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Transcranial electric stimulation (TES) can modulate intrinsic neural activity in the brain by injecting weak currents through electrodes attached to the scalp. TES has been widely used as a neuroscience tool to investigate how behavioural…

Objective. Personalized transcranial electrical stimulation (tES) has gained growing attention due to the substantial inter-individual variability in brain anatomy and physiology. While previous reviews have discussed the physiological…

神经元与认知 · 定量生物学 2025-11-06 Mo Wang , Kexin Zheng , Yingyue Xin , Xiang Chen , Yiling Liu , Huichun Luo , Jingsheng Tang , Tifei Yuan , Hongkai Wen , Pengfei Wei , Quanying Liu

Background and Objective: Transcranial temporal interference stimulation (tTIS) is a promising non-invasive brain stimulation technique in which interference between electrical current fields extends the possibilities of electrical brain…

数值分析 · 数学 2026-02-05 Santtu Söderholm , Maryam Samavaki , Sampsa Pursiainen

Purpose: This study investigates the feasibility of transcutaneous interferential spinal cord stimulation (tISCS), a novel non-invasive neuromodulation method, using temporal interference to enhance focality and comfort in spinal cord…

For decades, focal non-invasive neuromodulation of deep brain regions has not been possible because of the steep depth-focality trade-off of conventional non-invasive brain stimulation (NIBS) techniques, such as transcranial magnetic…

神经元与认知 · 定量生物学 2025-12-17 Pierre Vassiliadis , Elena Beanato , Maximilian J. Wessel , Friedhelm C. Hummel

Electro-stimulation or modulation of deep brain regions is commonly used in clinical procedures for the treatment of several nervous system disorders. In particular, transcranial direct current stimulation (tDCS) is widely used as an…

图像与视频处理 · 电气工程与系统科学 2020-04-29 Essam A. Rashed , Jose Gomez-Tames , Akimasa Hirata

Transcranial magnetic stimulation (TMS) is a popular method for the noninvasive stimulation of neurons in the brain. It has become a standard instrument in experimental brain research and is approved for a range of diagnostic and…

医学物理 · 物理学 2023-12-27 Max Koehler , Stefan Goetz

High-definition transcranial direct current stimulation (HD-tDCS) dosing in children remains largely empirical, relying on one-size-fits-all protocols despite rapid developmental changes in head anatomy and tissue properties that strongly…

定量方法 · 定量生物学 2025-12-02 Zeming Liu , Mo Wang , Xuanye Pan , Yuan Yang , Wilson Truccolo , Quanying Liu

This numerical simulation study investigates solving the L1-norm fitted and regularized (L1-L1) linear programming (LP) problem to find a well-localized volumetric current density in transcranial electrical stimulation (tES), where a…

最优化与控制 · 数学 2022-09-26 F. Galaz Prieto , M. Samavaki , S. Pursiainen

Transcranial Electrical Stimulation (tES) is a neuromodulation technique that utilizes electrodes on the scalp to stimulate target brain regions. tES has shown promise in treating many neurological conditions, such as stroke rehabilitation…

系统与控制 · 电气工程与系统科学 2025-02-04 Chaitanya Goswami , Pulkit Grover

Transcranial direct current stimulation is a non-invasive brain stimulation technique which modifies neural excitability by providing weak currents through scalp electrodes. The aim of this study is to introduce and analyze a novel…

最优化与控制 · 数学 2016-09-27 Sven Wagner , Martin Burger , Carsten H. Wolters

Transcranial magnetic stimulation (TMS) is a technique for noninvasively stimulating a brain area for therapeutic, rehabilitation treatments and neuroscience research. Despite our understanding of the physical principles and experimental…

神经元与认知 · 定量生物学 2020-12-30 Jose Gomez-Tames , Ilkka Laakso , Akimasa Hirata

Electromagnetic stimulation of the human brain is a key tool for the neurophysiological characterization and diagnosis of several neurological disorders. Transcranial magnetic stimulation (TMS) is one procedure that is commonly used…

机器学习 · 计算机科学 2020-02-04 Essam A. Rashed , Jose Gomez-Tames , Akimasa Hirata

Background: Spinal cord injury (SCI) rehabilitation remains a major clinical challenge, with limited treatment options for functional recovery. Temporal interference (TI) electrical stimulation has emerged as a promising non-invasive…

医学物理 · 物理学 2025-03-07 Xu Xie , Yuchen Xu , Huilin Mou , Xi Li , Li Zhang , Zehao Sheng , Weidong Chen , Shaomin Zhang , Ruidong Cheng , Minmin Wang

In several diagnosis and therapy procedures based on electrostimulation effect, the internal physical quantity related to the stimulation is the induced electric field. To estimate the induced electric field in an individual human model,…

医学物理 · 物理学 2021-02-03 Essam A. Rashed , Jose Gomez-Tames , Akimasa Hirata

Spinal cord injury (SCI) is a debilitating condition that often results in significant motor and sensory deficits, impacting the quality of life. Current rehabilitation methods, including physical therapy and electrical stimulation, offer…

神经元与认知 · 定量生物学 2024-12-18 Ruidong Cheng , Yuling Shao , Xi Li , Li Zhang , Zehao Sheng , Chenyang Li , Xu Xie , Huilin Mou , Weidong Chen , Shaomin Zhang , Yuchen Xu , Minmin Wang

At the group-level, deep brain stimulation leads to significant therapeutic benefit in a multitude of neurological and neuropsychiatric disorders. At the single-patient level, however, symptoms may sometimes persist despite "optimal"…

A major shortcoming of medical practice is the lack of an objective measure of conscious level. Impairment of consciousness is common, e.g. following brain injury and seizures, which can also interfere with sensory processing and volitional…

神经元与认知 · 定量生物学 2025-12-24 Alexis Pomares Pastor , Ines Ribeiro Violante , Gregory Scott

Transcranial focused ultrasound (tFUS) offers noninvasive access to deep brain circuits but remains limited by skull-induced phase aberration, acoustic impedance mismatch, and poor volumetric control of intracranial pressure fields.…

Background: Transcranial magnetic stimulation (TMS) is a powerful tool to investigate neurophysiology of the human brain and treat brain disorders. Traditionally, therapeutic TMS has been applied in a one-size-fits-all approach,…

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