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Knee osteoporosis weakens the bone tissue in the knee joint, increasing fracture risk. Early detection through X-ray images enables timely intervention and improved patient outcomes. While some researchers have focused on diagnosing knee…

图像与视频处理 · 电气工程与系统科学 2024-12-13 Ayesha Siddiqua , Rakibul Hasan , Anichur Rahman , Abu Saleh Musa Miah

Accurate blood glucose prediction can enable novel interventions for type 1 diabetes treatment, including personalized insulin and dietary adjustments. Although recent advances in transformer-based architectures have demonstrated the power…

定量方法 · 定量生物学 2025-05-15 Meryem Altin Karagoz , Marc D. Breton , Anas El Fathi

As populations age, the rise of multimorbidity poses a significant healthcare challenge. However, our ability to quantitatively forecast the progression of multimorbidity remains limited. Leveraging a nationwide dataset comprising…

物理与社会 · 物理学 2025-07-29 Katharina Ledebur , Alexandra Kautzky-Willer , Stefan Thurner , Peter Klimek

Predicting health risks from electronic health records (EHR) is a topic of recent interest. Deep learning models have achieved success by modeling temporal and feature interaction. However, these methods learn insufficient representations…

机器学习 · 计算机科学 2023-12-19 Zhihao Yu , Chaohe Zhang , Yasha Wang , Wen Tang , Jiangtao Wang , Liantao Ma

We develop a Causal-Deep Neural Network (CDNN) model trained in two stages to infer causal impact estimates at an individual unit level. Using only the pre-treatment features in stage 1 in the absence of any treatment information, we learn…

机器学习 · 计算机科学 2022-01-24 Naveen Nair , Karthik S. Gurumoorthy , Dinesh Mandalapu

A survival analysis model for predicting time-to-total knee replacement (TKR) was developed using features from medical images and clinical measurements. Supervised and self-supervised deep learning approaches were utilized to extract…

图像与视频处理 · 电气工程与系统科学 2024-11-19 Ozkan Cigdem , Shengjia Chen , Chaojie Zhang , Kyunghyun Cho , Richard Kijowski , Cem M. Deniz

Early detection of preventable diseases is important for better disease management, improved inter-ventions, and more efficient health-care resource allocation. Various machine learning approacheshave been developed to utilize information…

机器学习 · 计算机科学 2018-08-16 Jingshu Liu , Zachariah Zhang , Narges Razavian

Chronic kidney disease (CKD) is a major global health issue, affecting over 10% of the population and causing significant mortality. While kidney biopsy remains the gold standard for CKD diagnosis and treatment, the lack of comprehensive…

Chronic diseases such as diabetes are quite prevalent in the world and are responsible for a significant number of deaths per year. In addition, treatments for such chronic diseases account for a high healthcare cost. However, research has…

机器学习 · 计算机科学 2021-09-07 Asish Satpathy , Satyajit Behari

Colonoscopy screening effectively identifies and removes polyps before they progress to colorectal cancer (CRC), but current follow-up guidelines rely primarily on histopathological features, overlooking other important CRC risk factors.…

计算机视觉与模式识别 · 计算机科学 2025-04-15 Shuai Jiang , Christina Robinson , Joseph Anderson , William Hisey , Lynn Butterly , Arief Suriawinata , Saeed Hassanpour

Integrating multimodal Electronic Health Records (EHR) data, such as numerical time series and free-text clinical reports, has great potential in predicting clinical outcomes. However, prior work has primarily focused on capturing temporal…

机器学习 · 计算机科学 2025-11-10 Fuying Wang , Feng Wu , Yihan Tang , Lequan Yu

Autosomal Dominant Polycystic Kidney Disease (ADPKD) characterized by progressive growth of renal cysts is the most prevalent and potentially lethal monogenic renal disease, affecting one in every 500-100 people. Total Kidney Volume (TKV)…

计算机视觉与模式识别 · 计算机科学 2018-09-10 Deepak Keshwani , Yoshiro Kitamura , Yuanzhong Li

Longitudinal data in electronic health records (EHRs) represent an individual`s clinical history through a sequence of codified concepts, including diagnoses, procedures, medications, and laboratory tests. Generative pre-trained…

Introduction: Kidney function is reported using estimates of glomerular filtration rate (eGFR). However, eGFR values are recorded without reference to the creatinine (SCr) assays used to derive them, and newer assays were introduced at…

定量方法 · 定量生物学 2014-09-05 Norman Poh , Andrew McGovern , Simon de Lusignan

The Early diagnosis and treatment of depression is essential for effective treatment. Depression, while being one of the most common mental illnesses, is still poorly understood in both research and clinical practice. Among different…

信号处理 · 电气工程与系统科学 2023-03-13 Abdolkarim Saeedi , Arash Maghsoudi , Fereidoun Nowshiravan Rahatabad

Health registers contain rich information about individuals' health histories. Here our interest lies in understanding how individuals' health trajectories evolve in a nationwide longitudinal dataset with coded features, such as clinical…

机器学习 · 计算机科学 2024-12-13 Hans Moen , Vishnu Raj , Andrius Vabalas , Markus Perola , Samuel Kaski , Andrea Ganna , Pekka Marttinen

Background:Chronic kidney disease is one of the most prevalent non-communicable health issues globally, and high body mass index plays a significant role in the onset and progression of chronic kidney disease. Methods: Data on the disease…

种群与进化 · 定量生物学 2025-08-01 Yu Chen , Guangxi Wu

With the spread of COVID-19 over the world, the need arose for fast and precise automatic triage mechanisms to decelerate the spread of the disease by reducing human efforts e.g. for image-based diagnosis. Although the literature has shown…

The cause-specific cumulative incidence function (CIF) quantifies the subject-specific disease risk with competing risk outcome. With longitudinally collected biomarker data, it is of interest to dynamically update the predicted CIF by…

定量方法 · 定量生物学 2019-06-14 Cai Wu , Liang Li , Ruosha Li

In a worldwide health crisis as exigent as COVID-19, there has become a pressing need for rapid, reliable diagnostics. Currently, popular testing methods such as reverse transcription polymerase chain reaction (RT-PCR) can have high false…

图像与视频处理 · 电气工程与系统科学 2022-07-15 Justin Liu