due to differences in training data…

计算机视觉与模式识别 · 计算机科学 2026-02-16 Wenhui Lei , Yusheng Tan , Anqi Li , Hanyu Chen , Hengrui Tian , Ruiying Li , Zhengqun Jiang , Fang Yan , Xiaofan Zhang , Shaoting Zhang

Functional MRI (fMRI) is crucial for studying brain function and diagnosing neurological disorders. However, existing analysis methods suffer from reproducibility and transferability challenges due to complex preprocessing pipelines and…

Neuro-oncology poses unique challenges for machine learning due to heterogeneous data and tumor complexity, limiting the ability of foundation models (FMs) to generalize across cohorts. Existing FMs also perform poorly in predicting…

计算机视觉与模式识别 · 计算机科学 2025-09-22 Moinak Bhattacharya , Angelica P. Kurtz , Fabio M. Iwamoto , Prateek Prasanna , Gagandeep Singh