相关论文: A Versatile Optical Frontend for Multicolor Fluore…
Based on grating diffraction principle, optical fiber transmission principle and optical interference principle, a multi-functional portable optical measuring instrument is constructed in this paper. The optical measurement visualization…
Fundus photography is indispensable for clinical detection and management of eye diseases. Limited image contrast and field of view (FOV) are common limitations of conventional fundus cameras, making it difficult to detect subtle…
The flexible endoscope is a minimally invasive tool in clinical settings, but most of them rely on exogenous staining for diagnosis to provide qualitative information. Here, we demonstrated a flexible endoscopic microscopy (FEM) with…
Three-dimensional elements, with refractive index distribution structured at sub-wavelength scale, provide an expansive optical design space that can be harnessed for demonstrating multi-functional free-space optical devices. Here we…
On-chip optical neural networks (ONNs) have recently emerged as an attractive hardware accelerator for deep learning applications, characterized by high computing density, low latency, and compact size. As these networks rely heavily on…
We proposed a Smartphone-based Optical Sectioning (SOS) microscope based on the HiLo technique, with a single smartphone replacing a high-cost illumination source and a camera sensor.We built our SOS with off-the-shelf optical mechanical…
We report on the development of a compact (volume $\approx$ 100\:cm$^3$), multimode diffraction-limited Raman spectrograph and probe designed to be compact as possible. The spectrograph uses `off the shelf' optics, a custom 3D-printed…
Traditional optical imaging faces an unavoidable trade-off between resolution and depth of field (DOF). To increase resolution, high numerical apertures (NA) are needed, but the associated large angular uncertainty results in a limited…
We demonstrate in vivo endoscopic optical coherence tomography (OCT) imaging in the forward direction using a flexible fiber bundle. In comparison to current conventional forward looking probe schemes, our approach simplifies the endoscope…
Nonlinear photonic chips have succeeded in generating and processing signals all-optically with performance far superior to that possible electronically - particularly with respect to speed. Although silicon-on-insulator has been the…
We have designed, built, and characterized a high-resolution objective lens that is compatible with an ultra-high vacuum environment. The lens system exploits the principle of the Weierstrass-sphere solid immersion lens to reach a numerical…
In optical anti-counterfeiting, several distinct optically variable devices (OVDs) are often concurrently employed to compensate for the insufficient security level of constituent OVDs. Alternatively, metasurfaces that exhibit multiple…
A miniaturized full-frequency encoded illumination (mini-FEI) chip is presented for high-throughput super-resolution imaging using the spatial frequency shift (SFS) effect. A tunable full SFS scheme is achieved through propagating and…
Optical fiber-based platforms are increasingly explored as compact, minimally invasive tools for integrated photonic functionalities in biomedical applications. Among these, the combination of plasmonic heating and optical sensing on a…
Future large space telescopes will be equipped with adaptive optics (AO) to overcome wavefront aberrations and achieve high contrast for imaging faint astronomical objects, such as earth-like exoplanets and debris disks. In contrast to AO…
We describe the effect of optical aberrations on fluorescence fluctuations microscopy (FFM), when focusing through a single living cell. FFM measurements are performed in an aqueous fluorescent solution and prove to be a highly sensitive…
The tolerance analysis of freeform surfaces plays a crucial role in the development of advanced imaging systems. However, the intricate relationship between surface error and imaging quality poses significant challenges, necessitating dense…
Many uses of lasers place the highest importance on access to specific wavelength bands. For example, mobilizing optical-atomic clocks for a leap in sensing requires compact lasers at frequencies spread across the visible and near infrared.…
We report on the recently emerging (Laser) Light Sheet based Fluorescence Microscopy field (LSFM). The techniques used in this field allow to study and visualize biomedical objects non-destructively in high-resolution through virtual…
We theoretically and experimentally demonstrate a multifrequency excitation and detection scheme in apertureless near field optical microscopy, that exceeds current state of the art sensitivity and background suppression. By exciting the…