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Parkinson's disease (PD) is a prevalent neurodegenerative disorder known for its impact on motor neurons, causing symptoms like tremors, stiffness, and gait difficulties. This study explores the potential of vocal feature alterations in PD…

Despite the promising performance of state of the art approaches for Parkinsons Disease (PD) detection, these approaches often analyze individual speech segments in isolation, which can lead to suboptimal results. Dysarthric cues that…

机器学习 · 计算机科学 2024-09-17 Shakeel A. Sheikh , Yacouba Kaloga , Md Sahidullah , Ina Kodrasi

Recent work in deep learning focuses on solving physical systems in the Ordinary Differential Equation or Partial Differential Equation. This current work proposed a variant of Convolutional Neural Networks (CNNs) that can learn the hidden…

机器学习 · 计算机科学 2021-11-02 Mansura Habiba , Barak A. Pearlmutter

The rapid advancement of medical technology has led to an exponential increase in multi-modal medical data, including imaging, genomics, and electronic health records (EHRs). Graph neural networks (GNNs) have been widely used to represent…

定量方法 · 定量生物学 2024-10-03 Favour Nerrise , Alice Louise Heiman , Ehsan Adeli

We designed a new artificial neural network by modifying the neural ordinary differential equation (NODE) framework to successfully predict the time evolution of the 2D mode profile in both the linear growth and nonlinear saturated stages.…

等离子体物理 · 物理学 2024-11-11 Bowen Zhu , Hao Wang , Jian Wu , Haijun Ren

In this work we propose a new biophysical computational model of brain regions relevant to Parkinson's Disease based on local field potential data collected from the brain of marmoset monkeys. Parkinson's disease is a neurodegenerative…

We propose characteristics-informed neural networks (CINN), a simple and efficient machine learning approach for solving forward and inverse problems involving hyperbolic PDEs. Like physics-informed neural networks (PINN), CINN is a…

机器学习 · 计算机科学 2023-01-16 Ulisses Braga-Neto

Mild cognitive impairment (MCI) is often at high risk of progression to Alzheimer's disease (AD). Existing works to identify the progressive MCI (pMCI) typically require MCI subtype labels, pMCI vs. stable MCI (sMCI), determined by whether…

图像与视频处理 · 电气工程与系统科学 2024-01-24 Chenhui Wang , Yiming Lei , Tao Chen , Junping Zhang , Yuxin Li , Hongming Shan

One of the most catastrophic neurological disorders worldwide is Parkinson's Disease. Along with it, the treatment is complicated and abundantly expensive. The only effective action to control the progression is diagnosing it in the early…

机器学习 · 计算机科学 2023-10-23 Md. Taufiqul Haque Khan Tusar , Md. Touhidul Islam , Abul Hasnat Sakil

Predicting the impact of treatments from observational data only still represents a majorchallenge despite recent significant advances in time series modeling. Treatment assignments are usually correlated with the predictors of the…

机器学习 · 计算机科学 2022-02-25 Edward De Brouwer , Javier González Hernández , Stephanie Hyland

The long-term progression of neurodegenerative diseases is commonly conceptualized as a spatiotemporal diffusion process that consists of a graph diffusion process across the structural brain connectome and a localized reaction process…

Operational weather prediction has long relied on physics-based numerical weather prediction (NWP), whose accuracy comes at the cost of substantial compute and complex simulation workflows. Recent transformer-based forecasters offer…

机器学习 · 计算机科学 2026-05-01 Hira Saleem , Flora Salim , Cormac Purcell

The uncertainty of clinical examinations frequently leads to irregular observation intervals in longitudinal imaging data, posing challenges for modeling disease progression.Most existing imaging-based disease prediction models operate in…

计算机视觉与模式识别 · 计算机科学 2025-11-26 Xin Hong , Ying Shi , Yinhao Li , Yen-Wei Chen

Physics-Informed Neural Networks (PINNs) and Neural Ordinary Differential Equations (NODEs) represent two distinct machine learning frameworks for modeling nonlinear neuronal dynamics. This study systematically evaluates their performance…

动力系统 · 数学 2026-03-31 Nikolaos M. Matzakos , Chrisovalantis Sfyrakis

Longitudinal analysis in medical imaging is crucial to investigate the progressive changes in anatomical structures or disease progression over time. In recent years, a novel class of algorithms has emerged with the goal of learning disease…

Parkinson's disease (PD) is the second most common neurodegenerative disease worldwide and affects around 1% of the (60+ years old) elderly population in industrial nations. More than 80% of PD patients suffer from motor symptoms, which…

Partial differential equations (PDEs) play a crucial role in studying a vast number of problems in science and engineering. Numerically solving nonlinear and/or high-dimensional PDEs is often a challenging task. Inspired by the traditional…

数值分析 · 数学 2022-01-11 Yihao Hu , Tong Zhao , Shixin Xu , Zhiliang Xu , Lizhen Lin

Neural ordinary differential equations (NODEs) have been proven useful for learning non-linear dynamics of arbitrary trajectories. However, current NODE methods capture variations across trajectories only via the initial state value or by…

机器学习 · 计算机科学 2023-11-14 Ilze Amanda Auzina , Çağatay Yıldız , Sara Magliacane , Matthias Bethge , Efstratios Gavves

Psychometric assessment instruments aid clinicians by providing methods of assessing the future risk of adverse events such as aggression. Existing machine learning approaches have treated this as a classification problem, predicting the…

机器学习 · 计算机科学 2023-12-05 Aidan Quinn , Melanie Simmons , Benjamin Spivak , Christoph Bergmeir

Increasing the layer number of on-chip photonic neural networks (PNNs) is essential to improve its model performance. However, the successively cascading of network hidden layers results in larger integrated photonic chip areas. To address…

机器学习 · 计算机科学 2023-02-08 Yun Zhao , Hang Chen , Min Lin , Haiou Zhang , Tao Yan , Xing Lin , Ruqi Huang , Qionghai Dai