相关论文: A Versatile Optical Frontend for Multicolor Fluore…
Lab-on-a-Chip (LoC) devices combining microfluidic analyte provision with integrated optical analysis are highly desirable for several applications in biological oder medical sciences. While the microfluidic approach is already broadly…
Optical systems with wide field-of-views (FOV) are crucial for many applications such as high performance imaging, optical projection, augmented/virtual reality, and miniaturized medical imaging tools. Typically, aberration-free imaging…
In optical imaging, achieving high resolution often comes at the expense of a shallow depth of field. This means that when using a standard microscope, any minor movement of the object along the optical axis can cause the image to become…
Confocal Raman microscopy, a highly specific and label-free technique for the microscale study of thick samples, often presents difficulties due to weak Raman signals. Inhomogeneous samples introduce wavefront aberrations that further…
Integrating conventional optics into compact nanostructured surfaces is the goal of flat optics. Despite the enormous progress of this technology, there are still critical challenges for real world applications due to a limited efficiency…
Imaging techniques such as functional near-infrared spectroscopy (fNIRS) and diffuse optical tomography (DOT) achieve deep, non-invasive sensing in turbid media, but they are constrained by the photon budget. Wavefront shaping (WFS) can…
Plastic nanoparticles present technological opportunities and environmental concerns, but measurement challenges impede product development and hazard assessment. To meet these challenges, we advance a lateral nanoflow assay that integrates…
Wide-field lensfree on-chip microscopy, which leverages holography principles to capture interferometric light-field encodings without lenses, is an emerging imaging modality with widespread interest given the large field-of-view compared…
On-invasive optical imaging techniques are essential diagnostic tools in many fields. Although various recent methods have been proposed to utilize and control light in multiple scattering media, non-invasive optical imaging through and…
Freeform optical components offer significant compactization of multi-lens systems, as well as advanced manipulation of light that is not possible with traditional systems. However, their fabrication relies on machining processes that are…
Correlative microscopy is a powerful technique that combines the advantages of multiple imaging modalities to achieve a comprehensive understanding of investigated samples. For example, fluorescence microscopy provides unique functional…
The power-balanced hybrid optical imaging system is a special design of a diffractive computational camera, introduced in this paper, with image formation by a refractive lens and Multilevel Phase Mask (MPM). This system provides a long…
Fluorescence detection, either involving propagating or near-field emission, is widely being used in spectroscopy, sensing and microscopy. Total internal reflection fluorescence (TIRF) confines fluorescence excitation by an evanescent…
The numerical aperture (NA) of a lens determines its ability to focus light and its resolving capability. Having a large NA is a very desirable quality for applications requiring small light-matter interaction volumes or large angular…
Adaptive optics enables the deployment of interferometer-based spectroscopy without the need for moving parts necessary for scanning the interferometer arms. Here, we employ a Michelson Interferometer in conjunction with a Spatial Light…
Optical nanofibers (ONF) of subwavelength dimensions confine light in modes with a strong evanescent field that can trap, probe, and manipulate nearby quantum systems. To measure the evanescent field and propagating modes, and to optimize…
Flat optics consisting of nanostructures of high-refractive-index materials produce lenses with thin form factors that tend to operate only at specific wavelengths. Recent attempts to achieve achromatic lenses uncover a trade-off between…
Miniaturized photodetectors are becoming increasingly sought-after components for a range of next generation technologies, such as autonomous vehicles, integrated wearable devices, or gadgets embedded in the Internet of Things. A major…
High-numerical-aperture (NA) oblique plane microscopy enables noninvasive fluorescence imaging of subcellular dynamics without requiring radical sample modification. However, performance degrades at depth in multicellular specimens as…
Optical Fourier surfaces (OFSs), featuring sinusoidally profiled diffractive elements, manipulate light through patterned nanostructures and incident angle modulation. Compared to altering structural parameters, tuning elevation and azimuth…