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Efficient testing and vaccination protocols are critical aspects of epidemic management. To study the optimal allocation of limited testing and vaccination resources in a heterogeneous contact network of interacting susceptible, recovered,…

种群与进化 · 定量生物学 2026-05-12 Mingtao Xia , Lucas Böttcher , Tom Chou

During various stages of the COVID-19 pandemic, countries implemented diverse vaccine management approaches, influenced by variations in infrastructure and socio-economic conditions. This article provides a comprehensive overview of…

最优化与控制 · 数学 2024-05-27 Shibshankar Dey , Ali Kaan Kurbanzade , Esma S. Gel , Joseph Mihaljevic , Sanjay Mehrotra

Since early 2020, the world has been dealing with a raging pandemic outbreak: COVID-19. A year later, vaccines have become accessible, but in limited quantities, so that governments needed to devise a strategy to decide which part of the…

种群与进化 · 定量生物学 2022-04-13 Sander Tonkens , Paul de Klaver , Mauro Salazar

National responses to the Covid-19 pandemic varied markedly across countries, from business-as-usual to complete shutdowns. Policies aimed at disrupting the viral transmission cycle and preventing the healthcare system from being…

种群与进化 · 定量生物学 2021-10-27 Arash Saeidpour , Pejman Rohani

To mitigate the impact of the pandemic, several measures include lockdowns, rapid vaccination programs, school closures, and economic stimulus. These interventions can have positive or unintended negative consequences. Current research to…

机器学习 · 计算机科学 2025-08-11 Gaurav Deshkar , Jayanta Kshirsagar , Harshal Hayatnagarkar , Janani Venugopalan

This study explores the vaccine prioritization strategy to reduce the overall burden of the pandemic when the supply is limited. Existing methods conduct macro-level or simplified micro-level vaccine distribution by assuming the homogeneous…

种群与进化 · 定量生物学 2023-05-10 Lu Ling , Washim Uddin Mondal , Satish V , Ukkusuri

Recent Covid-19 pandemic has demonstrated the need of efficient epidemic outbreak management. We study the optimal control problem of minimizing the fraction of infected population by applying vaccination and treatment control strategies,…

社会与信息网络 · 计算机科学 2021-12-07 Jagtap Kalyani Devendra , Kundan Kandhway

We propose a mathematical framework, based on conic geometric programming, to control a susceptible-infected-susceptible viral spreading process taking place in a directed contact network with unknown contact rates. We assume that we have…

最优化与控制 · 数学 2014-12-09 Shuo Han , Victor M. Preciado , Cameron Nowzari , George J. Pappas

Modelling epidemics via classical population-based models suffers from shortcomings that so-called individual-based models are able to overcome, as they are able to take heterogeneity features into account, such as super-spreaders, and…

最优化与控制 · 数学 2022-05-16 C. Courtès , E. Franck , K. Lutz , L. Navoret , Y. Privat

During the Covid-19 pandemic a key role is played by vaccination to combat the virus. There are many possible policies for prioritizing vaccines, and different criteria for optimization: minimize death, time to herd immunity, functioning of…

Network-based interventions against epidemic spread are most powerful when the full network structure is known. However, in practice, resource constraints require decisions to be made based on partial network information. We investigated…

应用统计 · 统计学 2019-03-19 Yingrui Yang , Ashley McKhann , Sixing Chen , Guy Harling , Jukka-Pekka Onnela

This article considers the minimization of the total number of infected individuals over the course of an epidemic in which the rate of infectious contacts can be reduced by time-dependent nonpharmaceutical interventions. The societal and…

最优化与控制 · 数学 2023-03-16 Tom Britton , Lasse Leskelä

Vaccinations against viruses have always been the need of the hour since long past. However, it is hard to efficiently distribute the vaccines (on time) to all the corners of a country, especially during a pandemic. Considering the vastness…

机器学习 · 计算机科学 2022-08-03 Jayeeta Mondal , Jeet Dutta , Hrishav Bakul Barua

The problem of targeted network immunization can be defined as the one of finding a subset of nodes in a network to immunize or vaccinate in order to minimize a tradeoff between the cost of vaccination and the final (stationary) expected…

物理与社会 · 物理学 2015-07-10 F. Altarelli , A. Braunstein , L. Dall'Asta , J. R. Wakeling , R. Zecchina

Since the recent introduction of several viable vaccines for SARS-CoV-2, vaccination uptake has become the key factor that will determine our success in containing the COVID-19 pandemic. We argue that game theory and social network models…

In this research, we develop a framework to analyze the interaction between the economy and the Covid-19 pandemic using an extension of SIR epidemic model. At the outset, we assume there are two health related investments including general…

最优化与控制 · 数学 2022-02-14 Zachariah Sinkala , Vajira Manathunga , Bichaka Fayissa

We develop a model of infection spread that takes into account the existence of a vulnerable group as well as the variability of the social relations of individuals. We develop a compartmentalized power-law model, with power-law connections…

物理与社会 · 物理学 2020-10-13 Simone Santini

Motivated by the increasing number of COVID-19 cases that have been observed in many countries after the vaccination and relaxation of non-pharmaceutical interventions, we propose a mathematical model on time-varying networks for the spread…

动力系统 · 数学 2022-03-09 Kathinka Frieswijk , Lorenzo Zino , Ming Cao

The optimal allocation of vaccines to population subgroups over time is a challenging health care management problem. In the context of a pandemic, the interaction between vaccination policies adopted by multiple agents and the cooperation…

最优化与控制 · 数学 2021-09-22 David Rey , Ahmed W Hammad , Meead Saberi

Optimizing the impact on the economy of control strategies aiming at containing the spread of COVID-19 is a critical challenge. We use daily new case counts of COVID-19 patients reported by local health administrations from different…

种群与进化 · 定量生物学 2021-03-12 Afroza Shirin , Yen Ting Lin , Francesco Sorrentino
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